Article
Microbiology
Yuan Yuan, Yara Seif, Kevin Rychel, Reo Yoo, Siddharth Chauhan, Saugat Poudel, Tahani Al-bulushi, Bernhard O. Palsson, Anand Sastry
Summary: By combining pan-genome and transcriptomic analytics, variations in transcriptional regulatory networks across six strains of Salmonella enterica serovar Typhimurium were revealed.
Article
Gastroenterology & Hepatology
Nirmal Kumar Mohakud, Rakesh Kumar Panda, Saumya Darshana Patra, Bikash Ranjan Sahu, Mrinmoy Ghosh, Gajraj Singh Kushwaha, Namrata Misra, Mrutyunjay Suar
Summary: The study analyzed a strain of Salmonella isolated from a patient with gastroenteritis in Odisha, India, revealing highly conserved genes related to drug resistance and virulence, suggesting the potential dissemination of a novel multi-drug resistant strain with enhanced virulence.
Article
Virology
Cedric Woudstra, Sophie A. Granier
Summary: This study investigates the anti-phage defenses in Salmonella Typhimurium using bioinformatics and identifies nucleic acid degradation and abortive infection mechanisms. Mobile genetic elements containing anti-phage systems were also found in Salmonella and the Enterobacteriaceae family. This research provides insights for designing preventive measures against the spread of phage resistance.
Article
Veterinary Sciences
Joerg Linde, Istvan Szabo, Simon H. Tausch, Carlus Deneke, Ulrich Methner
Summary: Salmonella enterica subspecies enterica serovar Dublin (S. Dublin) is a highly pathogenic serovar causing enteritis and/or systemic diseases in cattle. It has the potential to cause severe infections in humans. This study used whole-genome sequencing to evaluate the genetic relationship between S. Dublin strains from cattle and food sources, and found a high genetic correlation between the two, highlighting the potential for human infections.
FRONTIERS IN VETERINARY SCIENCE
(2023)
Article
Microbiology
Lester Hiley, Rikki M. A. Graham, Amy V. Jennison
Summary: This study identified two genes possibly associated with change of phage type in IncI1 plasmids. IncI1 plasmids were classified as either 'Delta' or 'Col' plasmids, and genetic recombination leading to a switch between Delta and Col gene sets was observed at the rfsF site. Widespread distribution of these plasmids with extensive regions showing high sequence identity was also indicated.
Article
Food Science & Technology
Rui Dong, Xiaojie Qin, Shoukui He, Xiujuan Zhou, Yan Cui, Chunlei Shi, Yiping He, Xianming Shi
Summary: The study revealed that DsrA plays a crucial role in promoting oxidative stress resistance in S. Typhimurium by regulating the expression of antioxidant enzymes and maintaining intracellular redox balance.
Article
Microbiology
Jialiang Xu, Jia Li, Yi Yan, Pengjun Han, Yigang Tong, Xu Li
Summary: A lytic phage SW16-7 was isolated from medical sewage, showing high infectivity against Salmonella enterica serovar Weltevreden and other strains. In vitro inhibition assays demonstrated its effective antibacterial effect for up to 12 h. The phage's genome lacks virulence factors and antibiotic resistance genes, suggesting its potential as a biocontrol agent against S. Weltevreden.
Article
Microbiology
Somaieh Sabzali, Majid Bouzari
Summary: Salmonellosis is a significant global foodborne disease, with multidrug-resistant Salmonella spp. becoming a worldwide problem. This study isolated and characterized bacteriophages specific to Salmonella Paratyphi B and S. Typhimurium, with a focus on antibiotic resistance and ESBL gene prevalence. The isolated phages show potential for controlling food contamination and phage therapy for infected animals.
