Article
Parasitology
Michael J. Pipas, David R. Fowler, Katherine D. Bardsley, Berit Bangoura
Summary: The survey conducted in Wyoming suggests that gray wolves are the major definitive hosts of Echinococcus granulosus s. l., while coyotes play a lesser role and the importance of red foxes is not clear. Although the parasite is present in the region, the risk of zoonotic disease transmission does not appear to be high.
PARASITOLOGY RESEARCH
(2021)
Article
Microbiology
Jacek Karamon, Malgorzata Samorek-Pierog, Jacek Sroka, Ewa Bilska-Zajac, Joanna Dabrowska, Maciej Kochanowski, Miroslaw Rozycki, Jolanta Zdybel, Tomasz Cencek
Summary: This study aimed to confirm the presence and molecular identification of Echinococcus tapeworms in wolves from south-eastern Poland. The investigation revealed the presence of adult E. ortleppi tapeworms in wolves for the first time, with PCR and sequencing showing high similarity to E. ortleppi (G5) sequences.
Article
Agriculture, Dairy & Animal Science
Petra Bandelj, Rok Blagus, Gorazd Vengust, Diana Zele Vengust
Summary: This study molecularly tested the prevalence of Echinococcus species in Slovenian wild carnivores and found that red foxes and golden jackals were positive for Echinococcus multilocularis. The prevalence of EM was associated with the region, with higher risk of infection in central and southern Slovenia. The golden jackal may soon become an important source for human infection with EM.
Article
Agriculture, Dairy & Animal Science
Hana Tebelmann, Udo Ganslosser
Summary: Prosocial behavior is common among group-living mammals, and Canidae are known for their social organization. This case study focused on social feedback mechanisms in two groups of grey wolves, and found that bold behavior is more likely to receive prosocial responses.
Article
Immunology
Nosheen Basharat, Jadoon Khan, Irfan Ullah, Aamer Ali Shah, Ijaz Ali
Summary: In this study, the molecular characterization of human echinococcosis in the southern Punjab region of Pakistan was conducted. The majority of human infections were caused by E. granulosus s.s., followed by E. multilocularis and E. canadensis. Genotypic characterization among both human and livestock populations is needed to explore the genetic diversity of echinococcosis.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2023)
Review
Parasitology
Adriano Casulli, Alessandro Massolo, Urmas Saarma, Gerald Umhang, Federica Santolamazza, Azzurra Santoro
Summary: This study fills a knowledge gap by providing a quantitative measure of molecularly identified species and genotypes causing human cystic echinococcosis. The study identifies geographical hotspots of different Echinococcus granulosus species causing the disease and highlights data gaps.
PARASITES & VECTORS
(2022)
Article
Microbiology
Lei Chen, Mengyao Sun, Di Xu, Zenghao Gao, Yuying Shi, Shen Wang, Yiping Zhou
Summary: This study compares the gut microbiota of wild wolves, captive wolves, and domestic dogs, and finds significant differences in species diversity and functional diversity among these groups. Captive wolves are more similar to domestic dogs in terms of both species composition and function composition of intestinal microbiota, compared to wild wolves.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Geography, Physical
Lucy O. H. Flower, Danielle C. Schreve, Angela L. Lamb
Summary: This study compared stable isotope evidence from British fossil wolves, carnivore competitors, and potential prey species from three different time periods. The results showed clear patterns of changing wolf prey choice over time, with the diet of wolves shifting from small and large prey during MIS 7c-a to large prey only during MIS 5a and a broader range of large prey during MIS 3. The study also revealed a lag between changing predatory behavior and morphological response in wolves.
QUATERNARY SCIENCE REVIEWS
(2021)
Article
Parasitology
Chan Wang, Song-Hao Yang, Nan Niu, Jia Tao, Xian-Cai Du, Ji-Hui Yang, Ming-Xing Zhu, Ya-Na Wang, Wei Zhao
Summary: Immunization with rEg.P29 downregulated the expression of lncRNA028466, leading to an increased proportion of CD4(+) T cells and a modulation of Th1 and Th2 cytokine expression to mediate the immune response.
PARASITES & VECTORS
(2021)
Review
Veterinary Sciences
Ian David Woolsey, Andrea L. Miller
Summary: Echinococcus spp. have a global distribution and are of significance to human and veterinary professionals. Infections can lead to different diseases, including cystic echinococcosis and alveolar echinococcosis.
RESEARCH IN VETERINARY SCIENCE
(2021)
Article
Microbiology
Baoping Guo, Li Zhao, Lu Zhao, Rongsheng Mi, Xu Zhang, Bingjie Wang, Gang Guo, Yuan Ren, Wenjing Qi, Zhuangzhi Zhang
Summary: This study investigated the prevalence, genetic variation, and population structure of cystic echinococcosis (CE) in the Altai region of China. The infection rates were 4.52% in sheep and 4.84% in cattle. Mitochondrial cytochrome C oxidase subunit 1 (cox1) analysis revealed two genotypes, with the sheep strain (G1 genotype) being dominant. The study also showed high levels of haplotype diversity and relatively low levels of nucleotide diversity. Additionally, there was low genetic differentiation between E. granulosus s.s. populations from different regions. This research provides important information on the epidemiology and genetic structure of CE in the Altai region.
Article
Biochemistry & Molecular Biology
Yuehong Gong, Chunyan Tian, Shuai Lu, Yi Gao, Limei Wen, Bei Chen, Huijing Gao, Haibo Zhang, Jun Zhao, Jianhua Wang
Summary: The study reveals that EgRad54 knockdown combined with HM or HMD treatment enhances DNA damage in E. granulosus, inhibiting its growth. This approach works by upregulating ATM and H2A, and downregulating Rad54 and Topo2a.
DNA AND CELL BIOLOGY
(2021)
Article
Veterinary Sciences
Christian Hidalgo, Caroll Stoore, Maria Soledad Baquedano, Ismael Pereira, Carmen Franco, Marcela Hernandez, Rodolfo Paredes
Summary: Cystic echinococcosis is a zoonotic disease caused by the metacestode of Echinococcus granulosus, with cysts forming in the liver and lungs of intermediate hosts. The differentiation between fertile and non-fertile cysts is associated with distinct local immune response patterns in cattle and sheep, indicating a relationship with metacestode fertility.
VETERINARY RESEARCH
(2021)
Article
Oncology
Edgardo Berriel, Teresa Freire, Carolina Chiale, Ernesto Rodriguez, Gabriel Moron, Gabriel Fernandez-Grana, Martina Crispo, Nora Berois, Eduardo Osinaga
Summary: Echinococcus granulosus, a cestode parasite, can inhibit colon cancer growth, and also show anti-tumor activity against LL/2 lung cancer in mice by inducing antigen-specific immune responses and activating NK1.1(+) cells. This suggests that HCF vaccination can evoke an integrated anti-tumor immune response, involving both innate and adaptive components, providing novel insights into the relationship between HCF vaccination and tumor growth.
CANCER IMMUNOLOGY IMMUNOTHERAPY
(2021)
Article
Environmental Sciences
Jianjun Xu, Guoying Song, Mei Xiong, Yujing Zhang, Bamu Sanlang, Ga Long, Rulin Wang
Summary: This study used MaxEnt to predict the distribution range of E. granulosus in China and analyze the impact of environmental variables. The results provide a theoretical basis for the prevention and monitoring of echinococcosis in China.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)