Article
Medicine, General & Internal
Janine Hawkins, Nigel Smeeton, Amanda Busby, David Wellsted, Beth Rider, Julia Jones, Retha Steenkamp, Catherine Stannard, Rachel Gair, Sabine N. van der Veer, Claire Corps, Ken Farrington
Summary: The study found that patient experience of care in advanced kidney disease patients undergoing maintenance haemodialysis is primarily determined by the characteristics of the treatment centre rather than the patients themselves. Further research is needed to identify the specific centre characteristics that impact patient experience.
Article
Medicine, General & Internal
Janine Wirkner, Matthias Scheuch, Thomas Dabers, Sabrina Freiin von Rheinbaben, Beate Fiene, Simone Aymanns, Karlhans Endlich, Nicole Endlich, Uwe Lendeckel, Rainer Rettig, Hans Joergen Grabe, Sylvia Stracke
Summary: This study examined various factors influencing health-related quality of life (HRQOL) in chronic kidney disease (CKD) patients, with a focus on the impact of dialysis, depression, and diabetes. The results highlighted the importance of recognizing and treating depression to improve HRQOL and potentially enhance patient outcomes and reduce hospitalization rates.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Multidisciplinary Sciences
Yukio Maruyama, Masaaki Nakayama, Atsushi Ueda, Mariko Miyazaki, Takashi Yokoo
Summary: The study found that there was no significant association between different dialysis modalities (HD, online HDF, PD, and combined therapy with PD and HD) and the prevalence or severity of fatigue. Age, body mass index, creatinine, and employment status were associated with the presence or severity of fatigue.
Article
Health Care Sciences & Services
Ok-Hee Cho, Insook Hong, Hyekyung Kim
Summary: This study investigated the impact of illness uncertainty and fatigue on the health-related quality of life of dialysis patients. The results showed that patients on peritoneal dialysis experienced higher levels of fatigue. Factors such as fatigue, employment status, exercise, uncertainty, educational level, and smoking were found to influence the physical and mental health-related quality of life of patients. It is recommended that clinicians assess fatigue levels and implement multidisciplinary interventions to manage it, while considering education level, employment status, and providing tailored interventions to deal with disease uncertainty.
Article
Integrative & Complementary Medicine
Sevil Bicer, Sultan Tasci
Summary: This study investigated the effect of acupressure on the Neiguan (P6) acupuncture point during hemodialysis. It was found that acupressure on this point can regulate blood pressure and alleviate symptoms such as pain and fatigue.
ALTERNATIVE THERAPIES IN HEALTH AND MEDICINE
(2022)
Review
Psychiatry
Jiaying Li, Juan Yin, Ahmed Waqas, Zeyu Huang, Hongji Zhang, Manqing Chen, Yufei Guo, Atif Rahman, Lei Yang, Xiaomei Li
Summary: This study evaluated the health-related quality of life (HRQoL) of mothers with perinatal depression and compared them with non-depressed mothers. The findings showed that mothers with perinatal depression reported significantly poorer scores across all domains of quality of life compared to non-depressed mothers. There was no significant difference in HRQoL scores between mothers with antepartum and postpartum depression. Mothers with perinatal depression in higher-income countries reported higher disability in role-physical and social functioning domains compared to those from lower-income countries.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Urology & Nephrology
Julia M. T. Colombijn, Anna A. Bonenkamp, Anita van Eck van der Sluijs, Joost A. Bijlsma, Arnold H. Boonstra, Akin Ozyilmaz, Alferso C. Abrahams, Brigit C. van Jaarsveld
Summary: A higher number of medications were associated with a lower HRQoL, more symptoms, and worse self-rated health in dialysis patients after adjusting for confounders such as comorbidity.
AMERICAN JOURNAL OF NEPHROLOGY
(2021)
Article
Multidisciplinary Sciences
Suresh Ponnuvel, Gnanadurai John Fletcher, Raghavendran Anantharam, Santosh Varughese, Vinoy George David, Priya Abraham
Summary: HCVcAg demonstrates excellent specificity and sensitivity in identifying active HCV infection in hemodialysis and renal transplant patients, with good correlation to HCV RNA. This Indian study establishes HCVcAg as a reliable and cost-effective direct marker for managing HCV infection in these patient populations.
