Review
Medicine, General & Internal
Hae Do Jung, Seok Cho, Joo Yong Lee
Summary: Microbiota plays a role in kidney stone formation through various mechanisms, including hyperoxaluria, calcium oxalate supersaturation, biofilm formation, and urothelial injury. The urinary tract microbiome differs between cohorts with and without urinary stone disease, and certain bacteria are associated with stone formation. Standardization is essential in urinary microbiome research for urolithiasis.
Article
Agriculture, Dairy & Animal Science
Salome Azevedo, Bairbre O'Malley, Claire Greene, Helena Moran, Tomas Rodrigues Magalhaes, Felisbina Luisa Queiroga
Summary: The clinical records of guinea pigs diagnosed with lower urinary tract disease in a veterinary hospital over a 14-year period were retrospectively searched. The most common diagnosis was urolithiasis, followed by cystitis/UTI. Female guinea pigs were more likely to have a family history of urinary disease, abnormal micturition signs, and recurrence. Males were more prone to urolithiasis, while females were more prone to cystitis/UTI. The use of potassium citrate and urethrotomy showed a better therapeutic response. Further studies are needed to confirm these findings in larger populations of guinea pigs.
Article
Medicine, General & Internal
Seok Cho, Min Gu Park, Keon-Cheol Lee, Sung Yong Cho, Jeong Woo Lee
Summary: The study investigated 203 febrile patients with upper urinary tract calculi who were hospitalized and received antibiotic treatment. The most commonly cultured microorganism was Escherichia coli. Multivariate analysis revealed that calculi's multiplicity was an independent predictive factor for quinolone resistance, while recurrent infections were a significant predictor of cefotaxime resistance.
JOURNAL OF KOREAN MEDICAL SCIENCE
(2021)
Article
Medicine, General & Internal
Wei-Hung Wang, Tian-Hoe Tan, Chung-Han Ho, Yi-Chen Chen, Chien-Chin Hsu, Hung-Jung Lin, Jhi-Joung Wang, Yen-Wei Chiu, Chien-Cheng Huang
Summary: This study demonstrates an association between osteoarthritis and urinary tract infection in older adults. In addition to osteoarthritis, age, gender, history of urinary tract infection, and other comorbidities were identified as independent predictors for urinary tract infection. Therefore, appropriate management of osteoarthritis and control of underlying comorbidities are recommended to prevent urinary tract infection.
Article
Geriatrics & Gerontology
Kyungmi Woo, Victoria Adams, Paula Wilson, Li-Heng Fu, Kenrick Cato, Sarah Collins Rossetti, Margaret McDonald, Jingjing Shang, Maxim Topaz
Summary: This study developed a natural language processing algorithm to automatically identify UTI-related information in nursing notes. The frequency of UTI-related information documentation increased in advance of UTI-related hospitalization or ED admission, peaking within a few days before the event.
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2021)
Article
Urology & Nephrology
Jake Herbert, Emily Teeter, Landen Shane Burstiner, Ralfi Doka, Amor Royer, Anna H. Owings, Julia Liu, Sarah C. Glover, Pegah Hosseini-Carroll
Summary: This study found similar rates of urolithiasis formation in both UC and CD patients, and a higher proportion of African American patients developed uncomplicated UTI compared to Caucasian patients. There was no significant difference in the rates of urinary extra-intestinal manifestations between African American and Caucasian populations with IBD.
Review
Chemistry, Medicinal
Lukasz Dobrek
Summary: A potential complication of pharmacotherapy is the possibility of various drug side effects, which can cause diseases. Among the systemic side effects, there are also those involving the urinary tract. The use of certain drugs may increase the risk of urological disorders, such as urinary retention or incontinence, urinary tract infections, urolithiasis, erectile dysfunction, and retroperitoneal fibrosis.
Article
Veterinary Sciences
Jana Weinekoetter, Corinne Gurtner, Martina Protschka, Wolf von Bomhard, Denny Boettcher, Annika Schlinke, Gottfried Alber, Sarah Roesch, Joerg M. Steiner, Johannes Seeger, Gerhard U. Oechtering, Romy M. Heilmann
Summary: This study aimed to evaluate the tissue expression of S100/calgranulins and the blood NLR in dogs with UC. The results showed that the expression of S100A12 was significantly increased in dogs with lower urinary tract disease. NLR has the potential to distinguish UC from inflammatory conditions, and higher NLRs are associated with poor survival time.
