Article
Engineering, Chemical
Nina Doskocz, Monika Zaleska-Radziwill
Summary: The widespread use of nanoparticles leads to their presence in wastewater and landfills, posing a potential risk to the environment. However, the harmfulness of nanoparticles is still not well understood. This study examines the genotoxicity of aluminum oxide nanoparticles (Al2O3 NPs) using Escherichia coli bacteria and erythrocytes of Cyprinus carpio. The results indicate that Al2O3 NPs can potentially cause changes in the genetic material of the bioindicators.
DESALINATION AND WATER TREATMENT
(2023)
Article
Plant Sciences
Okunola Adenrele Alabi
Summary: Concern on the toxicity of final wastewater generated by the petroleum refining industry has increased due to potential health threats. This study found that petroleum refinery wastewater is mutagenic and genotoxic, posing risks to the environment. The substances responsible for this toxicity were identified as organic compounds and heavy metals present in the wastewater.
Article
Environmental Sciences
Sardar Khan, Zahir Qamar, Ajmal Khan, Muhammad Waqas, Javed Nawab, Muhmmmad Khisroon, Ajmal Khan
Summary: This study investigated the genotoxic effects of polycyclic aromatic hydrocarbons (PAHs) present in vehicle-wash wastewater (VWW) on fish and freshwater mussels. The results showed that the genotoxicity of VWW on both fish and mussels increased with the duration of exposure, indicating the high genotoxicity of VWW and the need for treatment before discharge into aquatic ecosystems.
ENVIRONMENTAL POLLUTION
(2023)
Article
Environmental Sciences
Felipe de Araujo Nascimento, Daniela de Melo e Silva, Thays Millena Alves Pedroso, Jheneffer Sonara Aguiar Ramos, Michelle Rocha Parise
Summary: Occupational exposure to pesticides in farmers results in significant DNA damage, showing a notable impact and variability in the studies. Smokers who are occupationally exposed to pesticides have slightly reduced DNA damage compared to non-smokers, indicating some genetic toxicity. The study demonstrates a higher risk of occupationally exposed rural workers developing related diseases due to the genotoxic effect of pesticides.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Environmental Sciences
Sergey Petrovich Kukla, Victor Pavlovich Chelomin, Andrey Alexandrovich Mazur, Valentina Vladimirovna Slobodskova
Summary: This study compared the effects of zinc ions and zinc oxide nanoparticles on the sperm of marine organisms. The results showed that both pollutants caused an increase in DNA damage, and the increase in DNA damage varied with the concentration of pollutants in different experimental groups.
Article
Pharmacology & Pharmacy
Giselle S. Meireles, Rafaela Aires, Larissa Z. Coco, Edgar H. Kampke, Maria E. S. Barroso, Elisardo C. Vasquez, Thiago M. C. Pereira, Silvana S. Meyrelles, Bianca P. Campagnaro
Summary: This study found that renovascular hypertension can cause oxidative damage and impaired DNA repair in bone marrow cells, leading to compromised hematopoiesis. It provides new insights into the influence of hypertension on bone marrow homeostasis.
CLINICAL AND EXPERIMENTAL HYPERTENSION
(2022)
Article
Chemistry, Medicinal
Zeineb Marzougui, Sylvie Huet, Anne-Louise Blier, Ludovic Le Hegarat, Haifa Tounsi-Kettiti, Riadh Kharrat, Riadh Marrouchi, Valerie Fessard
Summary: In this study, the in vivo genotoxic effects of C17-sphinganine analog mycotoxin (C17-SAMT) were evaluated using comet assays and micronucleus assay. The results showed that C17-SAMT induced DNA damage in the duodenum and spleen, but had no significant effect on chromosome and genome damage in the bone marrow. Microscopic observations of the liver revealed increased mitosis and hepatocytes' cytoplasm clarification.
Article
Environmental Sciences
Claudia Castro, Ana Carvalho, Isabel Gaivao, Jose Lima-Brito
Summary: The study evaluated the tolerance of four wine-producing varieties to different concentrations of Cu by treating V. vinifera cuttings with Cu-rich hydroponic solutions. It was found that 50μM Cu treatment increased DNA damage, with 'Tinto Cao' being the most sensitive variety. Comet-FISH analysis revealed partial damage on rDNA and telomeric DNA in response to Cu treatment.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Cell Biology
Nasrin Ghassemi-Barghi, Zeynab Ehsanfar, Omid Mohammadrezakhani, Sorour Ashari, Shamim Ghiabi, Zahra Bayrami
Summary: ARA290 has been found to exert a protective effect against cisplatin-induced nephrotoxicity by anti-apoptotic, anti-inflammatory, and antioxidant mechanisms, suggesting its potential as a new therapeutic approach for acute kidney injury patients.
