The Human Alpha Defensin HD5 Neutralizes JC Polyomavirus Infection by Reducing Endoplasmic Reticulum Traffic and Stabilizing the Viral Capsid

Pro-inflammatory and pro-apoptotic properties of Human Defensin 5

(2013) Wuyuan Lu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Progressive Multifocal Leukoencephalopathy-Associated Mutations in the JC Polyomavirus Capsid Disrupt Lactoseries Tetrasaccharide c Binding

(2013) M. S. Maginnis et al.   mBio

Critical Determinants of Human α-Defensin 5 Activity against Non-enveloped Viruses

(2012) Anshu P. Gounder et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional Determinants of Human Enteric α-Defensin HD5

(2012) Mohsen Rajabi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Integrin and Defensin Modulate the Mechanical Properties of Adenovirus

(2012) J. Snijder et al.   JOURNAL OF VIROLOGY

Human Alpha Defensin 5 Expression in the Human Kidney and Urinary Tract

(2012) John David Spencer et al.   PLoS One

The VP1 subunit of JC polyomavirus recapitulates early events in viral trafficking and is a novel tool to study polyomavirus entry

(2012) Christian D.S. Nelson et al.   VIROLOGY

Taxonomical developments in the family Polyomaviridae

(2011) Reimar Johne et al.   ARCHIVES OF VIROLOGY

Role of Endosomes in Simian Virus 40 Entry and Infection

(2011) S. Engel et al.   JOURNAL OF VIROLOGY

BAP31 and BiP are essential for dislocation of SV40 from the endoplasmic reticulum to the cytosol

(2011) Roger Geiger et al.   NATURE CELL BIOLOGY

Molecular mechanism and physiological functions of clathrin-mediated endocytosis

(2011) Harvey T. McMahon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The structure of avian polyomavirus reveals variably sized capsids, non-conserved inter-capsomere interactions, and a possible location of the minor capsid protein VP4

(2011) Peter S. Shen et al.   VIROLOGY

BiP and Multiple DNAJ Molecular Chaperones in the Endoplasmic Reticulum Are Required for Efficient Simian Virus 40 Infection

(2011) E. C. Goodwin et al.   mBio

A Large and Intact Viral Particle Penetrates the Endoplasmic Reticulum Membrane to Reach the Cytosol

(2011) Takamasa Inoue et al.   PLoS Pathogens

Structure-Function Analysis of the Human JC Polyomavirus Establishes the LSTc Pentasaccharide as a Functional Receptor Motif

(2010) Ursula Neu et al.   Cell Host & Microbe

Host defense peptides and their antimicrobial-immunomodulatory duality

(2010) Lars Steinstraesser et al.   IMMUNOBIOLOGY

Human Polyomavirus JC (JCV) Infection of Human B Lymphocytes: A Possible Mechanism for JCV Transmigration across the Blood‐Brain Barrier

(2010) Moti L. Chapagain et al.   JOURNAL OF INFECTIOUS DISEASES

Direct Evidence from Single-Cell Analysis that Human  -Defensins Block Adenovirus Uncoating To Neutralize Infection

(2010) E. K. Nguyen et al.   JOURNAL OF VIROLOGY

Progressive multifocal leukoencephalopathy and other disorders caused by JC virus: clinical features and pathogenesis

(2010) Chen S Tan et al.   LANCET NEUROLOGY

Insight into the Mechanisms of Adenovirus Capsid Disassembly from Studies of Defensin Neutralization

(2010) Jason G. Smith et al.   PLoS Pathogens

Progressive Multifocal Leukoencephalopathy in Patients on Immunomodulatory Therapies

(2009) Eugene O. Major   Annual Review of Medicine

Selective arginines are important for the antibacterial activity and host cell interaction of human α-defensin 5

(2009) Erik de Leeuw et al.   FEBS LETTERS

Calcium Bridge Triggers Capsid Disassembly in the Cell Entry Process of Simian Virus 40

(2009) Masa-aki Kawano et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Defensins in Viral Infections

(2009) Jian Ding et al.   Journal of Innate Immunity

Transcriptional Regulation of BK Virus by Nuclear Factor of Activated T Cells

(2009) J. A. Jordan et al.   JOURNAL OF VIROLOGY

Vesicular Stomatitis Virus Enters Cells through Vesicles Incompletely Coated with Clathrin That Depend upon Actin for Internalization

(2009) David K. Cureton et al.   PLoS Pathogens

Seroepidemiology of Human Polyomaviruses

(2009) Jaime M. Kean et al.   PLoS Pathogens

Mechanism of Adenovirus Neutralization by Human α-Defensins

(2008) Jason G. Smith et al.   Cell Host & Microbe

Human α-Defensins Inhibit BK Virus Infection by Aggregating Virions and Blocking Binding to Host Cells

(2008) Aisling S. Dugan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nuclear factor of activated T-cells (NFAT) plays a role in SV40 infection

(2007) Kate Manley et al.   VIROLOGY