Article
Surgery
Daniel Castaneda, Francisco Franco Azar, Ishtiaq Hussain, Badar Hasan, Roger Charles, Ronnie Pimentel, Fernando J. Castro
Summary: Post-RYGB anastomotic strictures can be successfully treated with hydrostatic balloon dilation, but patients with delayed dilations and pre-existing nausea/vomiting have an increased risk of dilation failure and need for further interventions.
Article
Surgery
Robert Cubas, Robert Andres, Shravan Chintalapani, Estefania Roldan, Andrea Marcadis, Valerie Wu Chao Ying, Robert Bowles, Jose Martinez
Summary: The study reviewed one surgeon's experience with esophageal dilations after transhiatal esophagectomy, showing that early aggressive endoscopic management of esophageal anastomotic strictures after THE can be safely performed.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2021)
Article
Gastroenterology & Hepatology
Yuhei Iwasa, Takuji Iwashita, Keisuke Iwata, Shinya Uemura, Mitsuru Okuno, Ryuichi Tezuka, Akihiko Senju, Tsuyoshi Mukai, Masahito Shimizu
Summary: This study retrospectively analyzed 40 patients with benign choledochojejunal anastomotic stricture (CJS) who were treated with balloon dilation and balloon endoscopy-assisted endoscopic retrograde cholangiopancreatography (BE-ERCP). The results showed that the technical and clinical success rates were 93% and 100% respectively, and the recurrence rate of CJS was 32%. Early occurrence of CJS after surgery and residual waist circumference during balloon dilation were identified as significant risk factors for recurrence.
BMC GASTROENTEROLOGY
(2023)
Article
Medicine, General & Internal
Lauren A. Beeder, Grayden S. Cook, Samantha W. Nealon, Shervin Badkhshan, Sarah C. Sanders, Dylan P. Perito, Steven J. Hudak, Allen F. Morey
Summary: Transurethral balloon dilation is a minimally invasive treatment for urethral stricture disease. The use of non-medicated balloons resulted in a recurrence rate of approximately 50%, regardless of previous treatments, radiation history, or stricture characteristics.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Gastroenterology & Hepatology
Takeshi Tomoda, Hironari Kato, Toru Ueki, Tsuneyoshi Ogawa, Ken Hirao, Yutaka Akimoto, Kazuyuki Matsumoto, Shigeru Horiguchi, Koichiro Tsutsumi, Hiroyuki Okada
Summary: Endoscopic balloon dilatation combined with plastic stent deployment for 6 months is a safe and effective strategy for HJAS, achieving a high resolution rate for strictures with low incidence of adverse events.
DIGESTIVE ENDOSCOPY
(2022)
Article
Surgery
Brett Hoskins, Erik Almazan, Brenna Hohl, Kenneth Ng
Summary: This study compared procedure time, fluoroscopy time, and safety profile of esophageal dilation using either EsoFLIP or E + CRE in children. The results showed that EsoFLIP had shorter median procedure and fluoroscopy times compared to E + CRE. There were no complications or unplanned hospitalizations in either group, indicating that EsoFLIP was faster, required less fluoroscopy, and was equally safe.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Article
Medicine, General & Internal
Xin Miao, Li Liu, Xiang Wang, Zhining Fan, Lin Miao, Jiankun Wang
Summary: This study investigated the feasibility of endoscopic dilation combined with bleomycin injection for benign anastomotic stricture after rectal surgery. The results showed that compared to simple endoscopic dilation, endoscopic dilation combined with bleomycin injection may reduce the treatment times and prolong the reintervention interval. This is a safe and effective treatment method.
Article
Gastroenterology & Hepatology
Gyu Young Pih, Do Hoon Kim, Hee Kyong Na, Ji Yong Ahn, Jeong Hoon Lee, Kee Wook Jung, Kee Don Choi, Ho June Song, Gin Hyug Lee, Hwoon-Yong Jung
Summary: Through reviewing the medical records of patients who underwent primary treatment for esophagojejunostomy anastomotic stricture after a total gastrectomy between 2010 and 2018, we found that endoscopic incisional therapy (EIT) is a safe and effective treatment modality compared with balloon dilatation, showing a significantly lower re-stricture rate.
