Synergistic Effect of the PDZ and p85 -Binding Domains of the NS1 Protein on Virulence of an Avian H5N1 Influenza A Virus

F1Fo-ATPase, F-type proton-translocating ATPase, at the plasma membrane is critical for efficient influenza virus budding

(2012) T. Gorai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Marburg Virus VP35 Can Both Fully Coat the Backbone and Cap the Ends of dsRNA for Interferon Antagonism

(2012) Shridhar Bale et al.   PLoS Pathogens

Evolutionarily conserved bias of amino-acid usage refines the definition of PDZ-binding motif

(2011) Takahiko Chimura et al.   BMC GENOMICS

Phosphatidylinositol-3-kinase (PI3K) is activated by influenza virus vRNA via the pathogen pattern receptor Rig-I to promote efficient type I interferon production

(2011) Eike R. Hrincius et al.   CELLULAR MICROBIOLOGY

Emerging Theme: Cellular PDZ Proteins as Common Targets of Pathogenic Viruses

(2011) R. T. Javier et al.   JOURNAL OF VIROLOGY

The Avian Influenza Virus NS1 ESEV PDZ Binding Motif Associates with Dlg1 and Scribble To Disrupt Cellular Tight Junctions

(2011) L. Golebiewski et al.   JOURNAL OF VIROLOGY

Genome-Wide Analysis of PDZ Domain Binding Reveals Inherent Functional Overlap within the PDZ Interaction Network

(2011) Aartjan J. W. te Velthuis et al.   PLoS One

PDlim2 Selectively Interacts with the PDZ Binding Motif of Highly Pathogenic Avian H5N1 Influenza A Virus NS1

(2011) Jia Yu et al.   PLoS One

The distinct binding properties between avian/human influenza A virus NS1 and Postsynaptic density protein-95 (PSD-95), and inhibition of nitric oxide production

(2011) Heng Zhang et al.   Virology Journal

Analysis of the PDZ binding specificities of Influenza A Virus NS1 proteins

(2011) Miranda Thomas et al.   Virology Journal

Influenza A Virus Polymerase Inhibits Type I Interferon Induction by Binding to Interferon β Promoter Stimulator 1

(2010) Atsushi Iwai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evolution of highly pathogenic avian H5N1 influenza viruses and the emergence of dominant variants

(2010) G. Neumann et al.   JOURNAL OF GENERAL VIROLOGY

Species-Specific Contribution of the Four C-Terminal Amino Acids of Influenza A Virus NS1 Protein to Virulence

(2010) S. M. Soubies et al.   JOURNAL OF VIROLOGY

Virulence Determinants of Avian H5N1 Influenza A Virus in Mammalian and Avian Hosts: Role of the C-Terminal ESEV Motif in the Viral NS1 Protein

(2010) Florian Zielecki et al.   JOURNAL OF VIROLOGY

The ESEV PDZ-Binding Motif of the Avian Influenza A Virus NS1 Protein Protects Infected Cells from Apoptosis by Directly Targeting Scribble

(2010) H. Liu et al.   JOURNAL OF VIROLOGY

Continued Evolution of H5N1 Influenza Viruses in Wild Birds, Domestic Poultry, and Humans in China from 2004 to 2009

(2010) Y. Li et al.   JOURNAL OF VIROLOGY

Structural insights into phosphoinositide 3-kinase activation by the influenza A virus NS1 protein

(2010) B. G. Hale et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A new player in a deadly game: influenza viruses and the PI3K/Akt signalling pathway

(2009) Christina Ehrhardt et al.   CELLULAR MICROBIOLOGY

Interplay between influenza A virus and the innate immune signaling

(2009) Christina Ehrhardt et al.   MICROBES AND INFECTION

Novel Genotypes of H9N2 Influenza A Viruses Isolated from Poultry in Pakistan Containing NS Genes Similar to Highly Pathogenic H7N3 and H5N1 Viruses

(2009) Munir Iqbal et al.   PLoS One

Phylogenetic characterization of H5N1 avian influenza viruses isolated in Indonesia from 2003–2007

(2009) Ryo Takano et al.   VIROLOGY

Loss of function of the influenza A virus NS1 protein promotes apoptosis but this is not due to a failure to activate phosphatidylinositol 3-kinase (PI3K)

(2009) David Jackson et al.   VIROLOGY

Mechanism of Influenza A Virus NS1 Protein Interaction with the p85β, but Not the p85α, Subunit of Phosphatidylinositol 3-Kinase (PI3K) and Up-regulation of PI3K Activity

(2008) Yang Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A new influenza virus virulence determinant: The NS1 protein four C-terminal residues modulate pathogenicity

(2008) D. Jackson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The development and genetic diversity of H5N1 influenza virus in China, 1996–2006

(2008) L. Duan et al.   VIROLOGY

A Specificity Map for the PDZ Domain Family

(2008) Raffi Tonikian et al.   PLOS BIOLOGY

Evolutionary Dynamics and Emergence of Panzootic H5N1 Influenza Viruses

(2008) Dhanasekaran Vijaykrishna et al.   PLoS Pathogens