Article
Geriatrics & Gerontology
Alexandra Cours, Mei-Hua Huang, Howard Fink, Kristine E. Ensrud, John T. Schousboe, Wendy Katzman, Diane Schneider, Nancy E. Lane, Peggy Cawthon, Deborah M. Kado
Summary: This study found that increasing blocks-measured kyphosis is associated with a higher risk of mortality in older men, indicating that hyperkyphosis should be considered as a clinically significant problem.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
(2023)
Article
Geriatrics & Gerontology
Yoshimi Fukuoka, Wendy B. Katzman, Amy Gladin, Nancy E. Lane, Jung Oh Yoo
Summary: Age-related hyperkyphosis is associated with adverse health outcomes. This study investigated the independent association between the degree of hyperkyphosis curvature and the 6-minute walk test (6MWT) distance in older adults. The results showed that the degree of hyperkyphosis curvature was not independently associated with the 6MWT distance, but taller height, lighter weight, and less prescription medication were significant predictors of better performance on the 6MWT distance.
Article
Endocrinology & Metabolism
Marije C. Koele, Hanna C. Willems, Karin M. A. Swart, Suzanne C. van Dijk, Paul Lips, Lisette C. P. G. M. de Groot, Tischa J. M. van der Cammen, M. Carola Zillikens, Natasja M. van Schoor, Nathalie van der Velde
Summary: Hyperkyphosis, an increased kyphosis angle of the thoracic spine, was associated with a higher fall incidence in the oldest quartile of a large prospective cohort of community-dwelling older adults. This suggests that hyperkyphosis may be a contributing factor to falls, especially in the oldest age group.
OSTEOPOROSIS INTERNATIONAL
(2022)
Review
Orthopedics
Mattia Zappala, Stephen Lightbourne, Nicola R. Heneghan
Summary: The study revealed a positive moderate correlation between thoracic kyphosis and age, with significant differences between different age groups. People often have kyphosis exceeding 40 degrees, and ethnicity seems to influence thoracic kyphosis, while gender differences are minimal.
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
(2021)
Article
Orthopedics
Yoshimi Fukuoka, Wendy B. Katzman, Amy Gladin, Nancy E. Lane, Deborah M. Kado, Yoo Jung Oh
Summary: This study aimed to determine if hyperkyphosis and upper extremity tasks were independently associated with the 6-minute walk test in older adults. The results showed that while hyperkyphosis was not associated with the walk test, timed tests of upper extremity function indicated that upper body dynamics can affect walking performance. Additionally, sociodemographic factors and the number of prescribed medications were significant contributors to the walk test in older adults with mild to moderate hyperkyphosis.
BMC MUSCULOSKELETAL DISORDERS
(2022)
Article
Geriatrics & Gerontology
Amy Gladin, Wendy B. Katzman, Yoshimi Fukuoka, Neeta Parimi, Shirley Wong, Nancy E. Lane
Summary: The study found that older adults with low physical function and hyperkyphosis may improve physical function after a targeted high-intensity kyphosis exercise and posture training intervention. Additionally, older adults with low physical function can safely participate in such interventions.
Article
Orthopedics
Nanniphada Chankavee, Sugalya Amatachaya, Torkamol Hunsawong, Thiwabhorn Thaweewannakij, Lugkana Mato
Summary: This research investigated the effects of a modified long stick exercise on hyperkyphosis, muscle imbalance, and balance control in elderly community-dwelling women with hyperkyphosis. The results showed that the experimental group demonstrated improvements in all outcomes, with significantly greater improvements compared to the control group.