Article
Clinical Neurology
Meredith A. Bock, Ethan G. Brown, Li Zhang, Caroline Tanner
Summary: This study found significant correlations between depression, motor symptoms, medical comorbidities, and HRQOL in a large online cohort of Parkinson's disease patients. Neuropsychiatric symptoms and falls had the most negative impact on HRQOL. Motor symptoms may have differential effects on HRQOL in different demographic and clinical subpopulations.
Article
Dermatology
Iltefat H. Hamzavi, Kristen Bibeau, Pearl Grimes, John E. Harris, Nanja van Geel, Davinder Parsad, Mukta Tulpule, Jackie Gardner, Yan Valle, Gaone Tlhong Matewa, Christine LaFiura, Haobo Ren, Khaled Ezzedine
Summary: The VALIANT study is the first global survey to explore the natural history and management of vitiligo from the perspectives of patients and healthcare professionals. The findings reveal that patients and healthcare professionals have similar treatment goals and express frustration with the lack of effective therapies. The survey highlights the importance of earlier diagnosis and improved disease management for vitiligo.
BRITISH JOURNAL OF DERMATOLOGY
(2023)
Article
Urology & Nephrology
Kathryn Taylor, Nadia M. Chu, Xiaomeng Chen, Zhan Shi, Eileen Rosello, Sneha Kunwar, Paul Butz, Silas P. Norman, Deidra C. Crews, Keiko Greenberg, Aarti Mathur, Dorry L. Segev, Tariq Shafi, Mara A. McAdams-DeMarco
Summary: The study found that kidney transplant candidates reported a high symptom burden at evaluation, which was associated with waitlist mortality risk, but after kidney transplantation, symptoms improved, especially in the first 3 months.
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
(2021)
Article
Urology & Nephrology
Richard W. Corbett, Hannah Beckwith, Gaetano Lucisano, Edwina A. Brown
Summary: Peritoneal dialysis allows for home-based therapy and greater autonomy, leading to improved satisfaction compared to in-center care. However, the treatment burden remains significant, highlighting the importance of person-centered care. Shared decision making is central to prescribing PD and balancing the benefits and burdens of treatment.
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
(2023)
Article
Urology & Nephrology
Chunyan Yi, Hongjian Ye, Jianxiong Lin, Yao Chang, Xiaodan Zhang, Ting Zhou, Rui Yang, Xiao Yang
Summary: This study investigated the incidence of pain in peritoneal dialysis (PD) patients and analyzed the correlation between pain and quality of life. The results showed that the main cause of pain was calcium and phosphorus metabolism disorder. Older age and higher intact parathyroid hormone level were independent risk factors for pain. Pain was independently associated with depressive symptoms, sleep quality, and quality of life in PD patients.
Article
Urology & Nephrology
Mihran Naljayan, Abigail Hunt, Katherine McKeon, Gilbert Marlowe, Martin J. Schreiber, Steven M. Brunelli, Francesca Tentori
Summary: This study assessed the associations between incremental peritoneal dialysis use and clinical outcomes and quality of life measures in a large cohort of incident peritoneal dialysis patients in the US. The results show that among continuous ambulatory peritoneal dialysis patients, incremental peritoneal dialysis use was associated with better quality of life and lower hospitalization and mortality rates.
JOURNAL OF NEPHROLOGY
(2023)
Article
Urology & Nephrology
Mihran Naljayan, Abigail Hunt, Katherine Mckeon, Gilbert Marlowe, Martin J. Schreiber, Steven M. Brunelli, Francesca Tentori
Summary: This study assessed the associations between incremental peritoneal dialysis use and clinical outcomes and quality of life measures in a large cohort of incident peritoneal dialysis patients in the US. The results showed that incremental peritoneal dialysis use was associated with better quality of life scores in three domains for continuous ambulatory peritoneal dialysis patients. However, no significant effects of incremental peritoneal dialysis were observed in patients initiating automated peritoneal dialysis.
