Article
Clinical Neurology
Hadar Fisher, Nili Solomonov, Fredrik Falkenstrom, Ben Shahar, Simon Shamay-Tsoory, Sigal Zilcha-Mano
Summary: Existing literature suggests that patients' experiences of negative emotions predict outcomes in psychotherapies for major depressive disorder. This study investigates the potential mediation effect of therapists' oxytocin (OT) responses on the association between patients' negative emotions and symptomatic change. The findings support a within-person mediation model where higher levels of negative emotions in patients predict greater increases in therapist OT levels pre- to post-session, and therapist OT levels, in turn, predict reduction in patients' depressive symptoms.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Nutrition & Dietetics
Madeline Keyes, Chloe Andrews, Vishal Midya, Paula Carrasco, Monica Guxens, Alba Jimeno-Romero, Mario Murcia, Cristina Rodriguez-Dehli, Dora Romaguera, Loreto Santa-Maria, Marina Vafeiadi, Lida Chatzi, Emily Oken, Martine Vrijheid, Damaskini Valvi, Sarbattama Sen
Summary: This study found that maternal obesity before pregnancy is associated with shorter duration of breastfeeding, and potential mediators of this association include birthweight, maternal C-reactive protein levels during pregnancy, cesarean delivery, maternal dietary inflammatory index, gestational age at delivery, and gestational diabetes mellitus. These findings provide potential targets for interventions to improve breastfeeding outcomes.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2023)
Review
Obstetrics & Gynecology
Sarah Buckley, Kerstin Uvnas-Moberg, Zada Pajalic, Karolina Luegmair, Anette Ekstrom-Bergstrom, Anna Dencker, Claudia Massarotti, Alicja Kotlowska, Leonie Callaway, Sandra Morano, Ibone Olza, Claudia Meier Magistretti
Summary: Synthetic oxytocin increases maternal plasma oxytocin levels during labor, but does not affect newborn oxytocin levels. However, its use during labor can change uterine contraction patterns, potentially harming the fetus and increasing maternal pain and stress.
BMC PREGNANCY AND CHILDBIRTH
(2023)
Article
Environmental Sciences
Zixia Wang, Rong Shi, Guodong Ding, Qian Yao, Chengyu Pan, Yu Gao, Ying Tian
Summary: This study found that prenatal exposure to PFASs was associated with an increased risk of diarrhea in infants, especially among those who were exclusively breastfed, but not with common cold or bronchitis/pneumonia.
Article
Nursing
Barbara Figueiredo, Tiago Miguel Pinto, Raquel Costa
Summary: The study found that exclusive breastfeeding at 3 months moderates the association between prenatal and postpartum depression. Participants with prenatal depression who were exclusively breastfeeding at 3 months showed fewer symptoms of depression and lower rates of depression between 3 and 6 months postpartum. On the other hand, participants without prenatal depression who were exclusively breastfeeding at 3 months showed similar depression symptoms and rates of depression compared to those who were not exclusively breastfeeding.
JOURNAL OF HUMAN LACTATION
(2021)
Article
Endocrinology & Metabolism
Jani Kajanoja, Saara Nolvi, Katri Kantojarvi, Linnea Karlsson, Tiina Paunio, Hasse Karlsson
Summary: Maternal prenatal stress may have long-term adverse consequences for child development. The oxytocin-receptor genotype may moderate the association between maternal stress during pregnancy and child social-emotional development. Infants with risk genotypes are more susceptible to the negative effects of maternal prenatal anxiety, while those with fewer or no risk genotypes are less affected.
PSYCHONEUROENDOCRINOLOGY
(2022)
Article
Health Care Sciences & Services
Esmeralda Santacruz-Salas, Antonio Segura-Fragoso, Diana P. Pozuelo-Carrascosa, Ana Isabel Cobo-Cuenca, Juan Manuel Carmona-Torres, Jose Alberto Laredo-Aguilera
Summary: The study found that the prevalence of EBF at 6 months was 19.49%, with factors influencing EBF maintenance including prior decision to practice EBF, belief in the sufficiency of EBF, not offering water or fluid to the child, delaying pacifier use, longer gestation time, and previous experience with EBF for more than 6 months. The earliest reason for EBF cessation was the mother's lack of self-efficacy. Understanding these factors is crucial for helping mothers and preventing early weaning.
JOURNAL OF PERSONALIZED MEDICINE
(2021)
Article
Nutrition & Dietetics
Emily Zimmerman, Kennedy K. Gachigi, Rachel F. Rodgers, Deborah J. Watkins, Megan Woodbury, Jose F. Cordero, Akram Alshawabkeh, John D. Meeker, Gredia Huerta-Montanez, Zaira Rosario Pabon, Morgan Hines, Carmen M. Velez-Vega, Carlos A. Camargo, Yeyi Zhu, Sara S. Nozadi, Sarah S. Comstock, Christine Hockett, Patrick M. Tarwater
Summary: This study examines the relationship between maternal food source and preparation during pregnancy and the duration of breastfeeding. The findings suggest that mothers with high food source quality breastfeed for a longer duration compared to those with moderate and low food source quality.
