Article
Microbiology
Ana Carolina Ewbank, Danny Fuentes-Castillo, Carlos Sacristan, Fernanda Esposito, Bruna Fuga, Brenda Cardoso, Silvia Neri Godoy, Roberta Ramblas Zamana, Marco Aurelio Gattamorta, Jose Luiz Catao-Dias, Nilton Lincopan
Summary: This study investigated wild magnificent frigatebirds in the Alcatrazes Archipelago in Brazil and found highly virulent multidrug-resistant Escherichia coli strains in these birds. These strains carried both extended-spectrum-beta-lactamase (ESBL) and plasmid-encoded AmpC (pAmpC), indicating their resistance to multiple antimicrobial agents. The presence of these antibiotic-resistant bacteria suggests potential zoonotic transmission and highlights the importance of monitoring wildlife for pathogens of critical priority.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Marine & Freshwater Biology
Fabio Schunck, Fabio Toledo das Dores, Natalia Dantas Paes, Marcos Antonio Melo, Bianca Matinata, Marcelo Bokermann, Ingo Grantsau
Summary: The Magnificent Frigatebird Fregata magnificens has a large nesting colony in Southeast Brazil, but there is a lack of studies on its occurrence in other areas. This study evaluated the occurrence of the bird in the Metropolitan Region of Sao Paulo, and found 31 records dating back to 1960. The occurrence is attributed to the proximity to the coast and the high flight capacity of the birds.
MARINE ORNITHOLOGY
(2023)
Article
Veterinary Sciences
Ana C. Ewbank, Aricia Duarte-Benvenuto, Roberta Zamana Ramblas, Marco A. Gattamorta, Silvia Neri Godoy, Mara L. Gravinatti, Paulo E. Brandao, Jose Prime L. Catao-Dias, Carlos Sacristan
Summary: We investigated the presence of herpesvirus, flavivirus, and coronavirus in 20 Magnificent Frigatebirds from Alcatrazes Island, Brazil. One bird tested positive for herpesvirus, while no samples were positive for flavivirus or coronavirus. The detected herpesvirus was similar to the one causing mortality in Frigatebird chicks in French Guiana. The Alcatrazes archipelago is home to a large frigatebird breeding colony, and further studies are needed to understand the epidemiologic relevance of these viruses in seabirds.
JOURNAL OF WILDLIFE DISEASES
(2023)
Review
Biochemistry & Molecular Biology
Clare Burn Aschner, Betsy C. Herold
Summary: Vaccines for alphaherpesviruses like VZV and HSV types 1 and 2 have shown varying levels of success, with live viral vaccines for chickenpox and subunit therapeutic vaccines for zoster proving highly successful. However, efforts to develop effective vaccines against HSV-1 and HSV-2 have been met with limited success. Different vaccine modalities elicit different types of immune responses, highlighting the need to reconsider preclinical models and immune correlates of protection against HSV.
CURRENT ISSUES IN MOLECULAR BIOLOGY
(2021)
Article
Veterinary Sciences
D. W. Goldberg, R. E. T. Vanstreels, M. M. Alcala, R. Hurtado, P. F. Mantovani, L. S. T. Cunha, P. P. Serafini, A. F. Barbosa
Summary: Kite string injuries have a significant impact on magnificent frigatebirds, with most individuals unable to fully recover and be released back into the wild. An atypical increase in kite string injuries was observed during the pandemic, indicating how such events may exacerbate human-wildlife conflicts.
Article
Agriculture, Dairy & Animal Science
Bin Song, Teng Ma, Damien P. Preveraud, Keying Zhang, Jianping Wang, Xuemei Ding, Qiufeng Zeng, Huanwei Peng, Jie Bai, Li Lv, Yue Xuan, Shiping Bai
Summary: Feeding myco-toxin-contaminated corn reduces hatchability and increases embryo mortality in breeder hens, as well as negatively affects the growth of their progeny chicks. The addition of mycotoxin sequestrant alleviates these toxic effects.
Article
Immunology
Alessandra Martucciello, Anna Balestrieri, Cecilia Righi, Giovanna Cappelli, Eleonora Scoccia, Carlo Grassi, Sergio Brandi, Elisabetta Rossi, Giorgio Galiero, Damiano Gioia, Giovanna Fusco, Francesco Feliziani, Esterina De Carlo, Stefano Petrini
Summary: The European regulations on infectious disease control provide measures to control BoHV-1 infection in cattle and buffalo. Due to the serological cross-reactivity between BoHV-1 and BuHV-1, a new immunization protocol using BoHV-1 gE-deleted marker vaccines was tested in water buffaloes. However, the findings did not support the protective role of this protocol against wild-type BuHV-1.