JOURNAL OF BACK AND MUSCULOSKELETAL REHABILITATION
(2023)
Article
Multidisciplinary Sciences
Kazuhiro Hira, Keiji Nagata, Hiroshi Hashizume, Yoshiki Asai, Hiroyuki Oka, Shunji Tsutsui, Masanari Takami, Hiroshi Iwasaki, Shigeyuki Muraki, Toru Akune, Toshiko Iidaka, Hiroshi Kawaguchi, Kozo Nakamura, Munehito Yoshida, Sakae Tanaka, Noriko Yoshimura, Hiroshi Yamada
Summary: The study found a relationship between sagittal spinal malalignment and low back pain, with older participants having higher C7 SVA values, higher prevalence of LBP, and decreased physical performance. Multiple linear regression analysis showed that LBP and physical performance were significantly associated with C7 SVA.
SCIENTIFIC REPORTS
(2021)
Article
Geriatrics & Gerontology
Samaneh Farsijani, Adam J. Santanasto, Iva Miljkovic, Robert M. Boudreau, Bret H. Goodpaster, Stephen B. Kritchevsky, Anne B. Newman
Summary: The study found that the association between intermuscular fat area and impaired physical function is more significant in individuals with higher muscle area. This suggests that muscle mass plays a moderating role in the relationship between muscle fat deposition and physical performance.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2021)
Review
Pharmacology & Pharmacy
Khaled Nasser Almujel, Abdalah Emad Almhmd, Abdulrahman Arshed N. Alharfy, Ibrahim Abdullah Said Albalawi, Tariq Bander F. Alanazi, Aysha Jaber Alshehri, Bedour Eid H. Alatawi, Abdullah Dhafer Alshehri, Meshari Salman Alhawiti, Shumoukh Homoud Alshehri
Summary: Hyperkyphosis, identified by an excessive kyphosis angle, increases with age and is associated with a range of adverse health outcomes, such as worsening physical function and earlier mortality.
JOURNAL OF PHARMACEUTICAL RESEARCH INTERNATIONAL
(2021)
Article
Geriatrics & Gerontology
Wendy B. Katzman, Neeta Parimi, Amy Gladin, Shirley Wong, Nancy E. Lane
Summary: The study evaluated the long-term efficacy of a short-term kyphosis exercise and posture training intervention in older adults with hyperkyphosis. It found that kyphosis did not progress as expected with aging after the intervention, and there was an improvement in lordosis. However, there were declines in certain physical function and health-related quality of life measures.
JOURNAL OF GERIATRIC PHYSICAL THERAPY
(2021)
Article
Geriatrics & Gerontology
E. Peyrusque, J. Granet, B. Pageaux, F. Buckinx, M. Aubertin-Leheudre
Summary: The study found that fast walking speed, unipodal balance, normal walking speed, and normal Timed-Up and Go test were highly reliable in remote assessment conditions, while fast Timed-Up and Go test, Sit-to-Stand function, muscle endurance, and power were extremely reliable. In terms of absolute reliability, the standard error of measurement ranged from 15.54% to 5.14%. The minimal detectable change ranged from 43.07% to 14.21%.
JOURNAL OF NUTRITION HEALTH & AGING
(2022)
Article
Engineering, Biomedical
Sung-hoon Jung, Ui-jae Hwang, Jun-Hee Kim, Gyeong-Tae Gwak, Oh-yun Kwon
Summary: The study found that thoracic mobilization for eight weeks significantly improved thoracic hyperkyphosis and forward shoulder posture. Patients with a kyphosis change ratio greater than 13.79% were more likely to improve their forward shoulder posture.
CLINICAL BIOMECHANICS
(2022)
Article
Health Care Sciences & Services
Yi-Hung Huang, I-Yao Fang, Yi-Liang Kuo
Summary: The study found that Nordic walking has limited influence on age-related hyperkyphosis and back pain, but may be effective for improving physical function. Among the seven clinical tests of physical function, only the 30 s arm curl test, the 30 s chair stand test, and the single leg stance test showed significant improvements.