Article
Nursing
Ana Paola Campos, Summer Sherburne Hawkins
Summary: Research in Mexico shows that maternal employment status and household income can influence the duration of breastfeeding. In lower-income households, mothers who work part-time informally are less likely to breastfeed for 6 months or more. In higher-income households, mothers who work full-time formally are also less likely to breastfeed for the same duration. Measures are needed to support mothers and develop strategies to promote breastfeeding.
JOURNAL OF HUMAN LACTATION
(2022)
Article
Neurosciences
Yuki Takahashi, Kerstin Uvnas-Moberg, Eva Nissen, Lena Lidfors, Anna-Berit Ransjo-Arvidson, Wibke Jonas
Summary: The study found that mothers who received epidural analgesia negatively influenced infant rooting behavior and maternal mean oxytocin levels, while oxytocin infusion alone had no effect. Infants who suck well stimulate oxytocin release more efficiently, leading to a better stimulation of milk production and consequently to a reduced infant weight loss 2 days after birth.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Pediatrics
Qin-Qin Gong, Dan-Dan Quan, Chong Guo, Chao Zhang, Zhi-Jun Zhang
Summary: Breastfeeding has a potential protective role in preventing selective childhood cancer growth, especially for acute lymphocytic leukemia, acute myeloid leukemia, and cancers of the nervous and urinary systems. Prolonging the duration of breastfeeding is recommended to prevent the development of selective childhood cancer.
ITALIAN JOURNAL OF PEDIATRICS
(2022)
Article
Clinical Neurology
Kate Lindley Baron-Cohen, Ruth Feldman, Pasco Fearon, Peter Fonagy
Summary: This study found individual differences in response to oxytocin treatment and suggested that it may offer treatment benefits to new mothers reporting moderate subclinical levels of depression.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Environmental Sciences
Tai-Ho Hung, Te-Yao Hsu, Tao-Hsin Tung, Ching-Chang Tsai, Chia-Yu Ou, Fen-Fang Chung, Gwo-Hwa Wan
Summary: This study found that exposure to air pollutants during different stages of pregnancy can directly affect fetal birth weight, including PM10, PM2.5, O3, and SO2. Changes in TNF-? concentrations in maternal blood mediate the effects on fetal weight, suggesting that exposure to air pollutants may have both direct and indirect effects on reducing fetal weight.
ENVIRONMENTAL RESEARCH
(2021)
Review
Clinical Neurology
Mengjie Xia, Jing Luo, Junqiang Wang, Yong Liang
Summary: There is an association between breastfeeding and postpartum depression, with breastfeeding being associated with a lower risk of postpartum depression. The duration of breastfeeding and exclusive breastfeeding have different effects on the risk of postpartum depression.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Nutrition & Dietetics
Wei Wei Pang, Donna T. Geddes, Ching-Tat Lai, Shiao-Yng Chan, Yiong Huak Chan, Clara Y. Cheong, Doris Fok, Mei Chien Chua, Sok Bee Lim, Jonathan Huang, Shikha Pundir, Kok Hian Tan, Fabian Yap, Keith M. Godfrey, Peter D. Gluckman, Lynette P. Shek, Mark H. Vickers, Johan G. Eriksson, Yap-Seng Chong, Mary E. Wlodek
Summary: Maternal gestational hyperglycemia may be associated with a shorter duration of breastfeeding, particularly for those with fasting plasma glucose (FPG) levels of 5.1 mmol/L or higher. However, there does not appear to be a significant impact on other components of breastmilk. Further research is needed to determine whether milk production plays a role in predicting breastfeeding duration among women with elevated FPG during pregnancy.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2021)
Meeting Abstract
Obstetrics & Gynecology
Alison M. Stuebe, Samantha Meltzer-Brody, Brenda Pearson, Cheryl Walker, Karen Grewen
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2018)
Article
Psychiatry
Anna E. Bauer, Merete L. Maegbaek, Xiaoqin Liu, Naomi R. Wray, Patrick F. Sullivan, William C. Miller, Samantha Meltzer-Brody, Trine Munk-Olsen
AMERICAN JOURNAL OF PSYCHIATRY
(2018)
Article
Psychiatry
Christine Pao, Jerry Guintivano, Hudson Santos, Samantha Meltzer-Brody
ARCHIVES OF WOMENS MENTAL HEALTH
(2019)
Meeting Abstract
Neurosciences
Jerry Guintivano, Holly Krohn, Carol Lewis, Alexander Ploner, Patrick Sullivan, Samantha Meltzer-Brody
BIOLOGICAL PSYCHIATRY
(2018)
Meeting Abstract
Neurosciences
Samantha Meltzer-Brody, Stephen Kanes, Robert Riesenberg, C. Neill Epperson, Kristina Deligiannidis, David Rubinow, Haihong Li, Christine Clemson, Helen Colquhoun
BIOLOGICAL PSYCHIATRY
(2018)
Review
Obstetrics & Gynecology
Jerry Guintivano, Tracy Manuck, Samantha Meltzer-Brody
CLINICAL OBSTETRICS AND GYNECOLOGY
(2018)
Article
Medicine, General & Internal
Margaret E. Gerbasi, Mark Kosinski, Samantha Meltzer-Brody, Sarah Acaster, Moshe Fridman, Ming-Yi Huang, Vijayveer Bonthapally, Paul Hodgkins, Stephen J. Kanes, Adi Eldar-Lissai
Summary: Postpartum depression significantly impacts the health-related quality of life (HRQoL) of patients, but achieving rapid clinical response (day 7) and sustained response after treatment (day 30) can lead to substantial improvements in HRQoL. Therefore, early identification of women with postpartum depression and providing effective treatment options is crucial.
