期刊
LAB ON A CHIP
卷 10, 期 13, 页码 1678-1682出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c000163e
关键词
-
类别
资金
- National Institutes of Health (NIH) [PN2EY018228]
- NASA National Space Biomedical Research Institute (NSBRI) [NCC 9-58-317]
- NATIONAL EYE INSTITUTE [PN2EY018228] Funding Source: NIH RePORTER
This paper presents a microfluidic device for sorting embryoid bodies (EBs) with large dynamic size ranges up to 300 mu m. The proposed separation scheme utilizes appropriately spaced pillars within a microchannel to alter the fluid flow pathway, thus allowing particles of defined sizes to be diverted towards specific flow paths. We test the device functionality by separating polystyrene beads 90, 175 and 275 mu m in diameter, demonstrating separation efficiencies approaching 100%. We then demonstrate for the first time on-chip separation of mouse EBs, which were separated into three size groups. The ability to extract specific size ranges of EBs will greatly facilitate their subsequent differentiation studies.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据