Hepatitis C Virus Activates the mTOR/S6K1 Signaling Pathway in Inhibiting IRS-1 Function for Insulin Resistance

Hepatitis C Virus Infection Promotes Hepatic Gluconeogenesis through an NS5A-Mediated, FoxO1-Dependent Pathway

(2011) L. Deng et al.   JOURNAL OF VIROLOGY

PIK3CA and KRAS mutations predict for response to everolimus therapy: now that’s RAD001

(2010) Morassa Mohseni et al.   JOURNAL OF CLINICAL INVESTIGATION

Hepatitis C Virus Differentially Modulates Activation of Forkhead Transcription Factors and Insulin-Induced Metabolic Gene Expression

(2010) A. Banerjee et al.   JOURNAL OF VIROLOGY

Activation of mTORC1 in two steps: Rheb-GTP activation of catalytic function and increased binding of substrates to raptor1

(2009) Joseph Avruch et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

HCV replication suppresses cellular glucose uptake through down-regulation of cell surface expression of glucose transporters

(2009) Daisuke Kasai et al.   JOURNAL OF HEPATOLOGY

How Insulin Receptor Substrate Proteins Regulate the Metabolic Capacity of the Liver - Implications for Health and Disease

(2008) Louise Fritsche et al.   CURRENT MEDICINAL CHEMISTRY

S6K Directly Phosphorylates IRS-1 on Ser-270 to Promote Insulin Resistance in Response to TNF-α Signaling through IKK2

(2008) Jin Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insulin Resistance in Chronic Hepatitis C: Association With Genotypes 1 and 4, Serum HCV RNA Level, and Liver Fibrosis

(2007) Rami Moucari et al.   GASTROENTEROLOGY