标题
Applications of targeted proteomics in systems biology and translational medicine
作者
关键词
-
出版物
PROTEOMICS
Volume 15, Issue 18, Pages 3193-3208
出版商
Wiley
发表日期
2015-06-20
DOI
10.1002/pmic.201500004
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Large-Scale Interlaboratory Study to Develop, Analytically Validate and Apply Highly Multiplexed, Quantitative Peptide Assays to Measure Cancer-Relevant Proteins in Plasma
- (2015) Susan E. Abbatiello et al. MOLECULAR & CELLULAR PROTEOMICS
- Extending the Limits of Quantitative Proteome Profiling with Data-Independent Acquisition and Application to Acetaminophen-Treated Three-Dimensional Liver Microtissues
- (2015) Roland Bruderer et al. MOLECULAR & CELLULAR PROTEOMICS
- Large-Scale Targeted Proteomics Using Internal Standard Triggered-Parallel Reaction Monitoring (IS-PRM)
- (2015) Sebastien Gallien et al. MOLECULAR & CELLULAR PROTEOMICS
- Quantitative variability of 342 plasma proteins in a human twin population
- (2015) Y. Liu et al. Molecular Systems Biology
- Screening protein isoforms predictive for cancer using immunoaffinity capture and fast LC-MS in PRM mode
- (2015) Antoine Lesur et al. Proteomics Clinical Applications
- Differential Localization of G Protein βγ Subunits
- (2014) Katherine M. Betke et al. BIOCHEMISTRY
- Multilayered Genetic and Omics Dissection of Mitochondrial Activity in a Mouse Reference Population
- (2014) Yibo Wu et al. CELL
- What Is Wrong with Clinical Proteomics?
- (2014) A. Di Meo et al. CLINICAL CHEMISTRY
- System level dynamics of post-translational modifications
- (2014) Aaron S Gajadhar et al. CURRENT OPINION IN BIOTECHNOLOGY
- Variation and quantification among a target set of phosphopeptides in human plasma by multiple reaction monitoring and SWATH-MS2 data-independent acquisition
- (2014) Anna M. Zawadzka et al. ELECTROPHORESIS
- High-Affinity Recombinant Antibody Fragments (Fabs) Can Be Applied in Peptide Enrichment Immuno-MRM Assays
- (2014) Jeffrey R. Whiteaker et al. JOURNAL OF PROTEOME RESEARCH
- Assessment of Peptide Chemical Modifications on the Development of an Accurate and Precise Multiplex Selected Reaction Monitoring Assay for Apolipoprotein E Isoforms
- (2014) Eduardo Martínez-Morillo et al. JOURNAL OF PROTEOME RESEARCH
- Screening of Missing Proteins in the Human Liver Proteome by Improved MRM-Approach-Based Targeted Proteomics
- (2014) Chen Chen et al. JOURNAL OF PROTEOME RESEARCH
- Anti-Peptide Monoclonal Antibodies Generated for Immuno-Multiple Reaction Monitoring-Mass Spectrometry Assays Have a High Probability of Supporting Western blot and ELISA
- (2014) Regine M. Schoenherr et al. MOLECULAR & CELLULAR PROTEOMICS
- Glycoproteomic Analysis of Prostate Cancer Tissues by SWATH Mass Spectrometry Discovers N-acylethanolamine Acid Amidase and Protein Tyrosine Kinase 7 as Signatures for Tumor Aggressiveness
- (2014) Yansheng Liu et al. MOLECULAR & CELLULAR PROTEOMICS
- Targeted Peptide Measurements in Biology and Medicine: Best Practices for Mass Spectrometry-based Assay Development Using a Fit-for-Purpose Approach
- (2014) Steven A. Carr et al. MOLECULAR & CELLULAR PROTEOMICS
- Antibody-independent targeted quantification of TMPRSS2-ERG fusion protein products in prostate cancer
- (2014) Jintang He et al. Molecular Oncology
- Cell-cycle-regulated activation of Akt kinase by phosphorylation at its carboxyl terminus
- (2014) Pengda Liu et al. NATURE
- Systematic evaluation of quantotypic peptides for targeted analysis of the human kinome
- (2014) Jonathan D Worboys et al. NATURE METHODS
- A sentinel protein assay for simultaneously quantifying cellular processes
- (2014) Martin Soste et al. NATURE METHODS
- Quantitative ADME Proteomics – CYP and UGT Enzymes in the Beagle Dog Liver and Intestine
- (2014) Aki T. Heikkinen et al. PHARMACEUTICAL RESEARCH
