Article
Multidisciplinary Sciences
Jiabin Shu, Xiao Ma, Hua Ma, Qiurong Huang, Ye Zhang, Mei Guan, Chunyun Guan
Summary: This study reveals the response mechanism of Brassica napus to salt stress through transcriptomics, metabolomics, and proteomics analysis. The key hormones, Abscisic acid (ABA) and jasmonic acid (JA), were found to play a crucial role in the response to salt stress. Salt stress for 24 hours is a crucial time point, during which Brassica napus adjusts multiple pathways to avoid over-reaction and energy consumption. Additionally, certain metabolites and proteins are important for maintaining the balance of ROS and responding to salt stress.
Article
Microbiology
Md Tabibul Islam, Bok-Rye Lee, Van Hien La, Dong-Won Bae, Woo-Jin Jung, Tae-Hwan Kim
Summary: The study investigated the response proteins of susceptible and resistant cultivars of Brassica napus to Xanthomonas campestris pv. campestris using gel-free quantitative proteomics. The results showed significant differences in protein expression between the two cultivars, with the resistant cultivar exhibiting more pronounced upregulation of redox-related and innate immunity-related proteins.
Review
Plant Sciences
M. Ashraf
Summary: Improving thermotolerance in plants requires precise selection criteria based on physiological, biochemical, and molecular processes, rather than solely focusing on yield attributes. Understanding the specific genes involved in stress tolerance is crucial for successful breeding programs and gene editing using advanced techniques.
ENVIRONMENTAL AND EXPERIMENTAL BOTANY
(2021)
Article
Physiology
Yudong Quan, Zhenying Wang, Hongyi Wei, Kanglai He
Summary: The relationship between heat acclimation and the expression of specific HSPs plays a critical role in insect adaptation and evolution. Extreme thermal stress induces quick onset of HSP70 or HSP90 transcription, potentially aiding in adaptation to drastic temperature variations. Furthermore, the thermal tolerance of larvae is significantly enhanced after 6 hours of recovery, possibly regulated by HSP70.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Plant Sciences
Neeta Lohani, Mohan B. Singh, Prem L. Bhalla
Summary: Increases in extreme temperature events caused by climate change negatively affect agricultural productivity and global food security. New research has found that in high temperatures, oilseed rape anthers undergo rapid transcriptional reprogramming to respond to the unfolded protein response. Additionally, the study found that heat stress can activate the cytosolic heat response network. These findings shed light on the early stress-responsive mechanisms in plant cells.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Biochemistry & Molecular Biology
Natasa Bauer, Mirta Tkalec, Nikola Major, Ana Talanga Vasari, Mirta Toki, Sandra Vitko, Dean Ban, Smiljana Goreta Ban, Branka Salopek-Sondi
Summary: Rising temperatures and drought are negatively impacting biodiversity and agricultural productivity. In this study, the responses of 33 kale accessions to individual and combined stress were evaluated. The most tolerant accessions showed higher basal content of stress-related compounds and increased expression of stress-related genes.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Plant Sciences
Maria Tortosa, Pablo Velasco, Victor Manuel Rodriguez, Maria Elena Cartea
Summary: Understanding plant's response mechanisms against pathogenesis is fundamental for resistant crop development. This study compared the proteomes of Brassica oleracea leaves infected with Xanthomonas campestris pv. campestris at different post-infection times. The results revealed that different cell processes, including primary metabolism, hormone signaling, and defense mechanisms, were involved in the plant's response to infection.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Environmental Sciences
Yu-Cheng Wang, Ya-Wen Chang, Jing Bai, Xiao-Xiang Zhang, Junaid Iqbal, Ming-Xing Lu, Wei-Rong Gong, Yu-Zhou Du
Summary: The leafminer fly Liriomyza trifolii exhibits adaptive cross-tolerance to high temperature and abamectin, which can ultimately reduce the overuse of pesticides.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Article
Cell & Tissue Engineering
Ju-Fang Liu, Po-Chun Chen, Thai-Yen Ling, Chun-Han Hou
Summary: This study demonstrates that heat shock induces the expression of HSPs in hPDMCs through the activation of ROS, p38 MAPK, Akt signaling, and HSF1, which plays a protective role.