JOURNAL OF GASTROINTESTINAL SURGERY
(2021)
Article
Medicine, General & Internal
Bing Wang, Wenzhi Gao, Kunlin Yang, Honglei Liu, Yangjun Han, Mingxin Diao, Chao Zuo, Minghua Zhang, Yingzhi Diao, Zhihua Li, Xinfei Li, Gang Wang, Peng Zhang, Chunji Wang, Chunjuan Xiao, Chen Huang, Yaming Gu, Xuesong Li
Summary: This study aimed to investigate the efficacy of balloon dilation in ureteral stricture and analyze the risk factors for its failure. A retrospective analysis of 196 patients who underwent balloon dilation was conducted, with 127 patients having complete data. The success rates of balloon dilation and balloon dilation combined with endoureterotomy for lower ureteral stricture were higher compared to other cases. Balloon circumference and multiple ureteral strictures were identified as risk factors for balloon dilation failure.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Urology & Nephrology
Dong Zi, Wentao Cao, Fang Chen, Liang Zhu
Summary: The purpose of the research is to compare the safety and efficacy differences of robot-assisted laparoscopy (RALP), conventional laparoscopy (LP), and balloon dilation (BD) in treating benign ureteral stricture (BUS). The results showed that RALP, LP, and BD have similar short-term outcomes and complication rates, while BD has a poorer long-term success rate compared to RALP and LP.
JOURNAL OF ENDOUROLOGY
(2023)
Article
Gastroenterology & Hepatology
Oliver Cronin, Sunil Gupta, Julia Gauci, Anthony Whitfield, Timothy O'Sullivan, Muhammad Abuarisha, Hunter Wang, Eric Yong Tat Lee, Stephen J. Williams, Nicholas Graeme Burgess, Michael J. Bourke
Summary: Large adenomatous anastomotic polyps (LAAPs) represent a rare condition with limited data on prevalence and characteristics. This study demonstrated that LAAPs can be safely and effectively managed through endoscopic resection without recurrence at follow-up.
Article
Surgery
Naresh Sundaresan, B. Amy Hiticas, Mariel Sullivan, Benedict Y. Hui, Lauren Poliakin, Kyle J. Thompson, Iain H. McKillop, Selwan Barbat, Timothy S. Kuwada, Keith S. Gersin, Abdelrahman Nimeri
Summary: The method of anastomosis for creating the gastrojejunal anastomosis (GJA) may impact the formation of strictures.
Article
Medicine, General & Internal
Yonghua Bi, Jianzhuang Ren, Xinwei Han
Summary: This study reported the long-term outcomes of large balloon dilation for benign anastomotic strictures following esophagectomy for esophageal cancer. The results showed that large balloon dilation had a high clinical success rate, a low perforation rate, and significantly improved dysphagia symptoms in patients.
Article
Medicine, Research & Experimental
Anthony Howard, Seilesh Babu, Michael Haupert, Prasad John Thottam
Summary: This study aimed to demonstrate the safety and limited complications of balloon eustachian tuboplasty (BET) in pediatric patients. A retrospective chart review of 43 encounters found a 4.7% complication rate, mainly consisting of epistaxis and vertigo. The average age of patients evaluated was 12.4 years old with a range of 6.6 to 17.7 years old.
Article
Gastroenterology & Hepatology
Dezheng Lin, Wei Liu, Zexian Chen, Xiaowen He, Zheyu Zheng, Ping Lan, Jiancong Hu
Summary: Endoscopic stricturotomy is a safe and effective technique for the treatment of postoperative benign anastomotic stricture. However, if the length of the stricture is equal to or greater than 1 cm, endoscopic stricturotomy may not be effective, and recurrence of postoperative benign anastomotic stricture is likely.
DISEASES OF THE COLON & RECTUM
(2022)
Article
Chemistry, Multidisciplinary
Yehree Kim, Woo Seok Kang, Jeon Min Kang, Dae Sung Ryu, Min Young Kwak, Ho-Young Song, Jung-Hoon Park, Hong Ju Park
Summary: This study evaluated the technical feasibility of stent placement and histological changes in a porcine Eustachian tube model. Stent placement was successful in all specimens, with tissue hyperplasia and severe inflammatory cell infiltration observed after 4 weeks. Different stent diameters and locations affected luminal configuration and tissue response.