FEMS MICROBIOLOGY LETTERS
(2021)
Article
Gastroenterology & Hepatology
Meiying Yan, Yongming Zhou, Yang Cao, Zhenpeng Li, Xin Lu, Bo Pang, Shukun Wang, Biao Kan
Summary: This study discovered a new serovar of Salmonella (S. enterica subsp. II serovar 4,5,12:a:-) and demonstrated its ability to infect humans and cause clusters of cases. Whole-genome sequencing detection and surveillance of Salmonella can accurately define Salmonella classification and clonality, improve diagnosis, facilitate outbreak detection, and aid in the source tracing of salmonellosis epidemics.
Article
Microbiology
Lauren K. K. Hudson, William E. E. Andershock, Xiaorong Qian, Paula L. L. Gibbs, Kelly Orejuela, Katie N. N. Garman, John R. R. Dunn, Thomas G. G. Denes
Summary: This study evaluated the clinical and epidemiological significance of Salmonella enterica subsp. enterica serovar Newport. The results showed that Newport serovar is the second most prevalent clinically isolated Salmonella serovar in the United States and can contaminate various food products. The study also identified 18 potential epidemiological clusters and highlighted the importance of this research for public health surveillance and the Salmonella research community.
MICROBIOLOGY SPECTRUM
(2023)
Article
Biotechnology & Applied Microbiology
Yaming Hong, Ruoyun Ji, Zhenyu Wang, Jiaojie Gu, Xinan Jiao, Qiuchun Li
Summary: A novel multiplex PCR method was established to rapidly and accurately detect and differentiate Salmonella enterica serovar Typhimurium monophasic variants and S. Typhimurium. The method has a detection limit for DNA concentration at 10 pg/μL and successfully differentiated isolates from laboratory preservation and pig farm samples.
Article
Microbiology
Yu Han, Yu Li, Zhiwei Zeng, Wenjing Li, Saixiang Feng, Weisheng Cao
Summary: This study explores the resistance mechanism and activity of the antimicrobial peptide MccY against Salmonella strains. The deletion of Ton system genes resulted in resistance to MccY and mutants showed increased susceptibility to MccY under a low-iron condition. MccY may decrease the virulence of S. Typhimurium by altering multiple physiological properties.
MICROBIOLOGY SPECTRUM
(2022)
Article
Biochemistry & Molecular Biology
Seok Hywan Hyeon, Woon Ki Lim, Hae Ja Shin
Summary: A novel biosensor utilizing full-length Det7 phage tail protein on gold-coated surfaces was developed for rapid and selective detection of S. Typhimurium. The sensor showed high specificity in recognizing S. Typhimurium, allowing for potential applications in early disease prevention and health monitoring.
BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY
(2021)
Article
Microbiology
Sebastian Braetz, Peter Schwerk, Nara Figueroa-Bossi, Karsten Tedin, Marcus Fulde
Summary: Our study demonstrates that prophages significantly reduce persister cell formation in lysogenic cells exposed to DNA-gyrase-targeting drugs, and also impact the initial drug susceptibility.
MICROBIOLOGY SPECTRUM
(2023)
Article
Chemistry, Analytical
Han Du, Xu Zhang, Mingru Yao, Qingli Yang, Wei Wu
Summary: This study successfully constructed aptamer-guided luminous microspheres using carbon dots fluorescence, which can efficiently recognize and detect Salmonella enterica serovar Typhimurium. The method shows high sensitivity and has broad application prospects.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Multidisciplinary Sciences
Minsik Kim, Hee Jung Kim, Sang Hyeon Son, Hye Jin Yoon, Youngbin Lim, Jong Woo Lee, Yeong-Jae Seok, Kyeong Sik Jin, Yeon Gyu Yu, Seong Keun Kim, Sangryeol Ryu, Hyung Ho Lee
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2016)
Article
Biotechnology & Applied Microbiology
Yoonjee Chang, Minsik Kim, Sangryeol Ryu
Article
Food Science & Technology
Jinwoo Kim, Minsik Kim, Seongmi Kim, Sangryeol Ryu
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY
