Unstable Polymerase-Nucleoprotein Interaction Is Not Responsible for Avian Influenza Virus Polymerase Restriction in Human Cells

Investigation of Influenza Virus Polymerase Activity in Pig Cells

(2012) O. Moncorge et al.   JOURNAL OF VIROLOGY

Influenza Polymerase Activity Correlates with the Strength of Interaction between Nucleoprotein and PB2 through the Host-Specific Residue K/E627

(2012) Andy Ka-Leung Ng et al.   PLoS One

Adaptive mutations in NEP compensate for defective H5N1 RNA replication in cultured human cells

(2012) Benjamin Mänz et al.   Nature Communications

Influence of PB2 host-range determinants on the intranuclear mobility of the influenza A virus polymerase

(2011) A. Foeglein et al.   JOURNAL OF GENERAL VIROLOGY

PA Residues in the 2009 H1N1 Pandemic Influenza Virus Enhance Avian Influenza Virus Polymerase Activity in Mammalian Cells

(2011) K. A. Bussey et al.   JOURNAL OF VIROLOGY

Host- and Strain-Specific Regulation of Influenza Virus Polymerase Activity by Interacting Cellular Proteins

(2011) E. Bortz et al.   mBio

PB2 Residue 271 Plays a Key Role in Enhanced Polymerase Activity of Influenza A Viruses in Mammalian Host Cells

(2010) K. A. Bussey et al.   JOURNAL OF VIROLOGY

Adaptation of Pandemic H1N1 Influenza Viruses in Mice

(2010) N. A. Ilyushina et al.   JOURNAL OF VIROLOGY

PB2 Residue 158 Is a Pathogenic Determinant of Pandemic H1N1 and H5 Influenza A Viruses in Mice

(2010) B. Zhou et al.   JOURNAL OF VIROLOGY

Evidence for Avian and Human Host Cell Factors That Affect the Activity of Influenza Virus Polymerase

(2010) O. Moncorge et al.   JOURNAL OF VIROLOGY

Biological and Structural Characterization of a Host-Adapting Amino Acid in Influenza Virus

(2010) Shinya Yamada et al.   PLoS Pathogens

Adaptive strategies of the influenza virus polymerase for replication in humans

(2009) Andrew Mehle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single mutation at the amino acid position 627 of PB2 that leads to increased virulence of an H5N1 avian influenza virus during adaptation in mice can be compensated by multiple mutations at other sites of PB2

(2009) Junwei Li et al.   VIRUS RESEARCH

Identifying Changes in Selective Constraints: Host Shifts in Influenza

(2009) Asif U. Tamuri et al.   PLoS Computational Biology

Host Restriction of Avian Influenza Viruses at the Level of the Ribonucleoproteins

(2008) Nadia Naffakh et al.   Annual Review of Microbiology

Comprehensive analysis of circadian periodic pattern in plant transcriptome

(2008) Andrey Ptitsyn   BMC BIOINFORMATICS

An Inhibitory Activity in Human Cells Restricts the Function of an Avian-like Influenza Virus Polymerase

(2008) Andrew Mehle et al.   Cell Host & Microbe

Avian Influenza A Virus Polymerase Association with Nucleoprotein, but Not Polymerase Assembly, Is Impaired in Human Cells during the Course of Infection

(2008) M.-A. Rameix-Welti et al.   JOURNAL OF VIROLOGY

The structural basis for an essential subunit interaction in influenza virus RNA polymerase

(2008) Eiji Obayashi et al.   NATURE

Interaction of Polymerase Subunit PB2 and NP with Importin α1 Is a Determinant of Host Range of Influenza A Virus

(2008) Gülsah Gabriel et al.   PLoS Pathogens