期刊
KIDNEY INTERNATIONAL
卷 85, 期 5, 页码 1009-1011出版社
ELSEVIER SCIENCE INC
DOI: 10.1038/ki.2013.440
关键词
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资金
- NIDDK NIH HHS [P30 DK096493, T32-DK007731, R01-DK094987, T32 DK007731, R01-DK087707, P30-DK096493] Funding Source: Medline
The role of the circulating renin-angiotensin system (RAS) in regulating Systemic blood pressure and sodium balance is well established. More recently, researchers have turned their focus to the local generation of angiotensin II (Ang II) in specific tissues. Matsusaka et al. revisit the renal RAS and provide evidence that liver-derived angiotensinogen (AGT) is a major determinant of renal Ang II levels in a model of podocyte injury.
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