Article
Psychology, Developmental
Sandra Thijssen, Paul F. Collins, Hannah Weiss, Monica Luciana
Summary: Higher externalizing behavior is associated with increased resting-state attunement between the amygdala and ACC/OFC across adolescence and young adulthood. The association with amygdala-ACC connectivity is primarily driven by externalizing behavior at baseline, while the main effect on amygdala-OFC functional connectivity is driven by changes in externalizing behavior relative to baseline. No evidence was found for differential developmental trajectories of frontoamygdalar connectivity for different levels of externalizing behavior.
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY
(2021)
Article
Immunology
Johnna R. Swartz, Angelica F. Carranza, Laura M. Tully, Annchen R. Knodt, Janina Jiang, Michael R. Irwin, Camelia E. Hostinar
Summary: The study found associations between peripheral inflammation and adolescent brain connectivity, with higher TNF-α levels linked to changes in neural network connections. Associations with IL-6 and CRP were not significant, suggesting that inflammation may have unique effects on brain connectivity during adolescence.
BRAIN BEHAVIOR AND IMMUNITY
(2021)
Article
Psychology, Developmental
Z. A. Kovacs-Balint, J. Raper, R. Richardson, A. Gopakumar, K. P. Kettimuthu, M. Higgins, E. Feczko, E. Earl, K. F. Ethun, L. Li, M. Styner, D. Fair, J. Bachevalier, M. M. Sanchez
Summary: This study investigated the impact of male pubertal maturation on physical growth and the development of neural circuits regulating stress, emotional, and cognitive control using nonhuman primates as a model. By collecting longitudinal data, including physical and pubertal measures, as well as brain structural and functional MRI scans, the researchers found developmental changes in several brain regions and functional connectivity. Testicular size was a better predictor of brain structural maturation, while testosterone levels were strongly associated with functional connectivity development. Further research is expected to reveal more significant pubertal-dependent maturation in these neural circuits during and after male puberty.
DEVELOPMENTAL COGNITIVE NEUROSCIENCE
(2023)
Article
Multidisciplinary Sciences
Byung-Hoon Kim, Min-Kyeong Kim, Hye-Jeong Jo, Jae-Jin Kim
Summary: Social anxiety is prevalent among young adults, and machine learning models using brain functional radiomic features can successfully predict its level.
SCIENTIFIC REPORTS
(2022)
Article
Behavioral Sciences
Leehyun Yoon, Angelica F. Carranza, Johnna R. Swartz
Summary: This study examines the association between personality dimensions and brain functional connectivity in adolescents, specifically focusing on extraversion and agreeableness. The results reveal sex-specific neural connectivity patterns associated with these personality dimensions and suggest that intrinsic functional connectivity contributes to individual differences in extraversion and agreeableness in adolescents.
FRONTIERS IN BEHAVIORAL NEUROSCIENCE
(2022)
Article
Biochemistry & Molecular Biology
Laura Sanchez-Marin, Maria Flores-Lopez, Ana L. Gavito, Juan Suarez, Francisco Javier Pavon-Moron, Fernando Rodriguez de Fonseca, Antonia Serrano
Summary: Repeated stress and alcohol exposure during adolescence can lead to long-term anxiety-like behavior in male rats, but with different mechanisms involved in the brain.
Article
Multidisciplinary Sciences
Ondrej Zika, Katja Wiech, Andrea Reinecke, Michael Browning, Nicolas W. Schuck
Summary: This study investigates the influence of trait anxiety on hidden-state inference. The results show that trait anxiety is associated with rapid expectation switches after contingency reversals and reduced oddball learning. Furthermore, trait anxiety is related to better fit of a state inference model when contingency changes are large. These findings support the role of hidden-state inference in anxiety-related fear relapse phenomena.
NATURE COMMUNICATIONS
(2023)
Article
Neurosciences
Merridee J. Lefner, Alexa P. Magnon, James M. Gutierrez, Matthew R. Lopez, Matthew J. Wanat
Summary: This study investigates the impact of temporal delays on reward preference by examining rats' preference for different flavored rewards during a free-feeding test, finding that temporal delays enhance preference for initially less desirable rewards.