Article
Public, Environmental & Occupational Health
Vivian Castillo de Lima, Luz Albany Arcila Castano, Ricardo Aurelio Carvalho Sampaio, Priscila Yukari Sewo Sampaio, Camila Vieira Ligo Teixeira, Marco Carlos Uchida
Summary: Agility training is essential for improving neuromuscular performance and balance in older adults. This study examined the physical and cognitive effects of an agility ladder training program on healthy older adults. The results showed that only the group that received cognitive training alongside agility training showed improvements in cognitive function, while the group that only performed agility training saw improvements in physical performance.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Geriatrics & Gerontology
Mary E. Winger, Paolo Caserotti, Jane A. Cauley, Robert M. Boudreau, Sara R. Piva, Peggy M. Cawthon, Eric S. Orwoll, Kristine E. Ensrud, Deborah M. Kado, Elsa S. Strotmeyer
Summary: This study investigated the application of lower-extremity power and upper-extremity strength in fall injuries and found that lower leg power and grip strength predicted future fall injury risk in older men, independent of physical performance.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2023)
Article
Geriatrics & Gerontology
Lisa Langsetmo, John T. Schousboe, Brent C. Taylor, Jane A. Cauley, Howard A. Fink, Peggy M. Cawthon, Marcia L. Stefanick, Deborah M. Kado, Allyson M. Kats, Kristine E. Ensrud
Summary: This study evaluated the risks of clinical fracture, hip fracture, and mortality prior to fracture among men aged at least 80 years. The results showed that fall history, hip bone mineral density, and recent fracture were strong predictors of clinical fracture and hip fracture. Age and multimorbidity were strong predictors of mortality before fracture. The study results have important implications for guiding osteoporosis drug treatment decisions.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2023)
Article
Geriatrics & Gerontology
Alexandra Cours, Mei-Hua Huang, Howard Fink, Kristine E. Ensrud, John T. Schousboe, Wendy Katzman, Diane Schneider, Nancy E. Lane, Peggy Cawthon, Deborah M. Kado
Summary: This study found that increasing blocks-measured kyphosis is associated with a higher risk of mortality in older men, indicating that hyperkyphosis should be considered as a clinically significant problem.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
(2023)
Review
Geriatrics & Gerontology
Mehrbod Estaki, Lisa Langsetmo, Michelle Shardell, Anna Mischel, Lingjing Jiang, Yuan Zhong, Christopher Kaufmann, Rob Knight, Katie Stone, Deborah Kado
Summary: Growing evidence suggests bidirectional links between gut microbiota and sleep quality as shared contributors to health. However, little is known about the relationship between microbiota and sleep among older persons. This study analyzed stool microbiota and sleep quality among older men, and found that men with poor sleep tended to have lower microbiota diversity and that sleep regularity was significantly associated with microbiota composition.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2023)
Article
Endocrinology & Metabolism
Margaret P. Seaton, Jeanne F. Nichols, Mitchell J. Rauh, Deborah M. Kado, Julie Loebach Wetherell, Eric J. Lenze, David Wing
Summary: This study examined the associations between total body and trunk lean mass, maximal muscular strength, gait speed, and trabecular bone score (TBS) in 141 older adults. The results showed that upper body strength significantly predicted TBS, while total body lean mass index showed a trend in the expected direction.
JOURNAL OF CLINICAL DENSITOMETRY
(2023)
Article
Cardiac & Cardiovascular Systems
Ashok Krishnaswami, Michael W. Rich, Min Ji Kwak, Parag Goyal, Daniel E. Forman, Abdulla A. Damluji, Matthew Solomon, Jamal S. Rana, Deborah M. Kado, Michelle C. Odden
Summary: This study evaluated the impact of intensive hypertension treatment on mortality after non-fatal cardiovascular events. The results showed that intensive treatment reduced all-cause mortality, but the effect was attenuated when mediated through cardiovascular events and potentially harmful when mediated through serious adverse events.