Article
Environmental Sciences
Ronan Adler Tavella, Caroline Lopes Feijo Fernandes, Lucia Emanueli Schimith, Lisiane Martins Volcao, Marina dos Santos, Flavio Manoel Rodrigues da Silva Junior
Summary: Socioeconomic and demographic factors, lifestyle, and cultural characteristics may have an important impact on genetic damage. This study analyzed the association between a set of factors and genetic damage by studying populations in southern Brazil. The results showed that age had a weak association with genetic damage, while factors such as skin color, occupational exposure, drug use, exposure to radiation, and the cultural habit of consuming chimarrao were found to be associated with genetic damage. Yerba mate consumption was identified as a confounding factor in cytogenetic studies in the southern region of South America.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Food Science & Technology
Concepcion Medrano-Padial, Maria Puerto, Ana Isabel Prieto, Nahum Ayala, Pauline Beaumont, Caroline Rouger, Stephanie Krisa, Silvia Pichardo
Summary: This study investigated the in vivo genotoxic effects of rats orally exposed to different doses of ST-99 and found no genotoxicity in the cells isolated from stomach, liver, and blood. Analytical studies confirmed the presence of stilbenes and their metabolites in plasma and tissues, supporting the safety profile of ST-99 for potential application as a preservative in the wine industry.
Article
Biochemistry & Molecular Biology
Galina N. Chelomina, Sergey P. Kukla, Viktor P. Chelomin, Pham N. Doanh
Summary: Parasite infection can lead to DNA damage, potentially involving oxidative stress and cancer development; these research findings are important for understanding the pathogenesis mechanisms of parasitic diseases.
Article
Chemistry, Multidisciplinary
Adriana Rodriguez-Garraus, Maria Alonso-Jauregui, Ana-Gloria Gil, Inigo Navarro-Blasco, Adela Lopez de Cerain, Amaya Azqueta
Summary: A new material composed of kaolin base with silver nanoparticles was developed as an alternative to antibiotics in animal feed. In an in vivo geno-toxicological evaluation in rats, the material showed no adverse effects when administered orally at a dose of 2000 mg/kg b.w. for 28 days. The material did not induce micronuclei or DNA damage in various tissues, and silver content in target organs confirmed the negative results.
Article
Food Science & Technology
Antonio Cascajosa-Lira, Maria Puerto, Ana I. Prieto, Silvia Pichardo, Leticia Diez-Quijada Jimenez, Alberto Banos, Enrique Guillamon, Rosario Moyano, Veronica Molina-Hernandez, Angeles Jos, Ana M. Camean
Summary: This study confirmed the lack of in vivo genotoxicity of PTS at the doses tested, indicating that it is a promising natural alternative in animal feed without adverse effects on genetic material.
Article
Nutrition & Dietetics
Lea Beltzig, Anna Frumkina, Christian Schwarzenbach, Bernd Kaina
Summary: The study compared the cytotoxic and genotoxic activity of native curcumin solubilised in ethanol (Cur-E) with curcumin embedded in micelles (Cur-M) and found that they had the same toxic effects in cells, requiring continuous exposure for inducing cell death. The effective concentration in cells was much higher than achievable in vivo, suggesting that native curcumin and curcumin in a micellar formulation at the ADI level are not cytotoxic/genotoxic, indicating a wide margin of safety.
Article
Engineering, Mechanical
Bo Yan, Xianjia Wang, Zhihao Wang, Chuanyu Wu, Wenming Zhang
Summary: This study introduces electromagnetic shunt damping to improve the traditional lever-type vibration isolator, while compensating for inherent resistance with negative resistance and resonant shunts. Experimental and numerical analyses show that parameters in the low-frequency range significantly impact vibration isolation performance.