- Detection of Mycobacterium tuberculosis Peptides in the Exosomes of Patients with Active and Latent M. tuberculosis Infection Using MRM-MS
- (2014) Nicole A. Kruh-Garcia et al. PLoS One
- An automated, high-throughput method for targeted quantification of intact insulin and its therapeutic analogs in human serum or plasma coupling mass spectrometric immunoassay with high resolution and accurate mass detection (MSIA-HR/AM)
- (2014) Scott Peterman et al. PROTEOMICS
- Glycoproteins identified from heart failure and treatment models
- (2014) Shuang Yang et al. PROTEOMICS
- Targeted Quantitation of Proteins by Mass Spectrometry
- (2013) Daniel C. Liebler et al. BIOCHEMISTRY
- Proteomic analysis of F1F0-ATP synthase super-assembly in mitochondria of cardiomyoblasts undergoing differentiation to the cardiac lineage
- (2013) Elena Bisetto et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Plasma Proteomics, The Human Proteome Project, and Cancer-Associated Alternative Splice Variant Proteins
- (2013) Gilbert S. Omenn BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Encoding and Decoding Cellular Information through Signaling Dynamics
- (2013) Jeremy E. Purvis et al. CELL
- Profiling of Ubiquitin-like Modifications Reveals Features of Mitotic Control
- (2013) Yifat Merbl et al. CELL
- The Mtb Proteome Library: A Resource of Assays to Quantify the Complete Proteome of Mycobacterium tuberculosis
- (2013) Olga T. Schubert et al. Cell Host & Microbe
- Rapid development of sensitive, high-throughput, quantitative and highly selective mass spectrometric targeted immunoassays for clinically important proteins in human plasma and serum
- (2013) Bryan Krastins et al. CLINICAL BIOCHEMISTRY
- Interlaboratory Agreement of Insulin-like Growth Factor 1 Concentrations Measured by Mass Spectrometry
- (2013) H. D. Cox et al. CLINICAL CHEMISTRY
- Measurement of Thyroglobulin by Liquid Chromatography-Tandem Mass Spectrometry in Serum and Plasma in the Presence of Antithyroglobulin Autoantibodies
- (2013) M. M. Kushnir et al. CLINICAL CHEMISTRY
- Analysis of protein expression in zebrafish during gonad differentiation by targeted proteomics
- (2013) Ksenia J. Groh et al. GENERAL AND COMPARATIVE ENDOCRINOLOGY
- A Highly Sensitive Targeted Mass Spectrometric Assay for Quantification of AGR2 Protein in Human Urine and Serum
- (2013) Tujin Shi et al. JOURNAL OF PROTEOME RESEARCH
- Quantification of ErbB Network Proteins in Three Cell Types Using Complementary Approaches Identifies Cell-General and Cell-Type-Specific Signaling Proteins
- (2013) Christina Kiel et al. JOURNAL OF PROTEOME RESEARCH
- Targeted Quantitative Proteomics for the Analysis of 14 UGT1As and -2Bs in Human Liver Using NanoUPLC–MS/MS with Selected Reaction Monitoring
- (2013) John K. Fallon et al. JOURNAL OF PROTEOME RESEARCH
- Diabetic nephropathy induces changes in the proteome of human urinary exosomes as revealed by label-free comparative analysis
- (2013) Irene Zubiri et al. Journal of Proteomics
- SAINTexpress: Improvements and additional features in Significance Analysis of INTeractome software
- (2013) Guoci Teo et al. Journal of Proteomics
- N-Glycoprotein SRMAtlas
- (2013) Ruth Hüttenhain et al. MOLECULAR & CELLULAR PROTEOMICS
- The Utility of Paradoxical Components in Biological Circuits
- (2013) Yuval Hart et al. MOLECULAR CELL
- Targeted proteomics reveals strain-specific changes in the mouse insulin and central metabolic pathways after a sustained high-fat diet
- (2013) E. Sabido et al. Molecular Systems Biology
- Cell type-specific nuclear pores: a case in point for context-dependent stoichiometry of molecular machines
- (2013) A. Ori et al. Molecular Systems Biology
- A complete mass-spectrometric map of the yeast proteome applied to quantitative trait analysis
- (2013) Paola Picotti et al. NATURE