Review
Veterinary Sciences
Tong Zhou, Mingshu Wang, Anchun Cheng, Qiao Yang, Bin Tian, Ying Wu, Renyong Jia, Shun Chen, Mafeng Liu, Xin-Xin Zhao, Xuming Ou, Sai Mao, Di Sun, Shaqiu Zhang, Dekang Zhu, Juan Huang, Qun Gao, Yanling Yu, Ling Zhang
Summary: This article mainly describes the viral protein kinases and their mechanisms of regulating viral protein function through phosphorylation. The study of post-translational modification of viral proteins is of great significance for understanding viral infection mechanisms and developing antiviral treatment.
VETERINARY RESEARCH
(2022)
Review
Biochemistry & Molecular Biology
Chad Kuny, Moriah L. Szpara
Summary: Alphaherpesviruses, previously thought to be genetically stable, are now known to exist as diverse populations. Recent advances in high-throughput sequencing and bioinformatics have expanded our understanding of their genomes. Insights from related veterinary species and other subfamilies of herpesviruses have provided valuable information for future research in herpesvirus genomics.
CURRENT ISSUES IN MOLECULAR BIOLOGY
(2021)
Article
Multidisciplinary Sciences
Ke Xiao, Dan Xiong, Gong Chen, Jinsong Yu, Yue Li, Kening Chen, Lu Zhang, Yangyang Xu, Qian Xu, Xi Huang, Anran Gao, Kai Cao, Keji Yan, Jinxia Dai, Xueying Hu, Yijun Ruan, Zhenfang Fu, Guoliang Li, Gang Cao
Summary: This study demonstrates a genome-wide trans-species chromatin interaction between pseudorabies virus (PRV) and host cells, where the viral genome is delivered into the open and active chromatin zone by the host DNA binding protein RUNX1. This facilitates viral gene transcription by hijacking host transcription machinery, a process significantly inhibited by either a RUNX1 inhibitor or RNA interference. These findings provide insights into herpesvirus genome transcription and suggest new research directions in this area.
Article
Cell Biology
Robert J. J. Jansens, Ruth Verhamme, Aashiq H. Mirza, Anthony Olarerin-George, Cliff Van Waesberghe, Samie R. Jaffrey, Herman W. Favoreel
Summary: Chemical modifications of mRNA, such as N6-methyladenosine (m6A), play a role in post-transcriptional gene regulation. This study found that alphaherpesvirus kinases can trigger phosphorylation of components of the m6A methyltransferase complex, leading to its inhibition and a decrease in m6A levels in virus-infected cells. The viral US3 protein is responsible for this phosphorylation and inhibition, and while inactivation of the m6A methyltransferase complex is not necessary for virus replication, the m6A methylation motif is underrepresented in alphaherpesvirus genomes.
Article
Virology
Claudia Cerracchio, Maria Grazia Amoroso, Marialuisa Piccolo, Maria Grazia Ferraro, Francesca Paola Nocera, Luisa De Martino, Francesco Serra, Carlo Irace, Gian Carlo Tenore, Ettore Novellino, Rita Santamaria, Filomena Fiorito
Summary: The study found that Taurisolo (R) may serve as a potential antiviral agent against BoAHV-1 infection. It enhances cell viability and reduces virus production in infected cells. The up-regulation of AhR may be involved in these effects and could become a new target for antiviral therapy.
Article
Virology
Abdul Rahman Siregar, Sabine Gartner, Jasper Gotting, Philipp Stegen, Artur Kaul, Thomas F. Schulz, Stefan Pohlmann, Michael Winkler
Summary: This study reports the development of a recombinant system for PaHV2 and the generation of viruses carrying reporter genes. These viruses can be used to analyze the susceptibility of cells to infection and the inhibitory effects of neutralizing antibodies and antiviral compounds.
Article
Multidisciplinary Sciences
Guennur Pesmen
Summary: This study discusses the relationship between chick length and egg weight, live weight, and chick quality in domestic geese. The results show a positive and significant relationship between chick length and these factors. It is suggested that chick length could be used as an indicator for evaluating chick quality.
