The Hop-Like Stress-Induced Protein 1 Cochaperone Is a Novel Cell-Intrinsic Restriction Factor for Mitochondrial Tombusvirus Replication

The Expanding Functions of Cellular Helicases: The Tombusvirus RNA Replication Enhancer Co-opts the Plant eIF4AIII-Like AtRH2 and the DDX5-Like AtRH5 DEAD-Box RNA Helicases to Promote Viral Asymmetric RNA Replication

(2014) Nikolay Kovalev et al.   PLoS Pathogens

Noncanonical Role for the Host Vps4 AAA+ ATPase ESCRT Protein in the Formation of Tomato Bushy Stunt Virus Replicase

(2014) Daniel Barajas et al.   PLoS Pathogens

Genome-Wide RNAi Screen Identifies Broadly-Acting Host Factors That Inhibit Arbovirus Infection

(2014) Ari Yasunaga et al.   PLoS Pathogens

Viruses and antiviral immunity in Drosophila

(2013) Jie Xu et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Chaperone-Interacting TPR Proteins in Caenorhabditis elegans

(2013) Veronika Haslbeck et al.   JOURNAL OF MOLECULAR BIOLOGY

Identification of Novel Host Factors via Conserved Domain Search: Cns1 Cochaperone Is a Novel Restriction Factor of Tombusvirus Replication in Yeast

(2013) Jing-Yi Lin et al.   JOURNAL OF VIROLOGY

Cyclophilin A Binds to the Viral RNA and Replication Proteins, Resulting in Inhibition of Tombusviral Replicase Assembly

(2013) N. Kovalev et al.   JOURNAL OF VIROLOGY

Characterization of dominant-negative and temperature-sensitive mutants of tombusvirus replication proteins affecting replicase assembly

(2013) Kunj B. Pathak et al.   VIROLOGY

Colonic amyloidosis, computational analysis of the major amyloidogenic species, Serum Amyloid A

(2012) Erik Nordling et al.   COMPUTATIONAL BIOLOGY AND CHEMISTRY

Hsp70 Protein Complexes as Drug Targets

(2012) Victoria A. Assimon et al.   CURRENT PHARMACEUTICAL DESIGN

The architecture of functional modules in the Hsp90 co-chaperone Sti1/Hop

(2012) Andreas B Schmid et al.   EMBO JOURNAL

Dynamics of the regulation of Hsp90 by the co-chaperone Sti1

(2012) Chung-Tien Lee et al.   EMBO JOURNAL

Tetratricopeptide Repeat Motifs in the World of Bacterial Pathogens: Role in Virulence Mechanisms

(2012) Lukas Cerveny et al.   INFECTION AND IMMUNITY

Mapping of Chikungunya Virus Interactions with Host Proteins Identified nsP2 as a Highly Connected Viral Component

(2012) M. Bourai et al.   JOURNAL OF VIROLOGY

Global Secretome Characterization of Herpes Simplex Virus 1-Infected Human Primary Macrophages

(2012) J. J. Miettinen et al.   JOURNAL OF VIROLOGY

p33-Independent Activation of a Truncated p92 RNA-Dependent RNA Polymerase of Tomato Bushy Stunt Virus in Yeast Cell-Free Extract

(2012) J. Pogany et al.   JOURNAL OF VIROLOGY

Authentic In Vitro Replication of Two Tombusviruses in Isolated Mitochondrial and Endoplasmic Reticulum Membranes

(2012) K. Xu et al.   JOURNAL OF VIROLOGY

Proteome-Wide Overexpression of Host Proteins for Identification of Factors Affecting Tombusvirus RNA Replication: an Inhibitory Role of Protein Kinase C

(2012) M. Shah Nawaz-ul-Rehman et al.   JOURNAL OF VIROLOGY

Sensing of RNA Viruses: a Review of Innate Immune Receptors Involved in Recognizing RNA Virus Invasion

(2012) S. Jensen et al.   JOURNAL OF VIROLOGY

Yeast screens for host factors in positive-strand RNA virus replication based on a library of temperature-sensitive mutants

(2012) Muhammad Shah Nawaz-ul-Rehman et al.   METHODS

A Role for Fkbp6 and the Chaperone Machinery in piRNA Amplification and Transposon Silencing

(2012) Jordi Xiol et al.   MOLECULAR CELL

The p53 cofactor Strap exhibits an unexpected TPR motif and oligonucleotide-binding (OB)-fold structure

(2012) C. J. Adams et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell-intrinsic innate immune control of West Nile virus infection

(2012) Michael S. Diamond et al.   TRENDS IN IMMUNOLOGY

Similar roles for yeast Dbp2 and Arabidopsis RH20 DEAD-box RNA helicases to Ded1 helicase in tombusvirus plus-strand synthesis

(2012) Nikolay Kovalev et al.   VIROLOGY

An inhibitory function of WW domain-containing host proteins in RNA virus replication

