Article
Cardiac & Cardiovascular Systems
Karsten Konigstein, Julia Charlotte Buschges, Giselle Sarganas, Susanne Krug, Hannelore Neuhauser, Arno Schmidt-Trucksass
Summary: This study found that exercise can reduce cardiovascular risk in young individuals, but has little effect on carotid structure and function.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Massimo R. Mannarino, Matteo Pirro, Bruna Gigante, Kai Savonen, Sudhir Kurl, Philippe Giral, Andries Smit, Fabrizio Veglia, Elena Tremoli, Damiano Baldassarre
Summary: The study found a U-shaped association between SUA levels and VEs in men at moderate-to-high CVD risk, with both low and high SUA levels being associated with an increased risk of VEs. Elevated SUA levels were also independently associated with cIMT progression in men. However, no significant associations were found in women between SUA levels, CVD end points, and cIMT progression.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2021)
Article
Cardiac & Cardiovascular Systems
Panagiotis Theofilis, Evangelos Oikonomou, George Lazaros, Georgia Vogiatzi, Maria Anastasiou, Vasiliki Chara Mystakidi, Athina Goliopoulou, Evangelia Christoforatou, Evgenia Bourouki, Georgia Vavouranaki, Georgios Marinos, Dimitris Tousoulis
Summary: This study evaluated arterial stiffness and carotid atherosclerotic burden in patients with diabetes mellitus (DM). The results showed that individuals with DM had increased intima-media thickness, carotid plaque burden, and carotid-to-femoral pulse wave velocity compared to those without DM. These findings indicate a higher risk of future cardiovascular events associated with DM.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
(2022)
Article
Endocrinology & Metabolism
J. J. Drinkwater, F. K. Chen, A. M. Brooks, B. T. Davis, A. W. Turner, T. M. E. Davis, W. A. Davis
Summary: This study found an independent association between macrovascular disease and arterial stiffness with diabetic retinopathy in patients with type 2 diabetes. The occurrence of diabetic retinopathy is closely related to patients' age at diagnosis, blood glucose control level, treatment method, and cardiovascular health.
Article
Endocrinology & Metabolism
Wei Li, Yan Wang, Shengrong Ouyang, Mengdi Li, Rui Liu, Yuqi Zhang, Xiaojun Liu, Tianfang Li, Shengyun Liu
Summary: In patients with type 2 diabetes mellitus, elevated serum uric acid levels are closely associated with metabolic syndrome and its components, but not with carotid atherosclerosis.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Review
Cardiac & Cardiovascular Systems
Maria M. Pereira, Juan Torrado, Claudio Sosa, Yanina Zocalo, Daniel Bia
Summary: Preeclampsia is a serious pregnancy complication with potential origins in maternal cardiovascular maladaptation rather than just placental dysfunction. While a majority of cases may be related to abnormal placentation, not all affected women fit the placental hypothesis. Recent research suggests that arterial biomechanics play a significant role in preeclampsia pathophysiology, impacting maternal heart function and fetal-placental circulation.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
(2021)
Article
Biology
Eva Anna Piros, Akos Szabo, Fanni Rencz, Valentin Brodszky, Klara Szalai, Noemi Galajda, Balint Szilveszter, Edit Dosa, Bela Merkely, Peter Hollo
Summary: In this study, IL-17 inhibitor therapy was found to significantly improve the condition of severe psoriatic patients, reducing both physical and psychological burden. Furthermore, the arterial intima-media thickness showed significant improvement during the treatment process, suggesting a potential protective effect on cardiovascular complications.
