Proteolytic Activation of the Porcine Epidemic Diarrhea Coronavirus Spike Fusion Protein by Trypsin in Cell Culture

Proteolytic activation of the SARS-coronavirus spike protein: Cutting enzymes at the cutting edge of antiviral research

(2013) Graham Simmons et al.   ANTIVIRAL RESEARCH

TMPRSS2 Activates the Human Coronavirus 229E for Cathepsin-Independent Host Cell Entry and Is Expressed in Viral Target Cells in the Respiratory Epithelium

(2013) S. Bertram et al.   JOURNAL OF VIROLOGY

The Spike Protein of the Emerging Betacoronavirus EMC Uses a Novel Coronavirus Receptor for Entry, Can Be Activated by TMPRSS2, and Is Targeted by Neutralizing Antibodies

(2013) S. Gierer et al.   JOURNAL OF VIROLOGY

Manipulation of the Porcine Epidemic Diarrhea Virus Genome Using Targeted RNA Recombination

(2013) Chunhua Li et al.   PLoS One

Origin, Evolution, and Genotyping of Emergent Porcine Epidemic Diarrhea Virus Strains in the United States

(2013) Y.-W. Huang et al.   mBio

Host Cell Entry of Respiratory Syncytial Virus Involves Macropinocytosis Followed by Proteolytic Activation of the F Protein

(2013) Magdalena Anna Krzyzaniak et al.   PLoS Pathogens

Serine proteases of small intestine mucosa — localization, functional properties, and physiological role

(2012) T. S. Zamolodchikova   BIOCHEMISTRY-MOSCOW

Influenza and SARS-Coronavirus Activating Proteases TMPRSS2 and HAT Are Expressed at Multiple Sites in Human Respiratory and Gastrointestinal Tracts

(2012) Stephanie Bertram et al.   PLoS One

Characterization of cellular furin content as a potential factor determining the susceptibility of cultured human and animal cells to coronavirus infectious bronchitis virus infection

(2012) Felicia P.L. Tay et al.   VIROLOGY

Mechanisms of Coronavirus Cell Entry Mediated by the Viral Spike Protein

(2012) Sandrine Belouzard et al.   Viruses-Basel

Receptor-bound porcine epidemic diarrhea virus spike protein cleaved by trypsin induces membrane fusion

(2011) Jung-Eun Park et al.   ARCHIVES OF VIROLOGY

Role of host cellular proteases in the pathogenesis of influenza and influenza-induced multiple organ failure

(2011) Hiroshi Kido et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Role of Proteases in the Release of Porcine Epidemic Diarrhea Virus from Infected Cells

(2011) K. Shirato et al.   JOURNAL OF VIROLOGY

Mutations in the spike gene of porcine epidemic diarrhea virus associated with growth adaptation in vitro and attenuation of virulence in vivo

(2011) Tetsuo Sato et al.   VIRUS GENES

Mutation in the cytoplasmic retrieval signal of porcine epidemic diarrhea virus spike (S) protein is responsible for enhanced fusion activity

(2011) Kazuya Shirato et al.   VIRUS RESEARCH

Efficient Activation of the Severe Acute Respiratory Syndrome Coronavirus Spike Protein by the Transmembrane Protease TMPRSS2

(2010) S. Matsuyama et al.   JOURNAL OF VIROLOGY

Type II Transmembrane Serine Proteases

(2009) Thomas H. Bugge et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Two-Step Conformational Changes in a Coronavirus Envelope Glycoprotein Mediated by Receptor Binding and Proteolysis

(2009) S. Matsuyama et al.   JOURNAL OF VIROLOGY

Proteolytic Activation of the Spike Protein at a Novel RRRR/S Motif Is Implicated in Furin-Dependent Entry, Syncytium Formation, and Infectivity of Coronavirus Infectious Bronchitis Virus in Cultured Cells

(2009) Y. Yamada et al.   JOURNAL OF VIROLOGY

Characterization of a Highly Conserved Domain within the Severe Acute Respiratory Syndrome Coronavirus Spike Protein S2 Domain with Characteristics of a Viral Fusion Peptide

(2009) I. G. Madu et al.   JOURNAL OF VIROLOGY

Activation of the SARS coronavirus spike protein via sequential proteolytic cleavage at two distinct sites

(2009) S. Belouzard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structures and Mechanisms of Viral Membrane Fusion Proteins: Multiple Variations on a Common Theme

(2008) Judith M. White et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Entry from the Cell Surface of Severe Acute Respiratory Syndrome Coronavirus with Cleaved S Protein as Revealed by Pseudotype Virus Bearing Cleaved S Protein

(2008) R. Watanabe et al.   JOURNAL OF VIROLOGY

Protease-Mediated Entry via the Endosome of Human Coronavirus 229E

(2008) M. Kawase et al.   JOURNAL OF VIROLOGY

Viral membrane fusion

(2008) Stephen C Harrison   NATURE STRUCTURAL & MOLECULAR BIOLOGY