Bypass of genetic constraints during mutator evolution to antibiotic resistance

Empirical fitness landscapes and the predictability of evolution

(2014) J. Arjan G.M. de Visser et al.   NATURE REVIEWS GENETICS

Resistance to β-Lactam Antibiotics Conferred by Point Mutations in Penicillin-Binding Proteins PBP3, PBP4 and PBP6 in Salmonella enterica

(2014) Song Sun et al.   PLoS One

EPISTATIC INTERACTIONS DETERMINE THE MUTATIONAL PATHWAYS AND COEXISTENCE OF LINEAGES IN CLONALESCHERICHIA COLIPOPULATIONS

(2013) Ram Prasad Maharjan et al.   EVOLUTION

Patterns of Epistasis between Beneficial Mutations in an Antibiotic Resistance Gene

(2013) Martijn F. Schenk et al.   MOLECULAR BIOLOGY AND EVOLUTION

Mutational Spectrum Drives the Rise of Mutator Bacteria

(2013) Alejandro Couce et al.   PLoS Genetics

Magnitude and sign epistasis among deleterious mutations in a positive-sense plant RNA virus

(2012) J Lalić et al.   HEREDITY

Evolution in Fast Forward: a Potential Role for Mutators in Accelerating Staphylococcus aureus Pathoadaptation

(2012) G. S. Canfield et al.   JOURNAL OF BACTERIOLOGY

Evolutionary insight from whole-genome sequencing of experimentally evolved microbes

(2012) JEREMY R. DETTMAN et al.   MOLECULAR ECOLOGY

General and inducible hypermutation facilitate parallel adaptation in Pseudomonas aeruginosa despite divergent mutation spectra

(2012) M. R. Weigand et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Molecular Diversity of Adaptive Convergence

(2012) O. Tenaillon et al.   SCIENCE

Quantifying the Adaptive Potential of an Antibiotic Resistance Enzyme

(2012) Martijn F. Schenk et al.   PLoS Genetics

Genomics of Adaptation during Experimental Evolution of the Opportunistic Pathogen Pseudomonas aeruginosa

(2012) Alex Wong et al.   PLoS Genetics

Methicillin Resistance Alters the Biofilm Phenotype and Attenuates Virulence in Staphylococcus aureus Device-Associated Infections

(2012) Clarissa Pozzi et al.   PLoS Pathogens

Insights Into Mutagenesis UsingEscherichia coliChromosomallacZStrains That Enable Detection of a Wide Spectrum of Mutational Events

(2011) Tracey Seier et al.   GENETICS

Evolutionary paths to antibiotic resistance under dynamically sustained drug selection

(2011) Erdal Toprak et al.   NATURE GENETICS

The causes of epistasis

(2011) J. A. G. M. de Visser et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Evolutionary Accessibility of Mutational Pathways

(2011) Jasper Franke et al.   PLoS Computational Biology

Reciprocal Sign Epistasis between Frequently Experimentally Evolved Adaptive Mutations Causes a Rugged Fitness Landscape

(2011) Daniel J. Kvitek et al.   PLoS Genetics

Initial Mutations Direct Alternative Pathways of Protein Evolution

(2011) Merijn L. M. Salverda et al.   PLoS Genetics

Hypermutability and Compensatory Adaptation in Antibiotic‐Resistant Bacteria

(2010) Gabriel G. Perron et al.   AMERICAN NATURALIST

Frequency of Spontaneous Resistance to Fosfomycin Combined with Different Antibiotics in Pseudomonas aeruginosa

(2010) A. Rodriguez-Rojas et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Fitness Epistasis and Constraints on Adaptation in a Human Immunodeficiency Virus Type 1 Protein Region

(2010) J. da Silva et al.   GENETICS

Reciprocal sign epistasis is a necessary condition for multi-peaked fitness landscapes

(2010) Frank J. Poelwijk et al.   JOURNAL OF THEORETICAL BIOLOGY

Membrane Permeability and Regulation of Drug “Influx and Efflux” in Enterobacterial Pathogens

(2008) Anne Davin-Regli et al.   CURRENT DRUG TARGETS

Evidence for recombination among the alleles encoding TEM and SHV  -lactamases

(2008) M. Barlow et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

An amino acid substitution in PBP-3 in Haemophilus influenzae associate with the invasion to bronchial epithelial cells

(2008) Tadashi Okabe et al.   MICROBIOLOGICAL RESEARCH