APPLIED SCIENCES-BASEL
(2021)
Article
Chemistry, Multidisciplinary
Dae-Sung Ryu, Joon-Myeong Choi, Woo-Jin Kim, Jeon-Min Kang, Ki-Baek Lee, Yu-Been Park, Dong-Sung Won, Ji-Won Kim, Song-Hee Kim, Pyeong-Hwa Kim, Song-Cheol Kim, Jung-Hoon Park
Summary: The research shows that increasing the number of flaps on a plastic stent can significantly improve anti-migration effects in 3D-printed pancreatic phantoms and extracted porcine pancreases. However, the direction of the flaps does not affect the anti-migration force, while the position of the flaps attached to the stent surface does influence the anti-migration force.
APPLIED SCIENCES-BASEL
(2021)
Article
Chemistry, Multidisciplinary
Ji Won Kim, Hee Ho Chu, Dong-Sung Won, Chu Hui Zeng, Song Hee Kim, Yubeen Park, Jeon Min Kang, Dae Sung Ryu, Ji Hoon Shin, Jung-Hoon Park
Summary: This study investigated the occlusive properties of newly developed transrenal ureteral occlusion self-expanding metallic stents (SEMSs). The results showed that M- and D-type occlusion SEMSs had similar occlusive properties in the 3D phantom model, but in the ex vivo porcine urinary tract model, the M-type SEMS performed better in terms of occlusive properties compared to the D-type SEMS.
APPLIED SCIENCES-BASEL
(2022)
Article
Chemistry, Multidisciplinary
Jeon Min Kang, Dongwook Oh, Song Hee Kim, Dae Sung Ryu, Yubeen Park, Dong-Sung Won, Ji Won Kim, Chu Hui Zeng, Jung-Hoon Park, Sang Soo Lee
Summary: This study found that interwoven self-expandable metallic stent (I-SEMS) placement is more effective in suppressing stent-induced tissue hyperplasia compared to conventional knitted self-expandable metallic stent (K-SEMS) placement in a rat esophageal model.
APPLIED SCIENCES-BASEL
(2022)
Article
Pharmacology & Pharmacy
Yubeen Park, Dong-Sung Won, Ga-Hyun Bae, Dae Sung Ryu, Jeon Min Kang, Ji Won Kim, Song Hee Kim, Chu Hui Zeng, Wooram Park, Sang Soo Lee, Jung-Hoon Park
Summary: The efficacy of silver nanoparticles-coated self-expandable metal stents (SEMSs) in inhibiting tissue hyperplasia and bacterial growth caused by radiofrequency ablation with stent placement was investigated in a rabbit model. The results demonstrated that the AgNPs-coated SEMS significantly suppressed bacterial activity and tissue hyperplasia, suggesting that this approach could be a promising treatment option for thermal damage and stent-related complications.
Article
Chemistry, Multidisciplinary
Jun-Hyeok Han, Ha Eun Shin, Jiyoung Lee, Jeon Min Kang, Jung-Hoon Park, Chun Gwon Park, Dong Keun Han, Ik-Hwan Kim, Wooram Park
Summary: In this study, a novel nanoparticle in combination with irreversible electroporation (IRE) was developed for effective cancer immunotherapy. The nanoparticle, synthesized and coated, can be effectively internalized by antigen-presenting cells and trigger an immune response. Notably, the nanoparticle demonstrated longer retention time in the tumor compared to the free drug. Tailored IRE expanded the ablation zone and enhanced therapeutic efficacy. Ultimately, the combined treatment successfully inhibited tumor growth and prolonged survival.
Article
Engineering, Biomedical
Eunyoung Jeon, Jeon Min Kang, Ga-Hyun Bae, Chu Hui Zeng, Seungyong Shin, Byeongdu Lee, Wooram Park, Jung-Hoon Park, Joonseok Lee
Summary: A flexible 3D nanonetworked silica film (NSF) was developed as a drug delivery platform for self-expandable metallic stents (SEMSs), capable of withstanding mechanical stress during dynamic expansion and improving therapeutic effects.