Article
Endocrinology & Metabolism
Monica Simina Mihuta, Corina Paul, Andreea Borlea, Cristina Mihaela Roi, Denisa Pescari, Oana-Alexandra Velea-Barta, Ioana Mozos, Dana Stoian
Summary: Childhood obesity is associated with early subclinical atherosclerosis and arterial stiffness. Elevated levels of TMAO are observed in obese children, and TMAO is found to be positively correlated with BMI, waist circumference, and waist-to-height ratio. TMAO independently predicts CIMT, PWV, peripheral BP, and central SBP levels.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Peripheral Vascular Disease
Kazuki Shiina, Hirofumi Tomiyama, Atsushi Tanaka, Hisako Yoshida, Kazuo Eguchi, Kazuomi Kario, Toru Kato, Hiroki Teragawa, Shigeru Toyoda, Mitsuru Ohishi, Yoshihiro Fukumoto, Bonpei Takase, Tomoko Ishizu, Koichi Node
Summary: This study analyzed the long-term effects of febuxostat on atherosclerosis and arterial stiffness. The results showed that febuxostat treatment group had greater decrease in arterial stiffness parameters and serum uric acid compared to the control group. Therefore, long-term treatment with febuxostat may have beneficial effects on arterial stiffness without improving carotid atherosclerosis.
HYPERTENSION RESEARCH
(2022)
Article
Physics, Applied
Yoshifumi Nagai, Shohei Mori, Mototaka Arakawa, Hiroshi Kanai
Summary: The thickness of the carotid arterial wall obtained from B-mode imaging using ultrasonic diagnostic devices is widely used for the diagnosis of atherosclerosis. However, the measurement interval in the lateral direction of the B-mode image is limited by the beam interval, leading to a discrete image that cannot reflect local and minute thickness changes. A novel method is proposed to measure the roughness of the luminal surface by measuring the displacement of the carotid arterial wall in the lateral direction during one heartbeat, enabling a smoother measurement of the luminal surface and accurate assessment of local and minute thicknesses.
JAPANESE JOURNAL OF APPLIED PHYSICS
(2023)
Article
Cardiac & Cardiovascular Systems
Lisa Baumgartner, Heidi Weberruss, Tobias Engl, Thorsten Schulz, Renate Oberhoffer-Fritz
Summary: The study revealed that training duration and intensity were associated with vascular structure and function in children and adolescents, with higher intensity training contributing to thicker cIMT but also increased vascular elasticity.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Endocrinology & Metabolism
Yuanyuan Gao, Baofeng Xu, Yanyan Yang, Mei Zhang, Tian Yu, Qiujuan Zhang, Jianwei Sun, Rui Liu
Summary: This study analyzed the correlation between serum uric acid (SUA) levels and carotid intima-media thickness (CIMT) and explored the relationship between SUA and carotid atherosclerosis in different glucose metabolism patterns. The results showed that SUA was closely associated with an increase in CIMT and may be an independent risk factor for carotid atherosclerosis.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Pediatrics
Visnja Tokic Pivac, Vesna Herceg-Cavrak, Iva Hojsak, Zrinjka Misak, Oleg Jadresin, Sanja Kolacek
Summary: This study aimed to evaluate arterial parameters in pediatric IBD patients. The results showed that children with IBD have increased heart rate, altered pulse waveform, but normal arterial stiffness and carotid intima-media thickness.
EUROPEAN JOURNAL OF PEDIATRICS
(2023)
Article
Multidisciplinary Sciences
Gustavo Lara Rezende, Leonel Alves Oliveira, Renata Oliveira Soares, Fabiana Pirani Carneiro, Marcio Nakanishi, Sonia Nair Bao, Andre Luiz Lopes Sampaio, Selma Aparecida Souza Kuckelhaus
Summary: This study demonstrates that arterial hypertension may cause structural lesions in the vascular layers, increasing the risk of vascular rupture. The histology of the microvasculature associated with the mucosa of the posterior nasal cavity shows changes related to hypertension, which may be particularly significant during hypertensive peaks.
SCIENTIFIC REPORTS
(2022)
Review
Medicine, General & Internal
Hao Wu, Meihua Xu, Hong Hao, Michael A. Hill, Canxia Xu, Zhenguo Liu
Summary: Patients with inflammatory bowel disease (IBD) exhibit significant endothelial dysfunction, increased arterial stiffness, and carotid intima-media thickness (cIMT). Thus, patients with IBD may benefit from aggressive risk stratification for cardiovascular diseases.
JOURNAL OF CLINICAL MEDICINE
(2022)