JOURNAL OF NEUROSCIENCE
(2021)
Article
Clinical Neurology
Xuejun Jiang, Feng Wu, Yifan Zhang, Huizi Li, Jiahui Kang, Lingtao Kong, Fei Wang, Yanqing Tang
Summary: This study investigated the association between brain function and gender in bipolar disorder using amplitude of low-frequency fluctuations (ALFF). The results indicated gender differences in dysfunction of the cortico-limbic neural system in BD. Male and female patients with BD showed different patterns of ALFF in various brain regions.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Multidisciplinary Sciences
Atsushi Fujimoto, Elisabeth A. Murray, Peter H. Rudebeck
Summary: Decision-making and representations of arousal are closely related, with an optimal level of bodily arousal facilitating performance. The interactions between these processes at the level of single neurons and neural circuits remain unclear.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Neurosciences
Edmund T. Rolls, Gustavo Deco, Chu-Chung Huang, Jianfeng Feng
Summary: The amygdala and orbitofrontal cortex are involved in emotion. Through experiments on 171 humans from the Human Connectome Project, it was found that the human amygdala has fewer effective connections with cortical regions compared to the orbitofrontal cortex. It is proposed that the amygdala is primarily involved in autonomic and conditioned responses, rather than declarative emotion.
PROGRESS IN NEUROBIOLOGY
(2023)
Article
Psychiatry
Haixia Zheng, Bart N. Ford, Rayus Kuplicki, Kaiping Burrows, Peter W. Hunt, Jerzy Bodurka, T. Kent Teague, Michael R. Irwin, Robert H. Yolken, Martin P. Paulus, Jonathan Savitz
Summary: This study found that individuals with positive HCMV serostatus had reduced gray matter volume in multiple brain regions compared to individuals with negative HCMV serostatus, and also showed differences in resting-state functional connectivity.
TRANSLATIONAL PSYCHIATRY
(2021)
Article
Neurosciences
Maia S. Pujara, Nicole K. Ciesinski, Joseph F. Reyelts, Sarah E. V. Rhodes, Elisabeth A. Murray
Summary: This study found that the functional interaction between the amygdala and prefrontal cortex is crucial for supporting social and nonsocial valuation. Different regions of the prefrontal cortex exhibit distinct deficits when impaired.
JOURNAL OF NEUROSCIENCE
(2022)
Article
Psychology, Developmental
Theresa W. Cheng, Kathryn L. Mills, Oscar Miranda Dominguez, Dagmar Zeithamova, Anders Perrone, Darrick Sturgeon, Sarah W. Feldstein Ewing, Philip A. Fisher, Jennifer H. Pfeifer, Damien A. Fair, Kristen L. Mackiewicz Seghete
Summary: Characterizing typologies of childhood adversity and their neurobiological grounding may provide insights into how different histories of adversity influence adolescent behavior, cognition, and psychopathology through altered amygdala resting-state functional connectivity. Unique regions of altered connectivity were identified in both general and dimensional models, indicating potential pathways by which distinct adversities impact neural function in adolescents.
