A Panel of IgG1 b12 Variants with Selectively Diminished or Enhanced Affinity for Fc  Receptors To Define the Role of Effector Functions in Protection against HIV

A dimeric form of the HIV-1 antibody 2G12 elicits potent antibody-dependent cellular cytotoxicity

(2010) Joshua S Klein et al.   AIDS

Therapeutic Antibodies in HIV Treatment - Classical Approaches to Novel Advances

(2010) Irene A. Abela et al.   CURRENT PHARMACEUTICAL DESIGN

A robust, high-throughput assay to determine the phagocytic activity of clinical antibody samples

(2010) Margaret E. Ackerman et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Fc-Glycosylation Influences Fc  Receptor Binding and Cell-Mediated Anti-HIV Activity of Monoclonal Antibody 2G12

(2010) D. N. Forthal et al.   JOURNAL OF IMMUNOLOGY

HIV-1 Replication in Langerhans and Interstitial Dendritic Cells Is Inhibited by Neutralizing and Fc-Mediated Inhibitory Antibodies

(2010) M. Peressin et al.   JOURNAL OF VIROLOGY

In-Solution Virus Capture Assay Helps Deconstruct Heterogeneous Antibody Recognition of Human Immunodeficiency Virus Type 1

(2010) D. P. Leaman et al.   JOURNAL OF VIROLOGY

Antibodies to watch in 2010

(2010) Janice M. Reichert   mAbs

CD19 targeting of chronic lymphocytic leukemia with a novel Fc-domain-engineered monoclonal antibody

(2009) F. T. Awan et al.   BLOOD

A nonfucosylated human antibody to CD19 with potent B-cell depletive activity for therapy of B-cell malignancies

(2009) Pina M. Cardarelli et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Utilization of Immunoglobulin G Fc Receptors by Human Immunodeficiency Virus Type 1: a Specific Role for Antibodies against the Membrane-Proximal External Region of gp41

(2009) L. G. Perez et al.   JOURNAL OF VIROLOGY

Effective, low-titer antibody protection against low-dose repeated mucosal SHIV challenge in macaques

(2009) Ann J Hessell et al.   NATURE MEDICINE

Glycosylation as a strategy to improve antibody-based therapeutics

(2009) Roy Jefferis   NATURE REVIEWS DRUG DISCOVERY

Vaccination with ALVAC and AIDSVAX to Prevent HIV-1 Infection in Thailand

(2009) Supachai Rerks-Ngarm et al.   NEW ENGLAND JOURNAL OF MEDICINE

Fc receptor-mediated antiviral antibodies

(2009) Donald N Forthal et al.   Current Opinion in HIV and AIDS

The Cat and Mouse of HIV-1 Antibody Escape

(2009) John R. Mascola   PLoS Pathogens

Broadly Neutralizing Human Anti-HIV Antibody 2G12 Is Effective in Protection against Mucosal SHIV Challenge Even at Low Serum Neutralizing Titers

(2009) Ann J. Hessell et al.   PLoS Pathogens

Optimization of antibody binding to Fc RIIa enhances macrophage phagocytosis of tumor cells

(2008) J. O. Richards et al.   MOLECULAR CANCER THERAPEUTICS