期刊
KOREAN JOURNAL OF CHEMICAL ENGINEERING
卷 30, 期 1, 页码 1-10出版社
KOREAN INSTITUTE CHEMICAL ENGINEERS
DOI: 10.1007/s11814-012-0208-8
关键词
Hydrogenase; Hydrogen; Oxygen-tolerance; Maturation; Heterologous Expression
资金
- Manpower Development Program for Marine Energy
- Ministry of Land, Transport and Maritime Affairs, Korea
Despite increasing interest in hydrogen (H-2) as an alternative energy carrier, the current production of H-2 still depends on fossil fuels. Biotechnological hydrogen production can provide a more sustainable way to generate H-2. Hydrogenases are key enzymes involved in hydrogen metabolism of microorganisms with roles of H-2 oxidation or evolution. They have potential applications in H-2 production in vivo, in vitro and fuel cell. Important achievements have been made over the past decade in our understanding of hydrogenase and its biotechnological application as catalyst for H-2 production and fuel cell. This review summarizes recent progress in the study of hydrogenases, involving strategies for biosynthesis, maturation process, isolation of novel hydrogenases, heterologous expression system, structural feature of oxygen (O-2)-tolerant hydrogenases, and biotechnological applications for viable H-2 technology.
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