ADVANCED HEALTHCARE MATERIALS
(2022)
Letter
Clinical Neurology
Ye Eun Sun, Han Kyu Na, Soomin Kwak, Young Dae Kim, Hyo Suk Nam, Ji Hoe Heo
Article
Oncology
Seung Jeong, Song Hee Kim, Hongbae Kim, Jeon Min Kang, Yubeen Park, Dong-Sung Won, Ji Won Kim, Dae Sung Ryu, Chu Hui Zeng, Jong Hoon Chung, Bumjin Lim, Jung-Hoon Park
Summary: HF-PEF is a safe and effective method for inducing ablation and tissue regeneration in prostate cancer.
Article
Clinical Neurology
Han Kyu Na, Han-Kyeol Kim, Hye Sun Lee, Mina Park, Jae Hoon Lee, Young Hoon Ryu, Hanna Cho, Chul Hyoung Lyoo
Summary: By studying 272 participants with MRI and PET scans, we found that a high degree of temporal lobe perivascular space (EPVS) is associated with a higher likelihood of amyloid positivity in patients with Alzheimer's disease. This finding suggests that impaired perivascular drainage may be related to cerebral amyloidosis.
ANNALS OF NEUROLOGY
(2023)
Article
Clinical Neurology
Kyoungwon Baik, Hye Ryun Kim, Mincheol Park, Younggun Lee, Han Kyu Na, Young H. H. Sohn, Joon-Kyung Seong, Phil Hyu Lee
Summary: This study investigated the effect of amyloid accumulation on cognitive dysfunction in patients with Parkinson's disease and dementia with Lewy bodies. The results showed that while the burden of amyloid was higher in the dementia with Lewy bodies group, amyloid accumulation was negatively associated with memory and language functions only in the Parkinson's disease group.
MOVEMENT DISORDERS
(2023)
Article
Clinical Neurology
Jin Ho Jung, Han Kyu Na, Seong Ho Jeong, Seok Jong Chung, Han Soo Yoo, Yang Hyun Lee, Kyoungwon Baik, Sang Jin Kim, Young H. Sohn, Phil Hyu Lee
Summary: This study suggests that Dihydropyridines (DHPs) may have neuroprotective effects in patients with Parkinson's disease (PD) and hypertension. The use of DHPs was associated with a lower risk of developing dementia in hypertensive patients with PD.
MOVEMENT DISORDERS
(2023)
Article
Multidisciplinary Sciences
Jeon Min Kang, Song Hee Kim, Dae Sung Ryu, Yubeen Park, Dong-Sung Won, Ji Won Kim, Chu Hui Zeng, Jung-Hoon Park, Hong Ju Park
Summary: The degradable behavior and efficacy of absorbable magnesium (Mg) stents in the Eustachian tube (ET) were investigated. The mass loss rate of the Mg stents gradually decreased over time, with significant reduction in tissue hyperplasia and inflammatory cell infiltration observed at four weeks. The Mg stent biodegraded before tissue proliferative reactions and maintained ET patency without inducing tissue hyperplasia. Rapidly degradable Mg stents appear to be effective and safe in the porcine ET, but further investigation is needed.
Article
Clinical Neurology
Jin Ho Jung, Han Kyu Na, Seong Ho Jeong, Seok Jong Chung, Han Soo Yoo, Yang Hyun Lee, Kyoungwon Baik, Sang Jin Kim, Young H. Sohn, Phil Hyu Lee
Summary: This study suggests that DHPs may be associated with better long-term cognitive outcomes in hypertensive patients with PD.
MOVEMENT DISORDERS
(2023)
Letter
Clinical Neurology
Sungwoo Kang, So Hoon Yoon, Han Kyu Na, Young-gun Lee, Seun Jeon, Kyoungwon Baik, Young H. Sohn, Byoung Seok Ye
JOURNAL OF CLINICAL NEUROLOGY
(2023)