JOURNAL OF RADIATION RESEARCH AND APPLIED SCIENCES
(2023)
Article
Virology
Dora Tombacz, Balazs Kakuk, Gabor Torma, Zsolt Csabai, Gabor Gulyas, Vivien Tamas, Zoltan Zadori, Victoria A. Jefferson, Florencia Meyer, Zsolt Boldogkoi
Summary: This study utilized a long-read sequencing technique based on the Oxford Nanopore Technology MinION platform to characterize the transcriptome of bovine alphaherpesvirus type 1 (BoHV-1) over a 12-hour infection period. The research revealed the presence of multiple transcription start sites from a single promoter, with different distribution patterns across viral genes but similar patterns within the same gene at different timepoints. It was also discovered that the circ gene expressed with immediate-early (IE) kinetics by utilizing the promoter of another IE gene (bicp4) for transcriptional control. Additionally, an overlap between DNA replication initiation and transcription from the bicp22 gene was detected, suggesting an interaction between the two molecular processes.
Article
Microbiology
Gonzalo Bello, Ighor Arantes, Vincent Lacoste, Marlene Ouka, Jacques Boncy, Raymond Cesaire, Bernard Liautaud, Mathieu Nacher, Georges Dos Santos
FRONTIERS IN MICROBIOLOGY
(2019)
Article
Infectious Diseases
Samantha James, Damien Donato, Benoit de Thoisy, Anne Lavergne, Vincent Lacoste
INFECTION GENETICS AND EVOLUTION
(2020)
Article
Veterinary Sciences
Manrico Sebastiano, Daniele Canestrelli, Roberta Bisconti, Anne Lavergne, Kevin Pineau, Olivier Chastel, Vincent Lacoste, David Costantini
FRONTIERS IN VETERINARY SCIENCE
(2020)
Article
Immunology
Ighor Arantes, Gonzalo Bello, Edith Darcissac, Vincent Lacoste, Mathieu Nacher
Summary: The study revealed that HIV-1 subtype B epidemic in French Guiana was distributed in various transmission clusters, with sex workers, crack-cocaine users, young individuals, and nationals or migrants from neighbouring South American countries being more likely to cluster within large/medium transmission clusters.
Article
Microbiology
Mathieu Nacher, Gersande Godefroy, Valentin Dufit, Maylis Douine, Fatiha Najioullah, Raymond Cesaire, Nadia Thomas, Kinan Drak Alsibai, Antoine Adenis, Vincent Lacoste
Article
Infectious Diseases
Edith Darcissac, Damien Donato, Benoit de Thoisy, Vincent Lacoste, Anne Lavergne
Summary: The study identified various paramyxoviruses in bats from French Guiana and revealed cross-infection of paramyxoviruses among different bat species. The results suggest a wide distribution of paramyxoviruses in Central to South America, highlighting the potential risk of cross-species transmission that warrants further investigation.
INFECTION GENETICS AND EVOLUTION
(2021)
Article
Virology
Sourakhata Tirera, Benoit de Thoisy, Damien Donato, Christiane Bouchier, Vincent Lacoste, Alain Franc, Anne Lavergne
Summary: The study characterized viral diversity in seven neotropical rodent species and explored the impact of environmental disturbance on this diversity. The results showed that viral diversity was greater in pristine habitats, lowest in peri-urban areas, and highest in savannah regions. Phylogenetic analysis highlighted the wide diversity of vertebrate-related viral families and potential transmission risks to humans. The findings provide insights into rodent virus diversity in Amazonia and emphasize the role of habitats and host dietary ecology in driving viral diversity.
Article
Biotechnology & Applied Microbiology
Derek Gatherer, Daniel P. Depledge, Carol A. Hartley, Moriah L. Szpara, Paola K. Vaz, Maria Benko, Curtis R. Brandt, Neil A. Bryant, Akbar Dastjerdi, Andor Doszpoly, Ursula A. Gompels, Naoki Inoue, Keith W. Jarosinski, Rajeev Kaul, Vincent Lacoste, Peter Norberg, Francesco C. Origgi, Richard J. Orton, Philip E. Pellett, D. Scott Schmid, Stephen J. Spatz, James P. Stewart, Jakob Trimpert, Thomas B. Waltzek, Andrew J. Davison
Summary: Members of the family Herpesviridae have complex structures and adapt well to their hosts, establishing lifelong latent infections with limited gene expression. Severe diseases are usually observed in specific populations like foetuses, infants, immunocompromised individuals, or alternative hosts. This summary is based on the ICTV Report on Herpesviridae, available at ictv.global/report/herpesviridae.