DEVELOPMENTAL COGNITIVE NEUROSCIENCE
(2021)
Article
Endocrinology & Metabolism
Esmeralda Hidalgo-Lopez, Isabel Noachtar, Belinda Pletzer
Summary: This study investigated the influence of anti-androgenic and progestin on the resting state functional connectivity (rs-FC) between the anterior cingulate cortex (ACC) and amygdala, while controlling for the androgenicity of progestin. The results showed that regardless of the androgenicity of progestin, rs-FC between the amygdala and frontal areas, as well as between ACC and temporoparietal areas, decreased with longer duration of HC use. However, the type of progestin had different effects on the gray matter volume of the left ACC and the connectivity between bilateral ACC and the right inferior frontal gyrus.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Neurosciences
Lara M. Wierenga, Martijn P. van den Heuvel, Bob Oranje, Jay N. Giedd, Sarah Durston, Jiska S. Peper, Timothy T. Brown, Eveline A. Crone
HUMAN BRAIN MAPPING
(2018)
Article
Neurosciences
N. E. Blankenstein, E. Schreuders, J. S. Peper, E. A. Crone, A. C. K. van Duijvenvoorde
Article
Behavioral Sciences
Jochem P. Spaans, Sabine Peters, Eveline A. Crone
COGNITIVE AFFECTIVE & BEHAVIORAL NEUROSCIENCE
(2019)
Article
Neurosciences
Anna C. K. van Duijvenvoorde, Bianca Westhoff, Frank de Vos, Lara M. Wierenga, Eveline A. Crone
HUMAN BRAIN MAPPING
(2019)
Article
Neurosciences
Eduard T. Klapwijk, Ferdi van de Kamp, Mara van der Meulen, Sabine Peters, Lara M. Wierenga
Article
Neurosciences
Renske van der Cruijsen, Renate Buisman, Kayla Green, Sabine Peters, Eveline Crone
SOCIAL COGNITIVE AND AFFECTIVE NEUROSCIENCE
(2019)
Article
Behavioral Sciences
Renske Van der Cruijsen, Sabine Peters, Kelly P. M. Zoetendaal, Jennifer H. Pfeifer, Eveline A. Crone
Article
Neurosciences
Lina van Drunen, Simone Dobbelaar, Renske van der Cruijsen, Mara van der Meulen, Michelle Achterberg, Lara M. Wierenga, Eveline A. Crone
Summary: This study investigated the genetic and environmental influences on the behavioral and neural correlates of self-concept in middle childhood using a twin sample. The results showed that academic self-evaluations were mainly influenced by genetic factors, while social self-evaluations were more affected by shared environmental factors.
HUMAN BRAIN MAPPING
(2021)
Review
Psychology, Multidisciplinary
Eveline A. Crone, Michelle Achterberg
Summary: Adolescence is a critical period for social adjustment, where adolescents begin to differentiate more between recipients and contexts in prosocial behavior. Social brain development during adolescence is influenced by environmental factors, highlighting the importance of this developmental stage. The COVID-19 pandemic has long-term effects on current generation of adolescents, but also presents opportunities for engaging in acts of kindness.
CURRENT OPINION IN PSYCHOLOGY
(2022)
Article
Neurosciences
Ilse H. van de Groep, Marieke G. N. Bos, Lucres M. C. Jansen, Arne Popma, Eveline A. Crone
Summary: Self-concept is influenced by social experiences, and the neural and behavioral development of self-concept in individuals with a history of antisocial behavior is not well understood. This study examined neural responses to self-evaluations in young adults with a history of antisocial behavior and found a negative association between current psychopathic traits and prosocial self-concept and medial prefrontal cortex activity during self-evaluation.
SOCIAL COGNITIVE AND AFFECTIVE NEUROSCIENCE
(2023)
Article
Education & Educational Research
L. P. E. van der Aar, E. A. Crone, S. Peters
MIND BRAIN AND EDUCATION
(2019)
Article
Neurosciences
L. P. E. van der Aar, S. Peters, R. van der Cruijsen, E. A. Crone
TRENDS IN NEUROSCIENCE AND EDUCATION
(2019)
Article
Psychology, Developmental
L. P. E. van der Aar, S. Peters, E. A. Crone
COGNITIVE DEVELOPMENT
(2018)
Article
Psychology, Educational
Elisabeth Schreuders, Barbara R. Braams, Neeltje E. Blankenstein, Jiska S. Peper, Berna Guroglu, Eveline A. Crone
Article
Psychology, Developmental
Geert-Jan Will, Eveline A. Crone, Pol A. C. van Lier, Berna Guroglu
DEVELOPMENTAL SCIENCE
(2018)
Article
Endocrinology & Metabolism
Shanshan Xiao, Natalie C. Ebner, Amirhossein Manzouri, Tie-Qiang Li, Diana S. Cortes, Kristoffer N. T. Mansson, Hakan Fischer
Summary: The mechanisms through which intranasal oxytocin affects the brain are not fully understood, but recent research suggests that brain regions with a higher density of oxytocin receptors may play a key role. This study used resting-state fMRI to investigate the effects of intranasal oxytocin administration on connectivity between these receptor-enriched regions and other regions in the brain, and found that the effects varied depending on the age of the participants.