JOURNAL OF NEPHROLOGY
(2023)
Article
Pediatrics
Yifan Zhang, Talia Gutman, Allison Tong, Jonathan C. Craig, Aditi Sinha, Allison Dart, Allison A. Eddy, Debbie S. Gipson, Detlef Bockenhauer, Hui-Kim Yap, Jaap Groothoff, Michael Zappitelli, Nicholas J.A.Webb, Stephen I. Alexander, Susan Furth, Susan Samuel, Tom D. Blydt-Hansen, Janis Dionne, Mini Michael, Scott E. Wenderfer, Wolfgang C. Winkelmayer, Steven McTaggart, Amanda Walker, Cortney T. Zimmerman, Angelique F. Ralph, Angela Ju, Laura J. James, Camilla S. Hanson
Summary: Children with chronic kidney disease and their caregivers face numerous barriers in accessing psychosocial and educational support, leading to feelings of disempowerment and isolation. Improved availability and access to psychosocial and educational interventions are needed to enhance the well-being and educational advancement of these children.
PEDIATRIC NEPHROLOGY
(2023)
Article
Immunology
Eric H. K. Au, Jeremy R. Chapman, Armando Teixeira-Pinto, Jonathan C. Craig, Germaine Wong
Summary: In kidney transplant recipients, cancer incidence and mortality are highest during periods with a functioning graft and remain higher than in the general population even after graft loss.
Review
Health Policy & Services
K. J. Mrklas, J. M. Boyd, S. Shergill, S. Merali, M. Khan, L. Nowell, A. Goertzen, L. M. Pfadenhauer, K. Paul, K. M. Sibley, L. Swain, M. Vis-Dunbar, M. D. Hill, S. Raffin-Bouchal, M. Tonelli, I. D. Graham
Summary: The objective of this study was to identify and assess valid, reliable, and acceptable tools for evaluating outcomes and impacts of health research partnerships worldwide. A total of 48 studies and 58 tools were analyzed, with most tools consisting of surveys, questionnaires, and scales. While many tools had empirical validity, there were inconsistencies in the assessment and reporting of psychometric characteristics. The study also identified a subset of tools with empirical evidence, pragmatic strength, and moderate study quality.
HEALTH RESEARCH POLICY AND SYSTEMS
(2023)
Editorial Material
Urology & Nephrology
Bruno Ranchin, Claus Peter Schmitt, Bradley Warady, Jonathan C. Craig, Christoph Licht, Hiroshi Hataya, Enrico Vidal, Johan Vande Walle, Rukshana Shroff
KIDNEY INTERNATIONAL
(2023)
Article
Urology & Nephrology
Nicole Scholes-Robertson, Katrina Blazek, Allison Tong, Talia Gutman, Jonathan C. Craig, Beverley M. Essue, Kirsten Howard, Germaine Wong, Martin Howell
Summary: This study aims to quantify the financial impact and out-of-pocket expenditure of rural adult patients with chronic kidney disease (CKD) in Australia. The survey results showed that the mean out-of-pocket expenses were 5056 AUD annually, and 78% of households experienced financial hardship, with 54% classified as experiencing financial catastrophe. Additionally, some participants had to relocate for a period greater than 3 months to access care, raising concerns about equity in Australia.
Article
Medicine, General & Internal
Andrea Matus Gonzalez, Eduardo Lorca, Sebastian Cabrera, Alejandra Hernandez, Carlos Zuniga-SM, Laura Sola, Luis Michea, Alejandro Ferreiro Fuentes, Lilia Cervantes, Magdalena Madero, Armando Teixeira-Pinto, Germaine Wong, Jonathan Craig, Allison Jaure
Summary: Nephrologists in Latin America faced personal and professional vulnerability while caring for patients undergoing regular hemodialysis during the COVID-19 pandemic. They reported feeling helpless and morally distressed, doubting their ability to provide safe care. Better availability and adaptation of care models, including telehealth and home-based dialysis, are urgently needed.
Review
Economics
Joseph Kwon, Sarah Smith, Rakhee Raghunandan, Martin Howell, Elisabeth Huynh, Sungwook Kim, Thomas Bentley, Nia Roberts, Emily Lancsar, Kirsten Howard, Germaine Wong, Jonathan Craig, Stavros Petrou
Summary: This study conducted a systematic review of psychometric evidence for generic childhood MAUIs and provides comprehensive evidence on their performance. It assists in selecting instruments based on scientific rigor and identifies gaps and methodological issues for future research.