INTERNATIONAL JOURNAL OF MECHANICAL SCIENCES
(2022)
Article
Acoustics
Bo Yan, Xiagui Pan, Ran Su, Chuanyu Wu
Summary: This study investigates the dynamics behavior of a tumbler on an arc surface. The results demonstrate the potential for designing low-frequency vibration devices and open up new possibilities for tumbler-inspired structures.
JOURNAL OF SOUND AND VIBRATION
(2022)
Article
Engineering, Mechanical
Bo Yan, Ning Yu, Hongye Ma, Chuanyu Wu
Summary: This paper presents a general theory for bistable vibration isolators (BVIs) and reveals the bistable vibration isolation mechanism. The advantages of BVIs in vibration isolation are quantitatively verified through theoretical and numerical calculations, providing guidance for the design, analysis, and optimization of BVIs.
MECHANICAL SYSTEMS AND SIGNAL PROCESSING
(2022)
Article
Engineering, Mechanical
Peng Ling, Lunlun Miao, Wenming Zhang, Chuanyu Wu, Bo Yan
Summary: This paper presents a cockroach-inspired structure for low-frequency vibration isolation. By mimicking the body topology of cockroaches, the structure exhibits nonlinear properties that can significantly reduce resonant frequency and peak transmissibility. It provides a high-stability and cost-effective solution for low-frequency vibration isolation.
MECHANICAL SYSTEMS AND SIGNAL PROCESSING
(2022)
Review
Mathematics, Applied
Bo Yan, Ning Yu, Chuanyu Wu
Summary: This article discusses the application of nonlinear vibration isolation technology in protecting host structures from harmful vibrations. Among them, the three-spring configured quasi-zero-stiffness (QZS) vibration isolator is the most widely studied object, which has negative stiffness and high-static-low-dynamic stiffness characteristics. This review also explores the basic theory, design methodology, nonlinear damping mechanism, and active control of electromagnetic QZS vibration isolators.
APPLIED MATHEMATICS AND MECHANICS-ENGLISH EDITION
(2022)
Article
Engineering, Industrial
Peilin Cheng, Yuze Ye, Bo Yan, Yebo Lu, Chuanyu Wu
Summary: This paper presents a novel soft gripper with variable gripping posture to improve the gripping adaptability. By adjusting the conversion mechanism, four different gripping postures can be achieved. The experimental results show that the quasi-static model accurately predicts the finger deformation, and the gripper has the highest gripping force under the parallel posture. The gripping adaptability is significantly enhanced by converting the gripping postures.
INDUSTRIAL ROBOT-THE INTERNATIONAL JOURNAL OF ROBOTICS RESEARCH AND APPLICATION
(2023)
Article
Physics, Applied
Peilin Cheng, Yebo Lu, Chuanyu Wu, Bo Yan
Summary: In this study, a modular and reconfigurable soft pneumatic gripper was designed, inspired by the dexterous grasping of the human hand for fruits of different shapes and sizes. The gripper comprised three soft extension actuators, two soft rotation actuators, and three soft bending actuators, which could be adjusted to hold fruits of different sizes and shapes. The deformation characteristics of these actuators were investigated experimentally.
JOURNAL OF PHYSICS D-APPLIED PHYSICS
(2023)
Article
Engineering, Mechanical
Xuefeng Li, Daniil Yurchenko, Renfu Li, Xingxing Feng, Bo Yan, Kai Yang
Summary: This paper proposes a novel bistable energy harvester coupled with a nonlinear elastic boundary to enhance energy harvesting performance. Experimental results show that the proposed structure outperforms its counterparts in terms of power output and operational bandwidth. Furthermore, bifurcation analyses and basin of attraction calculation are conducted to identify the optimal parameters and investigate the influence of initial conditions, providing practical design guidelines for improving the system's performance.
MECHANICAL SYSTEMS AND SIGNAL PROCESSING
(2023)
Article
International Relations
Duong Thi Thuy Mai, Bo Yan
Summary: This paper provides a historical overview of the divergences between the EU and China in reducing global aviation emissions, focusing on three specific issues: the framework to tackle emissions, the reflection of CBDR-RC principle in MBMs, and the role of ICAO. It explains the driving forces behind these divergences, such as state sovereignty, fairness of burden sharing, and competitiveness. These divergences are influenced by perceptions of leading role, targets in global climate governance, and compatibility with current climate policies.
