Differential Sensitivities of Retroviruses to Integrase Strand Transfer Inhibitors

Identification and Characterization of Persistent Intracellular Human Immunodeficiency Virus Type 1 Integrase Strand Transfer Inhibitor Activity

(2010) Yasuhiro Koh et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Biochemical and Pharmacological Analyses of HIV-1 Integrase Flexible Loop Mutants Resistant to Raltegravir

(2010) Mathieu Métifiot et al.   BIOCHEMISTRY

Inhibition of Xenotropic Murine Leukemia Virus-Related Virus by APOBEC3 Proteins and Antiviral Drugs

(2010) T. Paprotka et al.   JOURNAL OF VIROLOGY

Retroviral intasome assembly and inhibition of DNA strand transfer

(2010) Stephen Hare et al.   NATURE

Raltegravir Is a Potent Inhibitor of XMRV, a Virus Implicated in Prostate Cancer and Chronic Fatigue Syndrome

(2010) Ila R. Singh et al.   PLoS One

Structure-based modeling of the functional HIV-1 intasome and its inhibition

(2010) L. Krishnan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular mechanisms of retroviral integrase inhibition and the evolution of viral resistance

(2010) S. Hare et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Response of a simian immunodeficiency virus (SIVmac251) to raltegravir: a basis for a new treatment for simian AIDS and an animal model for studying lentiviral persistence during antiretroviral therapy

(2010) Mark G Lewis et al.   Retrovirology

Susceptibility of the human retrovirus XMRV to antiretroviral inhibitors

(2010) Robert A Smith et al.   Retrovirology

Resistance to Integrase Inhibitors

(2010) Mathieu Métifiot et al.   Viruses-Basel

Strand transfer inhibitors of HIV-1 integrase: Bringing IN a new era of antiretroviral therapy

(2009) Damian J. McColl et al.   ANTIVIRAL RESEARCH

Molecular Architecture of the Mos1 Paired-End Complex: The Structural Basis of DNA Transposition in a Eukaryote

(2009) Julia M. Richardson et al.   CELL

Transgenesis inXenopususing theSleeping Beautytransposon system

(2009) Donald A. Yergeau et al.   DEVELOPMENTAL DYNAMICS

Retroviral integrase superfamily: the structural perspective

(2009) Marcin Nowotny   EMBO REPORTS

Loss of Raltegravir Susceptibility by Human Immunodeficiency Virus Type 1 Is Conferred via Multiple Nonoverlapping Genetic Pathways

(2009) S. Fransen et al.   JOURNAL OF VIROLOGY

The Requirement for Cellular Transportin 3 (TNPO3 or TRN-SR2) during Infection Maps to Human Immunodeficiency Virus Type 1 Capsid and Not Integrase

(2009) L. Krishnan et al.   JOURNAL OF VIROLOGY

Efficient stable gene transfer into human cells by the Sleeping Beauty transposon vectors

(2009) Z IZSVAK   METHODS

First Mariner Mos1 Transposase Inhibitors (Supplementary Data)

(2009) N. Bouchet et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Molecular evolution of a novel hyperactive Sleeping Beauty transposase enables robust stable gene transfer in vertebrates

(2009) Lajos Mátés et al.   NATURE GENETICS

Early onset of autoimmune disease by the retroviral integrase inhibitor raltegravir

(2009) G. B. Beck-Engeser et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The SET Complex Acts as a Barrier to Autointegration of HIV-1

(2009) Nan Yan et al.   PLoS Pathogens

Selection of diverse and clinically relevant integrase inhibitor-resistant human immunodeficiency virus type 1 mutants

(2008) M KOBAYASHI et al.   ANTIVIRAL RESEARCH

Trex1 Prevents Cell-Intrinsic Initiation of Autoimmunity

(2008) Daniel B. Stetson et al.   CELL

HIV-2 integrase gene polymorphism and phenotypic susceptibility of HIV-2 clinical isolates to the integrase inhibitors raltegravir and elvitegravir in vitro

(2008) B. Roquebert et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Discovery of Raltegravir, a Potent, Selective Orally Bioavailable HIV-Integrase Inhibitor for the Treatment of HIV-AIDS Infection

(2008) Vincenzo Summa et al.   JOURNAL OF MEDICINAL CHEMISTRY

Subgroup and Resistance Analyses of Raltegravir for Resistant HIV-1 Infection

(2008) David A. Cooper et al.   NEW ENGLAND JOURNAL OF MEDICINE

Functional and structural characterization of the integrase from the prototype foamy virus

(2008) Eugene Valkov et al.   NUCLEIC ACIDS RESEARCH