期刊
JOURNALS OF GERONTOLOGY SERIES B-PSYCHOLOGICAL SCIENCES AND SOCIAL SCIENCES
卷 64, 期 5, 页码 577-585出版社
OXFORD UNIV PRESS INC
DOI: 10.1093/geronb/gbp061
关键词
ACTIVE; Depression; Randomized controlled trial; Speed of processing
资金
- ACTIVE Cognitive Training Trial
- National Institutes of Health
- Hebrew Senior-Life [NR04507]
- Indiana University [NR04508]
- Johns Hopkins University [AG14260]
- New England Research Institutes [AG14282]
- Pennsylvania State University [AG14263]
- University of Alabama at Birmingham [AG 14289]
- University of Florida [AGO 14276]
- Posit Science Corporation
- Center for Research in the Implementation of Innovative Strategies in Practice at the Iowa City VAMC
- Department of Veterans Affairs
- Veterans Health Administration
- Health Services Research and Development Service [HFP 04-149]
- NATIONAL INSTITUTE OF NURSING RESEARCH [U01NR004507, U01NR004508] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE ON AGING [U01AG014263, U01AG014289, U01AG014260, U01AG014276, U01AG014282] Funding Source: NIH RePORTER
We evaluated the effects or the 3 cognitive interventions fielded in the Advanced Cognitive Training for Independent and Vital Elderly study on 2 subsets of participants-1,606 without and 424 with suspected clinical depression at baseline. In the former group, only the speed of processing (vs. no-contact control) intervention had a significant effect, with its participants being 38% less likely to develop suspected clinical depression at I year (adjusted odds ratio = 0.62;p <.01). None of the interventions had a significant effect on recovery from suspected clinical depression in the latter group. Although the etiological mechanism of the speed of processing's protective effect was not isolated, it may result from successful adaptation to age-related changes through selective optimization with compensation.
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