BMC VETERINARY RESEARCH
(2022)
Article
Medicine, General & Internal
Cong Zhu, Dan-Qi Wang, Hao Zi, Qiao Huang, Jia-Min Gu, Lu-Yao Li, Xing-Pei Guo, Fei Li, Cheng Fang, Xiao-Dong Li, Xian-Tao Zeng
Summary: Over the past three decades, the disease burden has increased for UTI but decreased for urolithiasis and BPH. Allocation of medical resources should be based more on the epidemiological characteristics and geographical distribution of diseases.
MILITARY MEDICAL RESEARCH
(2021)
Review
Immunology
Virginia Perez-Carrasco, Ana Soriano-Lerma, Miguel Soriano, Jose Gutierrez-Fernandez, Jose A. Garcia-Salcedo
Summary: The application of next generation sequencing techniques has revealed that the urinary tract is not sterile, contrary to previous beliefs. Microbial communities in the urinary tract play a crucial role in maintaining health and are associated with various urinary pathologies. Understanding the urinary microbiome in health and disease could lead to the development of new therapeutic strategies.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2021)
Article
Medicine, General & Internal
Marie Tran, Khelifa Ait Said, Benjamin Menahem, Remy Morello, Xavier Tillou
Summary: Malabsorption and an increased risk of kidney stone formation are consequences of gastric bypass surgery. This study developed a screening questionnaire to accurately assess the risk of lithiasis in this population. The questionnaire showed high sensitivity and specificity, with a score of ≥6 indicating a high risk of kidney stone formation.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Multidisciplinary Sciences
Agnes Cottalorda, Sandrine Dahyot, Anais Soares, Kevin Alexandre, Isabelle Zorgniotti, Manuel Etienne, Estelle Jumas-Bilak, Martine Pestel-Caron
Summary: This study assessed the phenotypic and molecular diversity of Pseudomonas aeruginosa isolates responsible for urinary tract infection and asymptomatic bacteriuria. The results showed a high level of diversity in both antimicrobial resistance and genetic background among the isolates.
SCIENTIFIC REPORTS
(2022)
Article
Medicine, General & Internal
Amanda E. Hird, Refik Saskin, Ying Liu, Yuna Lee, Khaled Ajib, Rano Matta, Ronald Kodama, Lesley Carr, Girish S. Kulkarni, Sender Herschorn, Steven A. Narod, Robert K. Nam
Summary: This study found that patients with chronic bladder catheterisation had a higher risk of developing bladder cancer and bladder cancer-specific mortality compared to the general population, especially among those with a chronic catheter duration beyond 2.9 years.
Article
Medicine, General & Internal
Offir Ukashi, Yiftach Barash, Eyal Klang, Tal Zilberman, Bella Ungar, Uri Kopylov, Shomron Ben-Horin, Ido Veisman
Summary: This study indicates that patients with IBD have higher rates of hospitalization, acute kidney injury (AKI), and 30-day recurrent hospitalization compared to non-IBD patients in UTI treatment. Among IBD patients, older age, recent hospitalization, hydronephrosis, and AKI are associated with increased risk for adverse outcomes. There is no association observed between immunosuppressants or biologics and UTI outcomes in IBD patients.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Urology & Nephrology
Yang Liu, Huimin Zhang, Zhi Wen, Yu Jiang, Jing Huang, Chongjian Wang, Caixia Chen, Jiahao Wang, Erhao Bao, Xuesong Yang
Summary: In the treatment of upper urinary tract calculi, the advantages and disadvantages of retrograde intrarenal surgery (RIRS) and minimally invasive percutaneous nephrolithotomy (mPCNL) have not been conclusively determined. This meta-analysis comprehensively evaluated the performance of the two surgical approaches. A total of 18 eligible randomized controlled trials (RCTs) involving 1733 patients were included in the analysis. The results of the meta-analysis showed that mPCNL had a higher stone clearance rate and shorter operation time compared to RIRS, but it was associated with longer hospital stay time, hemoglobin drops, blood transfusion rate, pain visual analogue score, hospital costs, and major complications.