Single-Domain Antibodies Targeting Neuraminidase Protect against an H5N1 Influenza Virus Challenge

A Systems Analysis Identifies a Feedforward Inflammatory Circuit Leading to Lethal Influenza Infection

(2013) Marlène Brandes et al.   CELL

The Universal Epitope of Influenza A Viral Neuraminidase Fundamentally Contributes to Enzyme Activity and Viral Replication

(2013) Tracey M. Doyle et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Basis for Broad Neuraminidase Immunity: Conserved Epitopes in Seasonal and Pandemic H1N1 as Well as H5N1 Influenza Viruses

(2013) H. Wan et al.   JOURNAL OF VIROLOGY

Clinical Findings in 111 Cases of Influenza A (H7N9) Virus Infection

(2013) Hai-Nv Gao et al.   NEW ENGLAND JOURNAL OF MEDICINE

Fusion of an Fc chain to a VHH boosts the accumulation levels inArabidopsisseeds

(2013) Sylvie De Buck et al.   PLANT BIOTECHNOLOGY JOURNAL

Generation of VHH antibodies against the Arabidopsis thaliana seed storage proteins

(2013) Thomas De Meyer et al.   PLANT MOLECULAR BIOLOGY

Formatted single-domain antibodies can protect mice against infection with influenza virus (H5N2)

(2012) Sergei V. Tillib et al.   ANTIVIRAL RESEARCH

Decreased Neuraminidase Activity Is Important for the Adaptation of H5N1 Influenza Virus to Human Airway Epithelium

(2012) N. A. Ilyushina et al.   JOURNAL OF VIROLOGY

Natural and long-lasting cellular immune responses against influenza in the M2e-immune host

(2012) M Schotsaert et al.   Mucosal Immunology

Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets

(2012) Masaki Imai et al.   NATURE

Contribution of antibody production against neuraminidase to the protection afforded by influenza vaccines

(2012) Glendie Marcelin et al.   REVIEWS IN MEDICAL VIROLOGY

Airborne Transmission of Influenza A/H5N1 Virus Between Ferrets

(2012) S. Herfst et al.   SCIENCE

Nanobodies®: New ammunition to battle viruses

(2011) Peter Vanlandschoot et al.   ANTIVIRAL RESEARCH

An influenza N1 neuraminidase-specific monoclonal antibody with broad neuraminidase inhibition activity against H5N1 HPAI viruses

(2011) Yoko Shoji et al.   Human vaccines & immunotherapeutics

Continued evolution of highly pathogenic avian influenza A (H5N1): updated nomenclature

(2011)   Influenza and Other Respiratory Viruses

Influenza neuraminidase

(2011) Gillian M. Air   Influenza and Other Respiratory Viruses

Nanobodies® Specific for Respiratory Syncytial Virus Fusion Protein Protect Against Infection by Inhibition of Fusion

(2011) Bert Schepens et al.   JOURNAL OF INFECTIOUS DISEASES

Nanobodies With In Vitro Neutralizing Activity Protect Mice Against H5N1 Influenza Virus Infection

(2011) Lorena Itatí Ibañez et al.   JOURNAL OF INFECTIOUS DISEASES

Structure of a nanobody-stabilized active state of the β2 adrenoceptor

(2011) Søren G. F. Rasmussen et al.   NATURE

Influenza A Virus Hemagglutinin Antibody Escape Promotes Neuraminidase Antigenic Variation and Drug Resistance

(2011) Scott E. Hensley et al.   PLoS One

Llama-Derived Single Domain Antibodies to Build Multivalent, Superpotent and Broadened Neutralizing Anti-Viral Molecules

(2011) Anna Hultberg et al.   PLoS One

Potent Neutralization of Influenza A Virus by a Single-Domain Antibody Blocking M2 Ion Channel Protein

(2011) Guowei Wei et al.   PLoS One

Production of antibodies in plants: status after twenty years

(2010) Benoit De Muynck et al.   PLANT BIOTECHNOLOGY JOURNAL

Qualitative and quantitative analyses of virtually all subtypes of influenza A and B viral neuraminidases using antibodies targeting the universally conserved sequences

(2010) Caroline Gravel et al.   VACCINE

Pandemic preparedness: Toward a universal influenza vaccine

(2009) K. Roose et al.   DRUG NEWS & PERSPECTIVES

Protective Immunity Afforded by Inactivated H5N1 (NIBRG‐14) Vaccine Requires Antibodies against Both Hemagglutinin and Neuraminidase in Mice

(2009) Yoshimasa Takahashi et al.   JOURNAL OF INFECTIOUS DISEASES

Neuraminidase Stalk Length and Additional Glycosylation of the Hemagglutinin Influence the Virulence of Influenza H5N1 Viruses for Mice

(2009) Y. Matsuoka et al.   JOURNAL OF VIROLOGY

Geographic Dependence, Surveillance, and Origins of the 2009 Influenza A (H1N1) Virus

(2009) Vladimir Trifonov et al.   NEW ENGLAND JOURNAL OF MEDICINE

MDCK cells that express proteases TMPRSS2 and HAT provide a cell system to propagate influenza viruses in the absence of trypsin and to study cleavage of HA and its inhibition

(2009) Eva Böttcher et al.   VACCINE

A practical influenza neutralization assay to simultaneously quantify hemagglutinin and neuraminidase-inhibiting antibody responses

(2009) Arash Hassantoufighi et al.   VACCINE

A high dosage influenza vaccine induced significantly more neuraminidase antibody than standard vaccine among elderly subjects

(2009) Thomas R. Cate et al.   VACCINE

Head-to-tail fusions of camelid antibodies can be expressed in planta and bind in rumen fluid

(2008) Somrutai Winichayakul et al.   BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

Single-domain antibodies as building blocks for novel therapeutics

(2008) D SAERENS et al.   CURRENT OPINION IN PHARMACOLOGY

An Influenza A Vaccine Based on Tetrameric Ectodomain of Matrix Protein 2

(2008) Marina De Filette et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Influenza A Virus Neuraminidase Limits Viral Superinfection

(2008) I-C. Huang et al.   JOURNAL OF VIROLOGY

Rapid and reliable universal cloning of influenza A virus genes by target-primed plasmid amplification

(2008) J. Stech et al.   NUCLEIC ACIDS RESEARCH