Exposure of Epitope Residues on the Outer Face of the Chikungunya Virus Envelope Trimer Determines Antibody Neutralizing Efficacy

A high-throughput shotgun mutagenesis approach to mapping B-cell antibody epitopes

(2014) Edgar Davidson et al.   IMMUNOLOGY

Chikungunya Viruses That Escape Monoclonal Antibody Therapy Are Clinically Attenuated, Stable, and Not Purified in Mosquitoes

(2014) P. Pal et al.   JOURNAL OF VIROLOGY

Crippling Virus Set to Conquer Western Hemisphere

(2014) M. Enserink   SCIENCE

Neutralizing monoclonal antibodies to the E2 protein of chikungunya virus protects against disease in a mouse model

(2013) Lucas Y.H. Goh et al.   CLINICAL IMMUNOLOGY

Chikungunya virus: an update on antiviral development and challenges

(2013) Parveen Kaur et al.   DRUG DISCOVERY TODAY

Characterisation of mouse monoclonal antibodies targeting linear epitopes on Chikungunya virus E2 glycoprotein

(2013) Chong Long Chua et al.   JOURNAL OF VIROLOGICAL METHODS

Atomic-level functional model of dengue virus Envelope protein infectivity

(2013) E. A. Christian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Novel vaccine against Venezuelan equine encephalitis combines advantages of DNA immunization and a live attenuated vaccine

(2013) Irina Tretyakova et al.   VACCINE

IRES-based Venezuelan equine encephalitis vaccine candidate elicits protective immunity in mice

(2013) Shannan L. Rossi et al.   VIROLOGY

Chikungunya virus with E1-A226V mutation causing two outbreaks in 2010, Guangdong, China

(2013) De Wu et al.   Virology Journal

A Neutralizing Monoclonal Antibody Targeting the Acid-Sensitive Region in Chikungunya Virus E2 Protects from Disease

(2013) Suganya Selvarajah et al.   PLoS Neglected Tropical Diseases

Development of a Highly Protective Combination Monoclonal Antibody Therapy against Chikungunya Virus

(2013) Pankaj Pal et al.   PLoS Pathogens

Structural analyses at pseudo atomic resolution of Chikungunya virus and antibodies show mechanisms of neutralization

(2013) Siyang Sun et al.   eLife

Early neutralizing IgG response to Chikungunya virus in infected patients targets a dominant linear epitope on the E2 glycoprotein

(2012) Yiu-Wing Kam et al.   EMBO Molecular Medicine

Chikungunya virus and prospects for a vaccine

(2012) Scott C Weaver et al.   Expert Review of Vaccines

Use of Human Monoclonal Antibodies to Treat Chikungunya Virus Infection

(2012) Jan Fric et al.   JOURNAL OF INFECTIOUS DISEASES

Longitudinal Analysis of the Human Antibody Response to Chikungunya Virus Infection: Implications for Serodiagnosis and Vaccine Development

(2012) Y.-W. Kam et al.   JOURNAL OF VIROLOGY

Isolation and Characterisation of a Human-Like Antibody Fragment (scFv) That Inactivates VEEV In Vitro and In Vivo

(2012) Torsten Rülker et al.   PLoS One

Cross-protective immunity against o‘nyong-nyong virus afforded by a novel recombinant chikungunya vaccine

(2012) Charalambos D. Partidos et al.   VACCINE

A humanised murine monoclonal antibody protects mice from Venezuelan equine encephalitis virus, Everglades virus and Mucambo virus when administered up to 48h after airborne challenge

(2012) Lyn M. O'Brien et al.   VIROLOGY

Chikungunya Virus Envelope-Specific Human Monoclonal Antibodies with Broad Neutralization Potency

(2011) L. Warter et al.   JOURNAL OF IMMUNOLOGY

Chikungunya: a re-emerging virus

(2011) Felicity J Burt et al.   LANCET

Inhibitors of Alphavirus Entry and Replication Identified with a Stable Chikungunya Replicon Cell Line and Virus-Based Assays

(2011) Leena Pohjala et al.   PLoS One

Dengue Reporter Virus Particles for Measuring Neutralizing Antibodies against Each of the Four Dengue Serotypes

(2011) Kimberly Mattia et al.   PLoS One

A complex adenovirus vaccine against chikungunya virus provides complete protection against viraemia and arthritis

(2011) Danher Wang et al.   VACCINE

Treatment of mice with human monoclonal antibody 24h after lethal aerosol challenge with virulent Venezuelan equine encephalitis virus prevents disease but not infection

(2011) Ann R. Hunt et al.   VIROLOGY

Chikungunya Virus Neutralization Antigens and Direct Cell-to-Cell Transmission Are Revealed by Human Antibody-Escape Mutants

(2011) Chia Yin Lee et al.   PLoS Pathogens

Chikungunya Virus Arthritis in Adult Wild-Type Mice

(2010) J. Gardner et al.   JOURNAL OF VIROLOGY

Glycoprotein organization of Chikungunya virus particles revealed by X-ray crystallography

(2010) James E. Voss et al.   NATURE

Structural changes of envelope proteins during alphavirus fusion

(2010) Long Li et al.   NATURE

A virus-like particle vaccine for epidemic Chikungunya virus protects nonhuman primates against infection

(2010) Wataru Akahata et al.   NATURE MEDICINE

Biology and pathogenesis of chikungunya virus

(2010) Olivier Schwartz et al.   NATURE REVIEWS MICROBIOLOGY

The First Human Epitope Map of the Alphaviral E1 and E2 Proteins Reveals a New E2 Epitope with Significant Virus Neutralizing Activity

(2010) Ann R. Hunt et al.   PLoS Neglected Tropical Diseases

Prophylaxis and Therapy for Chikungunya Virus Infection

(2009) Thérèse Couderc et al.   JOURNAL OF INFECTIOUS DISEASES

Atomic-Level Mapping of Antibody Epitopes on a GPCR

(2009) Cheryl Paes et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Characterization of Chikungunya pseudotyped viruses: Identification of refractory cell lines and demonstration of cellular tropism differences mediated by mutations in E1 glycoprotein

(2009) Beatriz Salvador et al.   VIROLOGY

Sindbis Virus Conformational Changes Induced by a Neutralizing Anti-E1 Monoclonal Antibody

(2008) R. Hernandez et al.   JOURNAL OF VIROLOGY

ENTOMOLOGY: A Mosquito Goes Global

(2008) M. Enserink   SCIENCE

Chikungunya virus adapts to tiger mosquito via evolutionary convergence: a sign of things to come?

(2008) Xavier de Lamballerie et al.   Virology Journal