PSYCHONEUROENDOCRINOLOGY
(2024)
Article
Endocrinology & Metabolism
Lisa Haase, Antonia Vehlen, Julia Strojny, Gregor Domes
Summary: This study found no significant changes in the cortisol awakening response (CAR) over the menstrual cycle, and no significant association with variations in estradiol and progesterone. These results suggest that CAR is largely robust against hormonal variations across the menstrual cycle.
PSYCHONEUROENDOCRINOLOGY
(2024)
Article
Endocrinology & Metabolism
Derek Schaeuble, Tyler Wallace, Sebastian A. Pace, Shane T. Hentges, Brent Myers
Summary: Depression and cardiovascular disease are influenced by daily life stress, but the biological mechanisms behind this connection are not well understood. This study shows that the ventromedial prefrontal cortex (vmPFC) plays a role in regulating stress responses and behavior, with sex-specific effects. In males, the vmPFC-PH circuitry promotes positive motivation and reduces stress responses, while in females it elevates stress responses. This suggests that cortical regulation of stress reactivity and behavior is mediated by projections to the hypothalamus in a sex-specific manner.
PSYCHONEUROENDOCRINOLOGY
(2024)
Article
Endocrinology & Metabolism
Jose M. Guzman, Montana H. Boone, Gabriela L. Suarez, Colter Mitchell, Christopher S. Monk, Luke W. Hyde, Nestor L. Lopez-Duran
Summary: The COVID-19 pandemic has led to increased life stress and internalizing disorders, with a disproportionate impact on women. This study focused on the neuroendocrinology of stress-related disorders and found that women have lower cortisol responses and higher DHEA responses to stress. However, lower cortisol and higher DHEA are associated with internalizing disorders in women, while the opposite is true in men. The study also examined the relationship between COVID-related stress and internalizing symptoms and found gender differences in the association between DHEA and cortisol and internalizing outcomes. These findings suggest distinct neuroendocrine pathways for stress-related disorders in young men and women.
PSYCHONEUROENDOCRINOLOGY
(2024)
Article
Endocrinology & Metabolism
Meriah L. Dejoseph, Keira B. Leneman, Alyssa R. Palmer, Emily R. Padrutt, Otiti A. Mayo, Daniel Berry
Summary: Childhood and adolescence are critical periods for the development of the stress response system. This study found a modest positive relation between the adrenocortical and sympathetic systems, as well as between the adrenocortical and parasympathetic systems. The strength of these associations varied based on methodological and sociodemographic characteristics.
PSYCHONEUROENDOCRINOLOGY
(2024)
Article
Endocrinology & Metabolism
Qiong Xiang, Jia-Sheng Tao, Shuai Dong, Xiao-Lin Liu, Liang Yang, Li-Ni Liu, Jing Deng, Xian-Hui Li
Summary: Chronic hyperglycemia accelerates the pathological process of cognitive dysfunction, but the heterogeneity of hippocampal cells under long-term high glucose conditions is not well known. In this study, single-cell RNA sequencing was performed on diabetic mice, and distinct cell sub-clusters and important genes involved in neuroplasticity regulation were identified.
PSYCHONEUROENDOCRINOLOGY
(2024)
Article
Endocrinology & Metabolism
Roger Mcintosh, Hannah Hoogerwoerd, Salman S. Ahmad, Cassandra Michel, Kaitlyn Dillon, Mahendra Kumar, Gail Ironson
Summary: The study found that a 4-session guided written emotional disclosure intervention led to significant reductions in total output and concentration of epinephrine in urine for up to 6 months in individuals living with HIV. This effect was especially pronounced in women. However, there were no significant changes in norepinephrine output in urine.
PSYCHONEUROENDOCRINOLOGY
(2024)
Article
Endocrinology & Metabolism
Meredith Gruhn, Adam Bryant Miller, Tory A. Eisenlohr-Moul, Sophia Martin, Matthew G. Clayton, Matteo Giletta, Paul D. Hastings, Matthew K. Nock, Karen D. Rudolph, George M. Slavich, Mitchell J. Prinstein, Margaret A. Sheridan
Summary: This study investigates how early life adversity characterized by threat impacts the association between neural activity and cortisol production during emotion processing. The results suggest that threat exposure may moderate the relationship between neural activation and cortisol response.
PSYCHONEUROENDOCRINOLOGY
(2024)
