Paeoniflorin exerts analgesic and hypnotic effects via adenosine A1 receptors in a mouse neuropathic pain model

Gelsemine alleviates both neuropathic pain and sleep disturbance in partial sciatic nerve ligation mice

(2015) Yu-er Wu et al.   ACTA PHARMACOLOGICA SINICA

Antinociceptive and hypnotic activities of pregabalin in a neuropathic pain-like model in mice

(2015) Tian-Xiao Wang et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Antineuropathic effect of 7-hydroxy-3,4-dihydrocadalin in streptozotocin-induced diabetic rodents

(2014) Héctor Isaac Rocha-González et al.   BMC Complementary and Alternative Medicine

Norisoboldine attenuates inflammatory pain via the adenosine A1 receptor

(2014) X. Gao et al.   EUROPEAN JOURNAL OF PAIN

TRR469, a potent A1 adenosine receptor allosteric modulator, exhibits anti-nociceptive properties in acute and neuropathic pain models in mice

(2014) Fabrizio Vincenzi et al.   NEUROPHARMACOLOGY

Piromelatine exerts antinociceptive effect via melatonin, opioid, and 5HT1A receptors and hypnotic effect via melatonin receptors in a mouse model of neuropathic pain

(2014) Yuan-Yuan Liu et al.   PSYCHOPHARMACOLOGY

Implications and mechanism of action of gabapentin in neuropathic pain

(2013) Ankesh Kukkar et al.   ARCHIVES OF PHARMACAL RESEARCH

GABA transporter-1 inhibitor NO-711 alters the EEG power spectra and enhances non-rapid eye movement sleep during the active phase in mice

(2013) Xin-Hong Xu et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Morphine Inhibits Sleep-Promoting Neurons in the Ventrolateral Preoptic Area Via Mu Receptors and Induces Wakefulness in Rats

(2013) Qin Wang et al.   NEUROPSYCHOPHARMACOLOGY

Honokiol promotes non-rapid eye movement sleep via the benzodiazepine site of the GABAAreceptor in mice

(2012) Wei-Min Qu et al.   BRITISH JOURNAL OF PHARMACOLOGY

Recombinant Ecto-5′-Nucleotidase (CD73) Has Long Lasting Antinociceptive Effects That are Dependent on Adenosine A1 Receptor Activation

(2012) Nathaniel A Sowa et al.   Molecular Pain

Magnolol, a major bioactive constituent of the bark of Magnolia officinalis, induces sleep via the benzodiazepine site of GABAA receptor in mice

(2012) Chang-Rui Chen et al.   NEUROPHARMACOLOGY

Evidence for a differential opioidergic involvement in the analgesic effect of antidepressants: prediction for efficacy in animal models of neuropathic pain?

(2011) A-S Wattiez et al.   BRITISH JOURNAL OF PHARMACOLOGY

Paeoniflorin suppresses the expression of intercellular adhesion molecule-1 (ICAM-1) in endotoxin-treated human monocytic cells

(2011) Lei Jin et al.   BRITISH JOURNAL OF PHARMACOLOGY

Impact of Pregabalin Treatment on Pain, Pain-Related Sleep Interference and General Well-Being in Patients with Neuropathic Pain

(2011) Emmanouil Anastassiou et al.   CLINICAL DRUG INVESTIGATION

The Role of Adenosine in the Regulation of Sleep

(2011) Zhi-Li Huang et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Curcumin exerts antinociceptive effects in a mouse model of neuropathic pain: Descending monoamine system and opioid receptors are differentially involved

(2011) Xin Zhao et al.   NEUROPHARMACOLOGY

Sleep disturbances in a neuropathic pain-like condition in the mouse are associated with altered GABAergic transmission in the cingulate cortex

(2011) Minoru Narita et al.   PAIN

International Union of Basic and Clinical Pharmacology. LXXXI. Nomenclature and Classification of Adenosine Receptors--An Update

(2011) B. B. Fredholm et al.   PHARMACOLOGICAL REVIEWS

Differential effects of adenosine A1 receptor on pain-related behavior in normal and nerve-injured rats

(2010) Qing-Juan Gong et al.   BRAIN RESEARCH

Negative Mood Mediates the Effect of Poor Sleep on Pain Among Chronic Pain Patients

(2010) Erin M. OʼBrien et al.   CLINICAL JOURNAL OF PAIN

Antinociceptive and anti-inflammatory properties of 7-hydroxycoumarin in experimental animal models: potential therapeutic for the control of inflammatory chronic pain

(2010) Taís A. De Almeida Barros et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Neuropathic pain: diagnosis, pathophysiological mechanisms, and treatment

(2010) Ralf Baron et al.   LANCET NEUROLOGY

Adenosine A1 receptors mediate local anti-nociceptive effects of acupuncture

(2010) Nanna Goldman et al.   NATURE NEUROSCIENCE

Direct blockade of inflammatory hypernociception by peripheral A1 adenosine receptors: Involvement of the NO/cGMP/PKG/KATP signaling pathway

(2010) Flávia Oliveira Lima et al.   PAIN

Alleviating Neuropathic Pain Hypersensitivity by Inhibiting PKM  in the Anterior Cingulate Cortex

(2010) X.-Y. Li et al.   SCIENCE

Role of adenosine A1 receptor in the perifornical–lateral hypothalamic area in sleep–wake regulation in rats

(2009) Md. Noor Alam et al.   BRAIN RESEARCH

Neuronal hyperactivity at the spinal cord and periaqueductal grey during painful diabetic neuropathy: Effects of gabapentin

(2009) Carla Morgado et al.   EUROPEAN JOURNAL OF PAIN

Analgesic effect of paeoniflorin in rats with neonatal maternal separation-induced visceral hyperalgesia is mediated through adenosine A1 receptor by inhibiting the extracellular signal-regulated protein kinase (ERK) pathway

(2009) Xiao-Jun Zhang et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Antiallergic effect of the root of Paeonia lactiflora and its constituents paeoniflorin and paeonol

(2008) Bomi Lee et al.   ARCHIVES OF PHARMACAL RESEARCH

Measurement of Immediate-Early Gene Activation-c-fosand Beyond

(2008) K. J. Kovács   JOURNAL OF NEUROENDOCRINOLOGY

 -Opioid Receptor-Mediated Depression of the Hypothalamic Hypocretin/Orexin Arousal System

(2008) Y. Li et al.   JOURNAL OF NEUROSCIENCE

The Analgesic Effect of Paeoniflorin on Neonatal Maternal Separation–Induced Visceral Hyperalgesia in Rats

(2008) Xiao-jun Zhang et al.   JOURNAL OF PAIN

Repeated cannabinoid injections into the rat periaqueductal gray enhance subsequent morphine antinociception

(2008) Adrianne R. Wilson et al.   NEUROPHARMACOLOGY

Adenosine in the tuberomammillary nucleus inhibits the histaminergic system via A1 receptors and promotes non-rapid eye movement sleep

(2008) Y. Oishi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cortical excitation and chronic pain

(2008) Min Zhuo   TRENDS IN NEUROSCIENCES