ASIA EUROPE JOURNAL
(2023)
Article
Obstetrics & Gynecology
Bo Yan, Bin Wu, Zhi-Qiang Wang, Yan Wei, Ya-Li Ni
Summary: This study investigated the peripheral blood transcriptome of patients with ovarian hyperstimulation syndrome (OHSS) using high-throughput sequencing. Several differentially expressed genes (DEGs) related to OHSS risk factors were identified, suggesting their potential as biomarkers for future OHSS research.
REPRODUCTIVE AND DEVELOPMENTAL MEDICINE
(2023)
Article
Instruments & Instrumentation
Huanguo Chen, Xu Miao, Wentao Mao, Shoujun Zhao, Gaopeng Yang, Yan Bo
Summary: An electro-hydrostatic actuator (EHA) fault diagnosis method based on few-shot data augmentation is proposed to diagnose and isolate potential faults. The method highlights the time series characteristics and correlation between different signals by converting multi-dimensional experimental data into grayscale data and extracting local features. The diagnostic model, combining Wasserstein deep convolutional generative adversarial network (WDCGAN) with stacked denoised auto encoder (SDAE), effectively identifies typical fault modes of EHA with high accuracy and strong feature extraction ability compared to five commonly used fault classification methods.
SMART MATERIALS AND STRUCTURES
(2023)
Article
Environmental Sciences
Honglin Zhu, Huizeng Liu, Qiming Zhou, Aihong Cui
Summary: This study presents a framework combining machine learning-based downscaling algorithm, residual correction, and precipitation calibration for accurate high-resolution precipitation estimation. The results show that the machine learning-based methods outperform conventional approaches, with spatial random forest and eXtreme gradient boosting performing the best in generating high-resolution precipitation. The geographical difference analysis calibration process significantly improves the downscaled results.
Article
Acoustics
Hongye Ma, Ke Wang, Haifeng Zhao, Chong Zhao, Jing Xue, Chao Liang, Bo Yan
Summary: This paper proposes a tunable local resonance metamaterial with chiral buckling structures for low-frequency vibration isolation. The unit cell consists of the inner and outer buckling stiffness structure, basic structure, and local resonator. The bistability of the unit cells with different initial shapes of beams is investigated and compared. The dynamic responses of the metamaterial with simple unit cells and hybrid supercells are derived and analyzed. The results show that the unit cell with initially convex downward beams has strong bistability and determinate deformation modes. The metamaterial with simple unit cells has tunable and wide band gap and low-frequency vibration isolation. The metamaterial with hybrid supercells can further broaden the band gap width and lower the band gap frequency, which has up to 16 different band gap characteristics.
JOURNAL OF SOUND AND VIBRATION
(2023)
Article
Acoustics
Peng Ling, Lunlun Miao, Bingliang Ye, Jin You, Wenming Zhang, Bo Yan
Summary: Inspired by the three postures of a click beetle, a novel passive click-beetle-inspired structure (CBIS) with variable asymmetric stiffness characteristics is proposed and systematically investigated for stiffness tunning and low-frequency vibration isolation. The stiffness of CBIS can be easily tuned among negative, quasi-zero, zero, small positive by the initial assembly angle, length ratio and linear stiffness ratio. The zero stiffness (ZS) or quasi-zero stiffness (QZS) region of CBIS can be extremely huge under some special parameters, which can broaden the working range of CBIS and benefit to large-deflection vibration isolation. The proposed CBIS opens a new route towards tunning asymmetric stiffness for low frequency vibration isolation.
JOURNAL OF SOUND AND VIBRATION
(2023)
Article
Automation & Control Systems
Bo Yan, Peng Ling, Lunlun Miao, Ning Yu, Jiaojiao Sun, Qinchuan Li
Summary: This work presents a cockroach-inspired structure coupled with electromagnetic shunt damping (EMSD) for ultra-low frequency vibration isolation. The EMSD includes linear damping and nonlinear damping achieved through geometric nonlinearity. By adjusting the geometric parameters and assembly configuration, the electromagnetic coupling coefficient can be increased, resulting in enhanced equivalent damping. Experimental results demonstrate the effectiveness of EMSD in reducing the transmission rate of ultra-low frequency vibration without significant impact on high-frequency vibration isolation.
IEEE-ASME TRANSACTIONS ON MECHATRONICS
(2023)