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2023)
Article
Endocrinology & Metabolism
Paul C. Okoro, Eric S. Orwoll, Curtis Huttenhower, Xochitl Morgan, Thomas M. Kuntz, Lauren J. Mciver, Alyssa B. Dufour, Mary L. Bouxsein, Lisa Langsetmo, Samaneh Farsijani, Deborah M. Kado, Roberto Pacifici, Shivani Sahni, Douglas P. Kiel
Summary: The study found an association between the human gut microbiome and skeletal health, with the abundance of gut microbiota being related to bone measures.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Endocrinology & Metabolism
Lauren S. Roe, Stephanie Harrison, Peggy M. Cawthon, Kristine Ensrud, Kelley Pettee Gabriel, Deborah M. Kado, Jane A. Cauley
Summary: In addition to the volume of physical activity, frequent breaks from sedentary behavior and active bouts can reduce the risk of falls and fractures. A study found that there is a long-term relationship between the frequency of breaks from sedentary behavior and the occurrence of recurrent falls and fractures. The study also concluded that breaking up extended periods of sedentary time can reduce fall risk, regardless of the total sedentary time.
Article
Endocrinology & Metabolism
Lisa T. Langsetmo, John C. Schousboe, Brent A. Taylor, Jane A. Cauley, Howard M. Fink, Peggy M. Cawthon, Deborah E. Kado, Kristine Ensrud
Summary: Targeted fracture prevention strategies among late-life adults should consider both fracture risk and competing mortality risk. A machine learning method was used to evaluate risk factors and create models for hip fractures and competing mortality among adults aged 80 years and older. Random forest models were compared to Fine-Gray models with six variables. Top variables for predicting hip fractures were bone mineral density, while frailty was associated with competing mortality. Random forest models performed slightly better than Fine-Gray models for predicting mortality, but similarly for predicting hip fractures.
Meeting Abstract
Endocrinology & Metabolism
Kristine Ensrud, John Schousboe, Howard Fink, William Leslie, Brent Taylor, Peggy Cawthon, Deborah Kado, Nancy Lane, Carolyn Crandall, Jane Cauley, Lisa Langsetmo
JOURNAL OF BONE AND MINERAL RESEARCH
(2023)
Meeting Abstract
Endocrinology & Metabolism
Tiffany Kim, Trisha Hue, Susan Ewing, Xiaojuan Li, Sigurour Sigurosson, Vilmundur Guonason, Annegreet Velduis-Vlug, Deborah Kado, Eric Vittinghoff, Karin Wu, Eileen Koh, Clifford Rosen, Mone Zaidi, Ann Schwartz, Anne Schafer
JOURNAL OF BONE AND MINERAL RESEARCH
(2023)
Meeting Abstract
Endocrinology & Metabolism
Lisa Langsetmo, John T. Schousboe, Brent C. Taylor, Jane A. Cauley, Howard A. Fink, Peggy M. Cawthon, Marcia L. Stefanick, Deborah M. Kado, Kristine E. Ensrud
JOURNAL OF BONE AND MINERAL RESEARCH
(2023)
Meeting Abstract
Endocrinology & Metabolism
John Schousboe, Lisa Langsetmo, Howard Fink, Deborah Kado, Jane Cauley, Brent Taylor, Kristine Ensrud
JOURNAL OF BONE AND MINERAL RESEARCH
(2023)
Meeting Abstract
Urology & Nephrology
Julia H. Yuan, Dena E. Rifkin, Charles Ginsberg, Peggy Cawthon, Deborah M. Kado, Scott R. Bauer, Kristine Ensrud, Andrew Hoffman, O. Alison Potok
AMERICAN JOURNAL OF KIDNEY DISEASES
(2023)
Article
Rheumatology
Karen Y. Cheng, Elsa S. Strotmeyer, Deborah M. Kado, John T. Schousboe, Simon Schenk, Michael Nevitt, Nancy E. Lane, Jan M. Hughes-Austin
Summary: Metabolic syndrome (MetS) was associated with hip osteoarthritis (OA) in women, while obesity was associated with hip OA in men. These findings suggest different mechanisms of hip OA development in men and women.
ACR OPEN RHEUMATOLOGY
(2023)