(2012) Jun Qin et al.   VIROLOGY

Composition of plant virus RNA replicase complexes

(2012) Akira Mine et al.   Current Opinion in Virology

Host factors with regulatory roles in tombusvirus replication

(2012) Peter D Nagy et al.   Current Opinion in Virology

Interferon-Induced Ifit2/ISG54 Protects Mice from Lethal VSV Neuropathogenesis

(2012) Volker Fensterl et al.   PLoS Pathogens

A Co-Opted DEAD-Box RNA Helicase Enhances Tombusvirus Plus-Strand Synthesis

(2012) Nikolay Kovalev et al.   PLoS Pathogens

The TPR Domain in the Host Cyp40-like Cyclophilin Binds to the Viral Replication Protein and Inhibits the Assembly of the Tombusviral Replicase

(2012) Jing-Yi Lin et al.   PLoS Pathogens

Exploitation of cellular pathways by Dengue virus

(2011) Wolfgang Fischl et al.   CURRENT OPINION IN MICROBIOLOGY

Cyclophilin 40 facilitates HSP90-mediated RISC assembly in plants

(2011) Taichiro Iki et al.   EMBO JOURNAL

FKBP38 Peptidylprolyl Isomerase Promotes the Folding of Cystic Fibrosis Transmembrane Conductance Regulator in the Endoplasmic Reticulum

(2011) Yeshavanth K. Banasavadi-Siddegowda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IFN-Induced TPR Protein IFIT3 Potentiates Antiviral Signaling by Bridging MAVS and TBK1

(2011) X.-Y. Liu et al.   JOURNAL OF IMMUNOLOGY

Direct Interaction of Baculovirus Capsid Proteins VP39 and EXON0 with Kinesin-1 in Insect Cells Determined by Fluorescence Resonance Energy Transfer-Fluorescence Lifetime Imaging Microscopy

(2011) J. O. Danquah et al.   JOURNAL OF VIROLOGY

Defining the Roles of cis-Acting RNA Elements in Tombusvirus Replicase Assembly In Vitro

(2011) K. B. Pathak et al.   JOURNAL OF VIROLOGY

Direct Inhibition of Tombusvirus Plus-Strand RNA Synthesis by a Dominant Negative Mutant of a Host Metabolic Enzyme, Glyceraldehyde-3-Phosphate Dehydrogenase, in Yeast and Plants

(2011) T.-S. Huang et al.   JOURNAL OF VIROLOGY

Cytosolic HSP90 Cochaperones HOP and FKBP Interact with Freshly Synthesized Chloroplast Preproteins of Arabidopsis

(2011) Christine Fellerer et al.   Molecular Plant

IFIT1 is an antiviral protein that recognizes 5′-triphosphate RNA

(2011) Andreas Pichlmair et al.   NATURE IMMUNOLOGY

The dependence of viral RNA replication on co-opted host factors

(2011) Peter D. Nagy et al.   NATURE REVIEWS MICROBIOLOGY

Diverse roles of host RNA binding proteins in RNA virus replication

(2011) Zhenghe Li et al.   RNA Biology

Emerging picture of host chaperone and cyclophilin roles in RNA virus replication

(2011) P.D. Nagy et al.   VIROLOGY

Non-template functions of the viral RNA in plant RNA virus replication

(2011) Kunj B Pathak et al.   Current Opinion in Virology

Innate and adaptive immune responses to viral infection and vaccination

(2011) Taiki Aoshi et al.   Current Opinion in Virology

Synergistic Roles of Eukaryotic Translation Elongation Factors 1Bγ and 1A in Stimulation of Tombusvirus Minus-Strand Synthesis

(2011) Zsuzsanna Sasvari et al.   PLoS Pathogens

The Hop/Sti1-Hsp90 Chaperone Complex Facilitates the Maturation and Transport of a PAMP Receptor in Rice Innate Immunity

(2010) Letian Chen et al.   Cell Host & Microbe

Cytoplasmic Viral Replication Complexes

(2010) Johan A. den Boon et al.   Cell Host & Microbe

Increased expression of co-chaperone HOP with HSP90 and HSC70 and complex formation in human colonic carcinoma

(2010) Hiroshi Kubota et al.   CELL STRESS & CHAPERONES

Versatile TPR domains accommodate different modes of target protein recognition and function

(2010) Rudi Kenneth Allan et al.   CELL STRESS & CHAPERONES

Dissecting Virus-Plant Interactions Through Proteomics Approaches

(2010) Kai Xu et al.   Current Proteomics

The Interferon Stimulated Gene 54 Promotes Apoptosis

(2010) Marcin Stawowczyk et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interaction of Poxvirus Intracellular Mature Virion Proteins with the TPR Domain of Kinesin Light Chain in Live Infected Cells Revealed by Two-Photon-Induced Fluorescence Resonance Energy Transfer Fluorescence Lifetime Imaging Microscopy

(2010) A. Jeshtadi et al.   JOURNAL OF VIROLOGY

Sti1 Regulation of Hsp70 and Hsp90 Is Critical for Curing of Saccharomyces cerevisiae [PSI+] Prions by Hsp104

(2010) M. Reidy et al.   MOLECULAR AND CELLULAR BIOLOGY

Gymnastics of Molecular Chaperones

(2010) Matthias P. Mayer   MOLECULAR CELL

2′-O methylation of the viral mRNA cap evades host restriction by IFIT family members