- Demonstrating the feasibility of large-scale development of standardized assays to quantify human proteins
- (2013) Jacob J Kennedy et al. NATURE METHODS
- Lysine 63-linked polyubiquitination is required for EGF receptor degradation
- (2013) F. Huang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Connecting Genomic Alterations to Cancer Biology with Proteomics: The NCI Clinical Proteomic Tumor Analysis Consortium
- (2013) M. J. Ellis et al. Cancer Discovery
- Perturbation Biology: Inferring Signaling Networks in Cellular Systems
- (2013) Evan J. Molinelli et al. PLoS Computational Biology
- Sequential Protein and Peptide Immunoaffinity Capture for Mass Spectrometry-Based Quantification of Total Human β-Nerve Growth Factor
- (2012) Hendrik Neubert et al. ANALYTICAL CHEMISTRY
- Mass Spectrometry–Based Proteomics and Network Biology
- (2012) Ariel Bensimon et al. Annual Review of Biochemistry
- Connexin multi-site phosphorylation: Mass spectrometry-based proteomics fills the gap
- (2012) Vincent C. Chen et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Expanding applications of chemical genetics in signal transduction
- (2012) Scott M. Carlson et al. CELL CYCLE
- Biomarker Failures
- (2012) J. P. A. Ioannidis CLINICAL CHEMISTRY
- Novel prognostic protein markers of resectable pancreatic cancer identified by coupled shotgun and targeted proteomics using formalin-fixed paraffin-embedded tissues
- (2012) Tatsuyuki Takadate et al. INTERNATIONAL JOURNAL OF CANCER
- Precision of Multiple Reaction Monitoring Mass Spectrometry Analysis of Formalin-Fixed, Paraffin-Embedded Tissue
- (2012) Robert W. Sprung et al. JOURNAL OF PROTEOME RESEARCH
- Multiplex Targeted Proteomic Assay for Biomarker Detection in Plasma: A Pancreatic Cancer Biomarker Case Study
- (2012) Sheng Pan et al. JOURNAL OF PROTEOME RESEARCH
- Comparative and Targeted Proteomic Analyses of Urinary Microparticles from Bladder Cancer and Hernia Patients
- (2012) Chien-Lun Chen et al. JOURNAL OF PROTEOME RESEARCH
- Targeted Data Extraction of the MS/MS Spectra Generated by Data-independent Acquisition: A New Concept for Consistent and Accurate Proteome Analysis
- (2012) Ludovic C. Gillet et al. MOLECULAR & CELLULAR PROTEOMICS
- Differential network biology
- (2012) Trey Ideker et al. Molecular Systems Biology
- Selected reaction monitoring–based proteomics: workflows, potential, pitfalls and future directions
- (2012) Paola Picotti et al. NATURE METHODS
- Quantitative analysis of peptides and proteins in biomedicine by targeted mass spectrometry
- (2012) Michael A Gillette et al. NATURE METHODS
- Dynamic Proteomics of Human Protein Level and Localization across the Cell Cycle
- (2012) Shlomit Farkash-Amar et al. PLoS One
- Antibody-free, targeted mass-spectrometric approach for quantification of proteins at low picogram per milliliter levels in human plasma/serum
- (2012) T. Shi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Range of protein detection by selected/multiple reaction monitoring mass spectrometry in an unfractionated human cell culture lysate
- (2012) H. Alexander Ebhardt et al. PROTEOMICS
- MRM-based multiplexed quantitation of 67 putative cardiovascular disease biomarkers in human plasma
- (2012) Dominik Domanski et al. PROTEOMICS
- PASSEL: The PeptideAtlas SRMexperiment library
- (2012) Terry Farrah et al. PROTEOMICS
- Reproducible Quantification of Cancer-Associated Proteins in Body Fluids Using Targeted Proteomics
- (2012) R. Huttenhain et al. Science Translational Medicine
- Post-translational modification: nature's escape from genetic imprisonment and the basis for dynamic information encoding
- (2012) Sudhakaran Prabakaran et al. Wiley Interdisciplinary Reviews-Systems Biology and Medicine
- Interactome Networks and Human Disease
- (2011) Marc Vidal et al. CELL
