Kinesin, 30 years later: Recent insights from structural studies

Structural Basis of New Allosteric Inhibition in Kinesin Spindle Protein Eg5

(2015) Hideshi Yokoyama et al.   ACS Chemical Biology

KIF14 Binds Tightly to Microtubules and Adopts a Rigor-Like Conformation

(2014) Kritica Arora et al.   JOURNAL OF MOLECULAR BIOLOGY

Kinesin processivity is gated by phosphate release

(2014) Bojan Milic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The structure of apo-kinesin bound to tubulin links the nucleotide cycle to movement

(2014) Luyan Cao et al.   Nature Communications

High-resolution structures of kinesin on microtubules provide a basis for nucleotide-gated force-generation

(2014) Zhiguo Shang et al.   eLife

Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins

(2014) Joseph Atherton et al.   eLife

“Snapshots” of Ispinesib-induced Conformational Changes in the Mitotic Kinesin Eg5

(2013) Hung Yi Kristal Kaan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Force generation by kinesin and myosin cytoskeletal motor proteins

(2013) F. Jon Kull et al.   JOURNAL OF CELL SCIENCE

Structural Insights into a Unique Inhibitor Binding Pocket in Kinesin Spindle Protein

(2013) Venkatasubramanian Ulaganathan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Functions and mechanics of dynein motor proteins

(2013) Anthony J. Roberts et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Structure of a kinesin–tubulin complex and implications for kinesin motility

(2013) Benoît Gigant et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of the Rigor Actin-Tropomyosin-Myosin Complex

(2012) Elmar Behrmann et al.   CELL

A universal pathway for kinesin stepping

(2011) Bason E Clancy et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Elucidating the functionality of kinesins: An overview of small molecule inhibitors

(2011) James A.D. Good et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

ATP Hydrolysis in Eg5 Kinesin Involves a Catalytic Two-water Mechanism

(2009) Courtney L. Parke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Direct observation of the binding state of the kinesin head to the microtubule

(2009) Nicholas R. Guydosh et al.   NATURE

Kinesin superfamily motor proteins and intracellular transport

(2009) Nobutaka Hirokawa et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Why kinesin is so processive

(2009) E. Toprak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structures of kinesin motor proteins

(2009) Alexander Marx et al.   CELL MOTILITY AND THE CYTOSKELETON

Allosteric Communication in Myosin V: From Small Conformational Changes to Large Directed Movements

(2008) M. Cecchini et al.   PLoS Computational Biology