期刊
JOURNAL OF VIROLOGY
卷 87, 期 23, 页码 13059-13062出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/JVI.02380-13
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资金
- National Institutes of Health [R01CA124311, R01CA138268, F30CA177267, P20GM103518]
Comprehensive virome analysis of RNA sequence (RNA-seq) data sets from 118 non-Hodgkin's B-cell lymphomas revealed a small subset that is positive for Epstein-Barr virus (EBV) or human herpesvirus 6B (HHV-6B), with one coinfection. EBV transcriptome analysis revealed expression of the latency genes RPMS1, LMP1, and LMP2, with one sample additionally showing a high level of early lytic expression and another sample showing a high level of EBNA2 expression. HHV-6B transcriptome analysis revealed that the majority of genes were transcribed.
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