- Novel Prognostic Markers in the Serum of Patients With Castration-Resistant Prostate Cancer Derived From Quantitative Analysis of the Pten Conditional Knockout Mouse Proteome
- (2011) Martin Kälin et al. EUROPEAN UROLOGY
- In-Depth Proteomics of Ovarian Cancer Ascites: Combining Shotgun Proteomics and Selected Reaction Monitoring Mass Spectrometry
- (2011) Sarah Elschenbroich et al. JOURNAL OF PROTEOME RESEARCH
- Rapid Verification of Candidate Serological Biomarkers Using Gel-based, Label-free Multiple Reaction Monitoring
- (2011) Hsin-Yao Tang et al. JOURNAL OF PROTEOME RESEARCH
- ELISA and Multiplex Technologies for Cytokine Measurement in Inflammation and Aging Research
- (2011) S. X. Leng et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Accurate Quantification of Cardiovascular Biomarkers in Serum Using Protein Standard Absolute Quantification (PSAQ™) and Selected Reaction Monitoring
- (2011) Céline Huillet et al. MOLECULAR & CELLULAR PROTEOMICS
- Interlaboratory Evaluation of Automated, Multiplexed Peptide Immunoaffinity Enrichment Coupled to Multiple Reaction Monitoring Mass Spectrometry for Quantifying Proteins in Plasma
- (2011) Eric Kuhn et al. MOLECULAR & CELLULAR PROTEOMICS
- Monitoring a Nuclear Factor-κB Signature of Drug Resistance in Multiple Myeloma
- (2011) Yun Xiang et al. MOLECULAR & CELLULAR PROTEOMICS
- Stimulus-dependent dynamics of p53 in single cells
- (2011) E. Batchelor et al. Molecular Systems Biology
- A pipeline that integrates the discovery and verification of plasma protein biomarkers reveals candidate markers for cardiovascular disease
- (2011) Terri A Addona et al. NATURE BIOTECHNOLOGY
- Selected reaction monitoring mass spectrometry reveals the dynamics of signaling through the GRB2 adaptor
- (2011) Nicolas Bisson et al. NATURE BIOTECHNOLOGY
- A targeted proteomics–based pipeline for verification of biomarkers in plasma
- (2011) Jeffrey R Whiteaker et al. NATURE BIOTECHNOLOGY
- Rapid empirical discovery of optimal peptides for targeted proteomics
- (2011) Andrew B Stergachis et al. NATURE METHODS
- Protein 3D Structure Computed from Evolutionary Sequence Variation
- (2011) Debora S. Marks et al. PLoS One
- Mutant proteins as cancer-specific biomarkers
- (2011) Q. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cancer genetics-guided discovery of serum biomarker signatures for diagnosis and prognosis of prostate cancer
- (2011) I. Cima et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Systematic quantification of peptides/proteins in urine using selected reaction monitoring
- (2011) Nathalie Selevsek et al. PROTEOMICS
- Abacus: A computational tool for extracting and pre-processing spectral count data for label-free quantitative proteomic analysis
- (2011) Damian Fermin et al. PROTEOMICS
- A database of reaction monitoring mass spectrometry assays for elucidating therapeutic response in cancer
- (2011) Elizabeth R. Remily-Wood et al. Proteomics Clinical Applications
- Targeted label-free quantitative analysis of secretory proteins from adipocytes in response to oxidative stress
- (2010) Sunkyu Choi et al. ANALYTICAL BIOCHEMISTRY
- Determination of Protein Stoichiometry within Protein Complexes Using Absolute Quantification and Multiple Reaction Monitoring
- (2010) Carla Schmidt et al. ANALYTICAL CHEMISTRY
- Enzyme Promiscuity: A Mechanistic and Evolutionary Perspective
- (2010) Olga Khersonsky and Dan S. Tawfik Annual Review of Biochemistry
- A Decade of Systems Biology
- (2010) Han-Yu Chuang et al. Annual Review of Cell and Developmental Biology
- Microparticles
- (2010) Sebastian F. Mause et al. CIRCULATION RESEARCH
- Online High-Flow Peptide Immunoaffinity Enrichment and Nanoflow LC-MS/MS: Assay Development for Total Salivary Pepsin/Pepsinogen
- (2010) H. Neubert et al. CLINICAL CHEMISTRY
- A Modified “Cross-talk” between Histone H2B Lys-120 Ubiquitination and H3 Lys-79 Methylation