APPLIED HEALTH ECONOMICS AND HEALTH POLICY
(2023)
Review
Endocrinology & Metabolism
Patrizia Natale, Sharon Chen, Clara K. Chow, Ngai Wah Cheung, David Martinez-Martin, Corinne Caillaud, Nicole Scholes-Robertson, Ayano Kelly, Jonathan C. Craig, Giovanni Strippoli, Allison Jaure
Summary: Continuous glucose monitoring (CGM) can improve self-management and confidence in patients managing diabetes. However, technical issues, uncertainty in readings, and cost may limit its uptake. Education and training from health professionals may help reduce the practical and psychological burden for better patient outcomes.
JOURNAL OF DIABETES
(2023)
Article
Medicine, General & Internal
Marcello Tonelli, Natasha Wiebe, Meg Lunney, Maoliosa Donald, Tanis Howarth, Julie Evans, Scott W. Klarenbach, David Nicholas, Tiffany Boulton, Stephanie Thompson, Kara Schick Makaroff, Braden Manns, Brenda Hemmelgarn
Summary: Hearing loss is a common disability worldwide and is associated with a wide range of adverse clinical outcomes. This population-based cohort study in Alberta, Canada, found that individuals with hearing loss had higher rates of hospitalization, falls, adverse drug events, and emergency visits compared to those without hearing loss. They also had increased risks of death, cardiovascular events, depression, dementia, and other health issues.
Review
Medicine, General & Internal
Edmund Y. M. Chung, Suetonia C. Palmer, Valeria M. Saglimbene, Jonathan C. Craig, Marcello Tonelli, Giovanni F. M. Strippoli
Summary: This update of the Cochrane review found that erythropoiesis-stimulating agents (ESAs) may be more effective than placebo in treating anaemia in patients with chronic kidney disease, but their use may also increase the risk of cardiovascular events and hypertension. The comparative effects of different ESAs and their effects on other outcomes such as cardiovascular death and kidney failure remain uncertain.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS
(2023)
Review
Medicine, General & Internal
Deirdre Hahn, Elisabeth M. Hodson, Jonathan C. Craig
Summary: This article is a review study on IgA vasculitis. The study found that the use of corticosteroids or antiplatelet agents may have little or no benefit in preventing kidney disease in children with IgAV. MMF or tacrolimus may be less effective in treating severe IgAV-associated kidney disease compared to IV cyclophosphamide, but with fewer adverse effects. The efficacy of cyclosporin, MMF, or leflunomide in the treatment of severe IgAV-associated kidney disease in children remains unclear.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS
(2023)
Review
Economics
Tessa Peasgood, Martin Howell, Rakhee Raghunandan, Amber Salisbury, Marcus Sellars, Gang Chen, Joanna Coast, Jonathan C. Craig, Nancy J. Devlin, Kirsten Howard, Emily Lancsar, Stavros Petrou, Julie Ratcliffe, Rosalie Viney, Germaine Wong, Richard Norman, Cam Donaldson
Summary: This study aimed to synthesize knowledge on the social value of child and adult health and found that the majority of studies supported prioritizing children. However, not all studies were consistent with this view, and there are research gaps in understanding the value of health gains for very young children and the motivations behind the public's views.
Meeting Abstract
Urology & Nephrology
Siah Kim, Anita Van Zwieten, Chandana Guha, Rabia Khalid, Madeleine Didsbury, Anna Francis, Steven Mctaggart, Fiona Mackie, Chanel Prestidge, Armando Teixeira-Pinto, Kirsten Howard, Natasha Nassar, Allison Jaure, Jonathan C. Craig, Germaine Wong
Meeting Abstract
Urology & Nephrology
Adela Yip, Brydee Cashmore, Adam Mullan, Alex Currie, Chandana Guha, Hicham C. Hassan, Ieuan Wickham, Lyn Lloyd, Martin Howell, Matthew Jose, Nicole Scholes-Robertson, Jonathan C. Craig, Allison Jaure, David J. Tunnicliffe