期刊
JOURNAL OF VIROLOGY
卷 84, 期 8, 页码 4095-4099出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/JVI.02631-09
关键词
-
类别
资金
- National Institutes of Health [AI 063987, AI 076094, AI 06354]
- International AIDS Vaccine Initiative
- late William F. McCarty-Cooper
Foamy virus evolution closely parallels that of the host species, indicating virus-host coadaptation. We studied simian foamy viruses (SFVs) from common marmosets, spider monkeys, and squirrel monkeys, New World monkey (NWM) species that share geographic ranges. The TRIM5 alpha protein from each of these NWM species inhibited the replication of at least one of the SFVs associated with the other two species but did not affect the replication of its own SFV. Thus, TRIM5 alpha has potentially shaped the evolution of SFVs in NWM hosts. Conversely, SFVs may have influenced the evolution of TRIM5 variants in New World primates.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据