JOURNAL OF GENERAL VIROLOGY
(2021)
Article
Multidisciplinary Sciences
Sarah Temmam, Khamsing Vongphayloth, Eduard Baquero, Sandie Munier, Massimiliano Bonomi, Beatrice Regnault, Bounsavane Douangboubpha, Yasaman Karami, Delphine Chretien, Daosavanh Sanamxay, Vilakhan Xayaphet, Phetphoumin Paphaphanh, Vincent Lacoste, Somphavanh Somlor, Khaithong Lakeomany, Nothasin Phommavanh, Philippe Perot, Oceane Dehan, Faustine Amara, Flora Donati, Thomas Bigot, Michael Nilges, Felix A. Rey, Sylvie van der Werf, Paul T. Brey, Marc Eloit
Summary: SARS-CoV-2-like bat viruses that are potentially infectious for humans circulate in Rhinolophus spp. in the Indochinese peninsula, and they can enter human cells through the hACE2 pathway, indicating the need for further understanding of the origin of the epidemic.
Article
Microbiology
Elodie Calvez, Phaithong Bounmany, Charlotte Baliere, Somphavanh Somlor, Souksakhone Viengphouthong, Thonglakhone Xaybounsou, Sitsana Keosenhom, Kitphithak Fangkham, Paul T. Brey, Valerie Caro, Vincent Lacoste, Marc Grandadam
Summary: DENV-1 has been continuously circulating in Laos from 2016 to 2020 with a prevalence ranging from 16% to 22% among serotyping tests. Phylogenetic analysis revealed the presence of DENV-1 genotype I with different clusters circulating in the country since at least 2008.
Article
Multidisciplinary Sciences
Elodie Calvez, Phaithong Bounmany, Somphavanh Somlor, Thonglakhone Xaybounsou, Souksakhone Viengphouthong, Sitsana Keosenhom, Paul T. Brey, Vincent Lacoste, Marc Grandadam
Summary: This study summarized the genetic features of CHIKV strains detected in Lao PDR between 2014 and 2020, indicating multiple introductions of CHIKV in the country since 2014 and the possibility of future outbreaks.
Article
Virology
Amal Bennouna, Michael Luciano Tantely, Vololoniaina Raharinosy, Soa Fy Andriamandimby, Thomas Bigot, Delphine Chretien, Elise Jacquemet, Stevenn Volant, Sarah Temmam, Philippe Dussart, Vincent Lacoste, Romain Girod, Marc Eloit
Summary: This study analyzed the virome of mosquitoes collected in Mahajanga, Madagascar to detect known and unknown viruses and investigate the factors contributing to the low circulation of arboviruses in the area. The analysis revealed a diverse range of viral families and genera and different patterns influenced by the mosquito genus and season of collection. Despite the absence of known arboviruses, this study enhances our understanding of viral ecology and diversity within mosquito populations and provides a foundation for ongoing surveillance and preventive strategies against mosquito-borne viral diseases.
Article
Microbiology
Iony Manitra Razanajatovo, Lova Andrianomiadana, Azimdine Habib, Mirella Malala Randrianarisoa, Helisoa Razafimanjato, Maheninasy Rakotondrainipiana, Prisca Andriantsalama, Ravaka Randriamparany, Soa Fy Andriamandimby, Pascale Vonaesch, Philippe Jean Sansonetti, Vincent Lacoste, Rindra Vatosoa Randremanana, Jean-Marc Collard, Jean-Michel Heraud, Afribiota Invest
Summary: The study aimed to assess whether enteric viral carriage plays a role in stunting in poor settings. Researchers obtained stool samples from 464 healthy children aged 2 to 5 years and tested for enteric and non-enteric viruses. The results showed no direct link between stunting and enteropathogenic viral carriage.
Article
Health Care Sciences & Services
Siriphone Virachith, Virginie Pommelet, Elodie Calvez, Vilaysone Khounvisith, Somphou Sayasone, Sengchanh Kounnavong, Mayfong Mayxay, Phonepadith Xangsayarath, Sarah Temmam, Marc Eloit, Nicolas Escriou, Thierry Rose, Khamsing Vongphayloth, Judith M. Hubschen, Vincent Lacoste, Somphavanh Somlor, Darouny Phonekeo, Paul T. Brey, Antony P. Black
Summary: A seroprevalence study conducted in Laos from August to September 2020 showed no evidence of significant SARS-CoV-2 circulation before September 2020. This may be attributed to early decisive measures by the government, social behavior, and low population density.
LANCET REGIONAL HEALTH-WESTERN PACIFIC
(2021)
Article
Virology
Gonzalo Bello, Edson Delatorre, Vincent Lacoste, Edith Darcissac, Cecile Herrmann-Storck, Benoit Tressieres, Ornella Cabras, Isabelle Lamaury, Andre Cabie, Benoit Visseaux, Marie-Laure Chaix, Diane Descamps, Raymond Cesaire, Mathieu Nacher, Georges Dos Santos