(2010) Stephane Daffis et al.   NATURE

HSP90 at the hub of protein homeostasis: emerging mechanistic insights

(2010) Mikko Taipale et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The HSP70 chaperone machinery: J proteins as drivers of functional specificity

(2010) Harm H. Kampinga et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

In Silico Identification of Carboxylate Clamp Type Tetratricopeptide Repeat Proteins in Arabidopsis and Rice As Putative Co-Chaperones of Hsp90/Hsp70

(2010) Bishun D. Prasad et al.   PLoS One

Cpr1 cyclophilin and Ess1 parvulin prolyl isomerases interact with the tombusvirus replication protein and inhibit viral replication in yeast model host

(2010) Venugopal Mendu et al.   VIROLOGY

RNA chaperone activity of the tombusviral p33 replication protein facilitates initiation of RNA synthesis by the viral RdRp in vitro

(2010) Jozsef Stork et al.   VIROLOGY

Translation Elongation Factor 1A Facilitates the Assembly of the Tombusvirus Replicase and Stimulates Minus-Strand Synthesis

(2010) Zhenghe Li et al.   PLoS Pathogens

Pathogenesis of Flavivirus Infections: Using and Abusing the Host Cell

(2009) Maria-Dolores Fernandez-Garcia et al.   Cell Host & Microbe

A Functional Genomic Screen Identifies Cellular Cofactors of Hepatitis C Virus Replication

(2009) Andrew W. Tai et al.   Cell Host & Microbe

A Targeted Analysis of Cellular Chaperones Reveals Contrasting Roles for Heat Shock Protein 70 in Flock House Virus RNA Replication

(2009) S. A. Weeks et al.   JOURNAL OF VIROLOGY

A Key Role for Heat Shock Protein 70 in the Localization and Insertion of Tombusvirus Replication Proteins to Intracellular Membranes

(2009) R. Y.-L. Wang et al.   JOURNAL OF VIROLOGY

The Nedd4-Type Rsp5p Ubiquitin Ligase Inhibits Tombusvirus Replication by Regulating Degradation of the p92 Replication Protein and Decreasing the Activity of the Tombusvirus Replicase

(2009) D. Barajas et al.   JOURNAL OF VIROLOGY

Discovery of insect and human dengue virus host factors

(2009) October M. Sessions et al.   NATURE

A genome-wide genetic screen for host factors required for hepatitis C virus propagation

(2009) Q. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Silencing of Nicotiana benthamiana Xrn4p exoribonuclease promotes tombusvirus RNA accumulation and recombination

(2009) Hannah M. Jaag et al.   VIROLOGY

A temperature sensitive mutant of heat shock protein 70 reveals an essential role during the early steps of tombusvirus replication

(2009) Robert Yung-Liang Wang et al.   VIROLOGY

Translation elongation factor 1A is a component of the tombusvirus replicase complex and affects the stability of the p33 replication co-factor

(2009) Zhenghe Li et al.   VIROLOGY

Nucleolin/Nsr1p binds to the 3′ noncoding region of the tombusvirus RNA and inhibits replication

(2009) Yi Jiang et al.   VIROLOGY

A Unique Role for the Host ESCRT Proteins in Replication of Tomato bushy stunt virus

(2009) Daniel Barajas et al.   PLoS Pathogens

Yeast as a Model Host to Explore Plant Virus-Host Interactions

(2008) Peter D. Nagy   Annual Review of Phytopathology

Localization of the Carnation Italian ringspot virus replication protein p36 to the mitochondrial outer membrane is mediated by an internal targeting signal and the TOM complex

(2008) Yeen Hwang et al.   BMC CELL BIOLOGY

Tomato bushy stunt virus Co-Opts the RNA-Binding Function of a Host Metabolic Enzyme for Viral Genomic RNA Synthesis

(2008) Robert Yung-Liang Wang et al.   Cell Host & Microbe

Authentic Replication and Recombination of Tomato Bushy Stunt Virus RNA in a Cell-Free Extract from Yeast

(2008) J. Pogany et al.   JOURNAL OF VIROLOGY

Cdc34p Ubiquitin-Conjugating Enzyme Is a Component of the Tombusvirus Replicase Complex and Ubiquitinates p33 Replication Protein

(2008) Z. Li et al.   JOURNAL OF VIROLOGY

RNA interference screen for human genes associated with West Nile virus infection

(2008) Manoj N. Krishnan et al.   NATURE

Modification of intracellular membrane structures for virus replication

(2008) Sven Miller et al.   NATURE REVIEWS MICROBIOLOGY

In vitro assembly of the Tomato bushy stunt virus replicase requires the host Heat shock protein 70

(2008) J. Pogany et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heat shock 70 protein interaction with Turnip mosaic virus RNA-dependent RNA polymerase within virus-induced membrane vesicles

(2008) Philippe J. Dufresne et al.   VIROLOGY

The host Pex19p plays a role in peroxisomal localization of tombusvirus replication proteins

(2008) Kunj B. Pathak et al.   VIROLOGY