CURRENT MEDICAL RESEARCH AND OPINION
(2021)
Article
Psychology, Clinical
Yasmin V. Barrios, Joanna Maselko, Stephanie M. Engel, Brian W. Pence, Andrew F. Olshan, Samantha Meltzer-Brody, Nancy Dole, John M. Thorp
Summary: This study revealed that high psychosocial adversity was associated with persistent and comorbid depressive symptoms and anxiety during pregnancy. Assessing psychosocial adversity can help identify pregnant women at increased risk who would benefit from tailored mental health interventions.
DEPRESSION AND ANXIETY
(2021)
Article
Psychology, Clinical
Jacqueline Kiewa, Samantha Meltzer-Brody, Jeanette Milgrom, Jerry Guintivano, Ian B. Hickie, David C. Whiteman, Catherine M. Olsen, Lucia Colodro-Conde, Sarah E. Medland, Nicholas G. Martin, Naomi R. Wray, Enda M. Byrne
Summary: The study found a high genetic overlap between perinatal depression (PND) and major depressive disorder (MDD), with main distinctions in genes differentially expressed in ovarian tissue and higher MDD polygenic score (PGS), particularly for women experiencing both antenatal and postpartum PND.
DEPRESSION AND ANXIETY
(2022)
Article
Psychiatry
Anna E. Bauer, Jerry Guintivano, Holly Krohn, Patrick F. Sullivan, Samantha Meltzer-Brody
Summary: The COVID-19 pandemic has significantly affected mothers with a history of peripartum depression, leading to high levels of perceived stress and strong associations with depressive and anxious symptoms. Perceived stress is the strongest predictor, and feelings of lack of control and hopelessness increase symptoms. The collective trauma of the pandemic has long-term and dynamic effects on the mental health of mothers, emphasizing the need for flexible and responsive interventions that address fear, trauma, and feelings of control.
ARCHIVES OF WOMENS MENTAL HEALTH
(2022)
Article
Psychiatry
Joanna Collaton, Cindy-Lee Dennis, Valerie H. Taylor, Sophie Grigoriadis, Tim F. Oberlander, Benicio N. Frey, Ryan Van Lieshout, Jerry Guintivano, Samantha Meltzer-Brody, James L. Kennedy, Simone N. Vigod
Summary: This study evaluated the feasibility of enrolling Canadian women with postpartum depression and postpartum psychosis using a mobile application for an international psychiatric genetics study and identified clinically distinct subtypes of postpartum depression based on participant responses.
Article
Health Care Sciences & Services
Holly Krohn, Jerry Guintivano, Rachel Frische, Jamie Steed, Hannah Rackers, Samantha Meltzer-Brody
Summary: This study investigated the clinical utility, predictive ability, and acceptability of using ecological momentary assessment to collect daily mood, sleep, and activity data through the use of an Apple Watch and mobile app among women with postpartum depression. The results showed that this tracking method was largely endorsed as acceptable and clinically useful, providing an innovative solution to increase care access during the COVID-19 pandemic.
JMIR FORMATIVE RESEARCH
(2022)
Article
Criminology & Penology
Candace Killian-Farrell, Cynthia F. Rizo, Brianna M. Lombardi, Samantha Meltzer-Brody, Sarah E. Bledsoe
JOURNAL OF INTERPERSONAL VIOLENCE
(2020)
Article
Psychology, Clinical
S. Meltzer-Brody, J. T. Larsen, L. Petersen, J. Guintivano, A. Di Florio, W. C. Miller, P. F. Sullivan, T. Munk-Olsen
DEPRESSION AND ANXIETY
(2018)
Article
Psychiatry
Trine Munk-Olsen, Xiaoqin Liu, Alexander Viktorin, Hilary K. Brown, Arianna Di Florio, Brian M. D'Onofrio, Tara Gomes, Louise M. Howard, Hind Khalifeh, Holly Krohn, Henrik Larsson, Paul Lichtenstein, Clare L. Taylor, Inge Van Kamp, Richard Wesseloo, Samantha Meltzer-Brody, Simone N. Vigod, Veerle Bergink