STEM CELL RESEARCH & THERAPY
(2022)
Review
Cell Biology
Ariadni Androvitsanea, Kostas Stylianou, Eleni Drosataki, Ioannis Petrakis
Summary: Research has shown that heat-shock proteins can have varying effects on the immune system, either triggering immune responses or alleviating them, which is important for studying and treating autoimmune diseases.
Article
Biochemistry & Molecular Biology
Faith O. Alele, John R. Otto, Bunmi S. Malau-Aduli, Aduli E. O. Malau-Aduli
Summary: This pilot study found an association between a genetic variant in the HSPA1B gene at the g.31829044 locus and heat tolerance among Australian Defence Force members with a history of exertional heat stroke.
Article
Plant Sciences
Ambreen Mehvish, Abdul Aziz, Birra Bukhari, Humaira Qayyum, Zahid Mahmood, Muhammad Baber, Muhammad Sajjad, Xuequn Pang, Fenglan Wang
Summary: This study identified 143 quantitative trait nucleotides (QTNs) associated with heat tolerance in synthetic hexaploid wheats (SHWs) through genome-wide association studies. In addition, 17 QTNs were found to be in proximity to heat shock proteins (HSPs), which may carry novel alleles for heat-tolerance genes.
Article
Cell Biology
Bryan E. Luu, Liam J. Hawkins, Kenneth B. Storey
Summary: Studies on dehydration tolerance have been mainly focused on plants and invertebrates, with vertebrate molecular mechanisms largely unexplored. This review highlights the physiological, cellular, and molecular responses of the African clawed frog to whole-body dehydration, showcasing adaptations such as water retention in vital organs, altered blood circulation, and activation of pro-survival pathways. The X. laevis genome research, in conjunction with ongoing studies, presents a promising avenue to delve deeper into the molecular adaptations for dehydration tolerance.
MOLECULAR AND CELLULAR BIOCHEMISTRY
(2021)
Article
Plant Sciences
Lu Lu, Sokrat G. Monakhos, Yong Pyo Lim, So Young Yi
Summary: The study identified significant differences in the expression of defense-related genes and antioxidant activity between black rot disease-resistant cabbage lines and susceptible lines, indicating a potential role for Xcc-induced reactive oxygen species in black rot disease development.
Article
Biotechnology & Applied Microbiology
Maxsueli Aparecida Moura Machado, Vinicius Silva Castro, Adelino da Cunha Neto, Ricardo Cesar Tavares Carvalho, Kim Stanford, Carlos Adam Conte-Junior, Eduardo Eustaquio de Souza Figueiredo
Summary: This study aimed to characterize Escherichia coli (E. coli) and shiga toxin-producing E. coli (STEC) isolates from Brazilian beef to determine their heat resistance and the presence of the transmissible locus of stress tolerance (tLST). Results showed that 3 out of 22 STEC isolates were heat resistant, 12 were moderately resistant, and 7 were sensitive to heat treatments. Whole genome sequencing (WGS) analysis revealed that the heat-resistant isolates carried tLST genes with high similarity to the homeostasis module genes in E. coli. However, no stx genes associated with tLST-positive isolates were found, although virulence and resistance genes were detected in extraintestinal pathogenic E. coli (ExPEC).
JOURNAL OF APPLIED MICROBIOLOGY
(2023)
Article
Environmental Sciences
Fenghua Li, Xianqi Zhao, Yanni Jiao, Xinglan Duan, Lianlong Yu, Fengjia Zheng, Xiaolin Wang, Lin Wang, Jia-Sheng Wang, Xiulan Zhao, Tianliang Zhang, Wei Li, Jun Zhou
Summary: This study analyzed the exposure level and health risks of aflatoxins (AFs) and zearalenone (ZEA) through cooking oil consumption in Shandong, China. The findings showed that children are facing the highest health risk, and liver cancer incidence is associated with exposure to aflatoxins.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Engineering, Electrical & Electronic
Dehui Wu, Shibin Lin, Hongfu Chen, Xiaohong Wang
Summary: An analytical model for calculating the mutual inductance between coplanar rectangular spiral coils was developed in this study. The model is applicable to PCB-based spiral coils in eddy-current testing probes and can simplify the calculation process while maintaining accuracy.