(2017)
Article
Cell Biology
Troy P. Hubbard, Gabriel Billings, Tobias Doerr, Brandon Sit, Alyson R. Warr, Carole J. Kuehl, Minsik Kim, Fernanda Delgado, John J. Mekalanos, Joseph A. Lewnard, Matthew K. Waldor
SCIENCE TRANSLATIONAL MEDICINE
(2018)
Article
Chemistry, Analytical
Seongmi Kim, Minsik Kim, Sangryeol Ryu
ANALYTICAL CHEMISTRY
(2014)
Article
Biotechnology & Applied Microbiology
Minsik Kim, Sujin Kim, Bookyung Park, Sangryeol Ryu
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
(2014)
Article
Virology
Minsik Kim, Sunggi Heu, Sangryeol Ryu
ARCHIVES OF VIROLOGY
(2014)
Article
Microbiology
Hyeongsoon Kim, Minsik Kim, Jaewoo Bai, Jeong-A Lim, Sunggi Heu, Sangryeol Ryu
FRONTIERS IN MICROBIOLOGY
(2019)
Article
Virology
Eunsu Ha, Jihwan Chun, Minsik Kim, Sangryeol Ryu
Article
Food Science & Technology
Haejoon Park, Jinwoo Kim, Minsik Kim, Yerin Park, Sangryeol Ryu
Summary: The study proposes a novel strategy combining thermostable bacteriophages with thermal processing of food production plants to control foodborne pathogens and bacterial contamination. By optimizing bacteriophage cocktail components and verifying the antibacterial strategy in model systems, it was found that thermostable phages significantly reduced the number of post-contaminated Salmonella.
FOOD RESEARCH INTERNATIONAL
(2021)
Article
Food Science & Technology
Hwa Jeong You, Jung Hyen Lee, Minjin Oh, Sin Young Hong, Doyeon Kim, Jieun Noh, Minsik Kim, Byoung Sik Kim
Summary: V. parahaemolyticus is a major pathogen causing seafood-borne illness, while VPT02 may serve as a sustainable treatment against V. parahaemolyticus with strong bacteriolytic activity.
FOOD RESEARCH INTERNATIONAL
(2021)
Article
Multidisciplinary Sciences
Hyo Ju Choi, Minsik Kim
Summary: This study introduced random mutations into a staphylococcal temperate Siphoviridae phage SA3821 using a chelating agent, resulting in a mutant phage with increased bactericidal activity and thermostability. Mutations were mainly concentrated in genes related to the phage tail module, potentially responsible for the altered traits.
SCIENTIFIC REPORTS
(2021)
Article
Biotechnology & Applied Microbiology
Hyeongsoon Kim, Minsik Kim, Sam-Nyu Jee, Sunggi Heu, Sangryeol Ryu
Summary: Pectobacterium carotovorum subsp. carotovorum is a pathogen that causes soft rot disease in crops by producing plant cell wall-degrading enzymes (PCWDEs). The emergence of antibiotic-resistant bacteria and the demand for harmless antimicrobial products have driven the search for alternative therapeutic strategies. In this study, a phage cocktail targeting two different phage receptors was developed to control P. carotovorum subsp. carotovorum. The phage cocktail effectively reduced the populations of P. carotovorum subsp. carotovorum and attenuated its virulence, as demonstrated by decreased PCWDE production and decreased swimming motility in phage-resistant mutants. These results suggest that phage cocktails targeting multiple receptors could be an effective approach for controlling P. carotovorum subsp. carotovorum in crops.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
(2022)
Article
Food Science & Technology
Jieon Lee, Doyeon Kim, Minsik Kim
Summary: Bacteriophages are being reconsidered as a potential alternative to control bacterial pathogens in the food industry. By implementing an adaptive laboratory evolution approach, the heat stability of a newly isolated Salmonella-infecting phage was improved and demonstrated its efficacy in the poultry scalding process.
FOOD RESEARCH INTERNATIONAL
(2023)
Article
Food Science & Technology
Doyeon Kim, Minsik Kim
Summary: In this study, we developed a bioluminescent reporter bacteriophage for rapid and specific detection of Cronobacter sakazakii (Cs) in food and food processing environments.
FOOD RESEARCH INTERNATIONAL
(2023)