- (2010) Agus Darwanto et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Combination of Improved18O Incorporation and Multiple Reaction Monitoring: A Universal Strategy for Absolute Quantitative Verification of Serum Candidate Biomarkers of Liver Cancer
- (2010) Yan Zhao et al. JOURNAL OF PROTEOME RESEARCH
- Quantification of β-Catenin Signaling Components in Colon Cancer Cell Lines, Tissue Sections, and Microdissected Tumor Cells using Reaction Monitoring Mass Spectrometry
- (2010) Yi Chen et al. JOURNAL OF PROTEOME RESEARCH
- Targeted Quantitation of Site-Specific Cysteine Oxidation in Endogenous Proteins Using a Differential Alkylation and Multiple Reaction Monitoring Mass Spectrometry Approach
- (2010) Jason M. Held et al. MOLECULAR & CELLULAR PROTEOMICS
- Mass spectrometry in high-throughput proteomics: ready for the big time
- (2010) Tommy Nilsson et al. NATURE METHODS
- Preferentially Increased Nitration of α-Synuclein at Tyrosine-39 in a Cellular Oxidative Model of Parkinson’s Disease
- (2009) Steven R. Danielson et al. ANALYTICAL CHEMISTRY
- Full Dynamic Range Proteome Analysis of S. cerevisiae by Targeted Proteomics
- (2009) Paola Picotti et al. CELL
- Quantitative Analysis of an Aberrant Glycoform of TIMP1 from Colon Cancer Serum by L-PHA-Enrichment and SISCAPA with MRM Mass Spectrometry
- (2009) Yeong Hee Ahn et al. JOURNAL OF PROTEOME RESEARCH
- Multiple Reaction Monitoring-based, Multiplexed, Absolute Quantitation of 45 Proteins in Human Plasma
- (2009) Michael A. Kuzyk et al. MOLECULAR & CELLULAR PROTEOMICS
- Quantification of Cardiovascular Biomarkers in Patient Plasma by Targeted Mass Spectrometry and Stable Isotope Dilution
- (2009) Hasmik Keshishian et al. MOLECULAR & CELLULAR PROTEOMICS
- Multi-site assessment of the precision and reproducibility of multiple reaction monitoring–based measurements of proteins in plasma
- (2009) Terri A Addona et al. NATURE BIOTECHNOLOGY
- Targeted proteomics using selected reaction monitoring reveals the induction of specific terpene synthases in a multi-level study of methyl jasmonate-treated Norway spruce (Picea abies)
- (2009) Katherine G. Zulak et al. PLANT JOURNAL
- Quantification of Thyroglobulin, a Low-Abundance Serum Protein, by Immunoaffinity Peptide Enrichment and Tandem Mass Spectrometry
- (2008) A. N. Hoofnagle et al. CLINICAL CHEMISTRY
- Multiple Reaction Monitoring of mTRAQ-Labeled Peptides Enables Absolute Quantification of Endogenous Levels of a Potential Cancer Marker in Cancerous and Normal Endometrial Tissues
- (2008) Leroi V. DeSouza et al. JOURNAL OF PROTEOME RESEARCH
- Use of an Immunoaffinity-Mass Spectrometry-based Approach for the Quantification of Protein Biomarkers from Serum Samples of Lung Cancer Patients
- (2008) Gordon R. Nicol et al. MOLECULAR & CELLULAR PROTEOMICS
- Targeted Quantitative Analysis ofStreptococcus pyogenesVirulence Factors by Multiple Reaction Monitoring
- (2008) Vinzenz Lange et al. MOLECULAR & CELLULAR PROTEOMICS
- Clinical Quantitation of Prostate-specific Antigen Biomarker in the Low Nanogram/Milliliter Range by Conventional Bore Liquid Chromatography-Tandem Mass Spectrometry (Multiple Reaction Monitoring) Coupling and Correlation with ELISA Tests
- (2008) Tanguy Fortin et al. MOLECULAR & CELLULAR PROTEOMICS
- Protein Standard Absolute Quantification (PSAQ) for improved investigation of staphylococcal food poisoning outbreaks
- (2008) Alain Dupuis et al. PROTEOMICS
- The interface between biomarker discovery and clinical validation: The tar pit of the protein biomarker pipeline
- (2008) Amanda G. Paulovich et al. Proteomics Clinical Applications
- Why Are Computational Neuroscience and Systems Biology So Separate?
- (2008) Erik De Schutter PLoS Computational Biology
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started