INTERNATIONAL JOURNAL OF NUMERICAL MODELLING-ELECTRONIC NETWORKS DEVICES AND FIELDS
(2023)
Article
Polymer Science
Xin-Xin Zhi, Hua-Sen Wang, Jie Jia, Xiao-Lei Wang, Yan-Shuang Ga, Shu-Jing Chen, Jin-Gang Liu
Summary: In this study, alignment agents derived from different poly(amic acid)s (PAAs) were prepared and applied to the fabrication of liquid crystal (LC) minicells. The polyimides (PI) alignment layers obtained from the thermal dehydration reaction of the PAA precursors showed good alignment effects to the LC molecules and exhibited good optoelectronic features.
POLYMERS FOR ADVANCED TECHNOLOGIES
(2023)
Article
Obstetrics & Gynecology
Linli Hu, Jieqiang Lv, Qianhong Ma, Xiujuan Chen, Xiaohong Wang, Xiaoyan Liang, Dingfei Xu, Yanping Li, Yuanhua Huang, Lina Hu, Xiaohui Deng, Jing Wei, Feng Zhou, Songying Zhang, Jie Wang, Fang Ma, Yingpu Sun
Summary: The study aimed to compare the equivalence of QL1012 and Gonal-f((R)) in ovarian stimulation for assisted reproductive technology. The results showed that there were no significant differences between QL1012 and Gonal-f((R)) in the primary endpoint of oocytes retrieved, and they had similar safety profiles.
REPRODUCTIVE BIOMEDICINE ONLINE
(2023)
Article
Psychiatry
Yu Gu, Huijuan Guo, Jiansong Zhou, Xiaoping Wang
Summary: This study investigated the socio-demographic, clinical, and offense-related characteristics of mentally ill offenders in a forensic psychiatric hospital in China. The majority of the participants were male, unmarried, and had sought medical help for their mental illnesses prior to their offenses. Schizophrenia was the most common diagnosis, and homicide offenses were prevalent, with family members being the most common victims.
Article
Biochemistry & Molecular Biology
Hao Liu, Jingxuan Wang, Mei Liu, Xia Zhang, Ying Liang, Jinshui Wang
Summary: Self-assembled fibrillation of wheat gluten is a common phenomenon in the production and processing of wheat flour products. The breakage of hydrogen bonds, strengthening of hydrophobic interactions, and SH-SS exchange reactions play important roles in fibrillation. Wheat gluten with higher degrees of hydrolysis show a greater propensity for worm-like aggregation.
Article
Genetics & Heredity
Liangcheng Yu, Lu Wang, Lijin Wang, Song Yan, Shuqiang Chen, Qian Xu, Danjie Su, Xiaohong Wang
Summary: This study aims to identify the association between immune cell types, immune-related genes, and recurrent implantation failure (RIF) through bioinformatics analysis. Differentially expressed genes (DEGs) were screened, and enrichment analysis and protein-protein interaction (PPI) analysis were conducted. The RIF-associated immune cell types were clarified, and differentially expressed immune cell types-related modules were identified. Three immune-related hub genes were identified and validated, and a ceRNA network was constructed.
FRONTIERS IN GENETICS
(2023)
Article
Chemistry, Medicinal
Baiyang Xu, Mengxue Yao, Zilu Liu, Shanshan Zhang, Bin Wang, Yanquan Han, Jiarong Gao, Deling Wu, Xiaoli Wang
Summary: The combination of Stephania tetrandra and Astragalus membranaceus has positive effects on the treatment of nephrotic syndrome by reducing renal injury and improving the condition. It achieves this by inhibiting the IL-13/STAT6 signal pathway, regulating endogenous metabolic pathways, and inhibiting the expression of AQP2 and AVP genes.
Article
Radiology, Nuclear Medicine & Medical Imaging
Xiaohong Wang, Guiying Du, Yao Liu
Summary: The study found that lateral meniscal body extrusion (LMBE) is associated with progression of OA-related knee structural damage over 4 years, and identified thresholds for predicting this progression.
EUROPEAN JOURNAL OF RADIOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Qiong Wang, Xiao-Hong Wang, Qing Pan, Hai Chang, Hong-Jian Yu, Wei-Qiang Pang
Summary: The thermal behaviors of nano-scale composite energetic materials composed of ADN and NC were studied using various instruments. The results showed that the interaction mechanism between ADN and NC is crucial for the design and safety of these materials. The mixture of NC and ADN exhibited different thermal decomposition characteristics compared to NC or ADN alone. ADN initiated the interaction with NC, leading to the formation of oxidative gases. The thermal decomposition process of ADN dominated the initial stage of the mixture, followed by the oxidation of NC and the cation of ADN.
Article
Immunology
Genwei Zhang, Guodong Niu, Diana Hooker-Romera, Sadeq Shabani, Julian Ramelow, Xiaohong Wang, Noah S. Butler, Anthony A. James, Jun Li
Summary: In this study, antibodies against human alpha-tubulin were found to significantly reduce the number of P. falciparum oocysts in mosquito midguts. Further investigation revealed that antibodies specifically against P. falciparum alpha-tubulin-1 also limited the transmission of P. falciparum to mosquitoes. Mouse monoclonal antibodies against recombinant P. falciparum alpha-tubulin-1 were generated, and two of them, A3 and A16, effectively blocked parasite transmission.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Lingze Yang, Lei Bao, Tong Dong, Honghao Xie, Xiaohong Wang, Huili Wang, Jingbo Wu, Chen Hao
Summary: In this study, Typha angustifolia was chemically modified with potassium permanganate to obtain modified Typha angustifolia (MTC), and then compounded with carboxymethyl cellulose (CMC) and guar gum (GG) to prepare the CMC/GG/MTC composite hydrogel. The optimal adsorption conditions were determined, and the maximum adsorption capacity for Cu2+, Co2+, and methylene blue (MB) were calculated. The results showed that the main mechanism of removing pollutants by the adsorbent is surface complexation and electrostatic attraction. The CMC/GG/MTC adsorbent exhibited good adsorption and regeneration capacity after five cycles.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Proceedings Paper
Energy & Fuels
Fan Yang, Xiaohong Wang, Haishan Guo, Hemin Yang, Zhixin Huo, Youzong Jian, Jing Hu
Summary: This paper proposes a direct AC-AC modular multilevel converter called Hexverter, which is based on cascaded full-bridge sub-modules and is suitable for connecting two systems operating at different frequencies. However, the operating range of Hexverter is limited by the capacitor voltage of the sub-modules. To address this issue, a strategy based on optimal neutral voltage and circulating current is proposed to limit the capacitor voltage within a specific range and minimize switching loss. Simulation results confirm that this strategy effectively suppresses the magnitude of the capacitor ripple voltage and reduces switching loss.
PROCEEDINGS OF THE 3RD INTERNATIONAL SYMPOSIUM ON NEW ENERGY AND ELECTRICAL TECHNOLOGY
(2023)
Review
Materials Science, Biomaterials
Dongxu Xu, Qian Duan, Hui Yu, Wenyue Dong
Summary: Porphyrins and their derivatives have excellent properties that make them attractive for various applications, but their limitations hinder their use in biomedicine. Metal-organic frameworks (MOFs) have emerged as a promising solution by combining the unique properties of porphyrins and MOFs. This article reviews the synthetic strategies and recent research achievements in forming porphyrin-based MOFs and their applications in photodynamic therapy (PDT) and tumor therapy.
JOURNAL OF MATERIALS CHEMISTRY B
(2023)
Article
Chemistry, Multidisciplinary
Caiyan Lai, Bingdong Yan, Run Yuan, Delun Chen, Xiaohong Wang, Mingyu Wang, Heyu He, Jinchun Tu
Summary: In this study, a heterojunction composed of a TiO2 nanosheet and layered Ti3C2 was synthesized. The TiO2/Ti3C2 composites exhibited increased surface area and extended light absorption range, leading to prolonged lifetime of photogenerated carriers. A photoelectrochemical DNA biosensor based on the TiO2/Ti3C2 heterostructure was constructed and comprehensively studied. The sensor displayed stability and sensitivity for DNA detection in the range of 10 nM-10 fM, with a lower detection limit of 6 fM. It provided potential for early diagnosis of various diseases by detecting target DNA.