Nuclear receptor RORα regulates pathologic retinal angiogenesis by modulating SOCS3-dependent inflammation

ROR Inverse Agonist Suppresses Insulitis and Prevents Hyperglycemia in a Mouse Model of Type 1 Diabetes

(2015) Laura A. Solt et al.   ENDOCRINOLOGY

Autocrine CCL2, CXCL4, CXCL9 and CXCL10 signal in retinal endothelial cells and are enhanced in diabetic retinopathy

(2013) M.I. Nawaz et al.   EXPERIMENTAL EYE RESEARCH

Inflammation and Pharmacological Treatment in Diabetic Retinopathy

(2013) Snježana Kaštelan et al.   MEDIATORS OF INFLAMMATION

SOCS3 is an endogenous inhibitor of pathologic angiogenesis

(2012) A. Stahl et al.   BLOOD

Pivotal Role of Rho-Associated Kinase 2 in Generating the Intrinsic Circadian Rhythm of Vascular Contractility

(2012) Toshiro Saito et al.   CIRCULATION

Examining the role of lipid mediators in diabetic retinopathy

(2012) Julia V Busik et al.   Clinical Lipidology

Retinoic-Acid-Receptor-Related Orphan Nuclear Receptor Alpha Is Required for Natural Helper Cell Development and Allergic Inflammation

(2012) Timotheus Y.F. Halim et al.   IMMUNITY

SOCS3 Deficiency Promotes M1 Macrophage Polarization and Inflammation

(2012) H. Qin et al.   JOURNAL OF IMMUNOLOGY

High Vitreous Concentration of IL-6 and IL-8, but Not of Adhesion Molecules in Relation to Plasma Concentrations in Proliferative Diabetic Retinopathy

(2012) U.E. Koskela et al.   OPHTHALMIC RESEARCH

Interleukin-1β Inhibition Prevents Choroidal Neovascularization and Does Not Exacerbate Photoreceptor Degeneration

(2011) Sophie Lavalette et al.   AMERICAN JOURNAL OF PATHOLOGY

Widespread Negative Response Elements Mediate Direct Repression by Agonist- Liganded Glucocorticoid Receptor

(2011) Milan Surjit et al.   CELL

Suppression of TH17 differentiation and autoimmunity by a synthetic ROR ligand

(2011) Laura A. Solt et al.   NATURE

Influence of ROBO1 and RORA on Risk of Age-Related Macular Degeneration Reveals Genetically Distinct Phenotypes in Disease Pathophysiology

(2011) Gyungah Jun et al.   PLoS One

Identification of SR1078, a Synthetic Agonist for the Orphan Nuclear Receptors RORα and RORγ

(2010) Yongjun Wang et al.   ACS Chemical Biology

Prospective Study of Common Variants in the Retinoic Acid Receptor–Related Orphan Receptor α Gene and Risk of Neovascular Age-Related Macular Degeneration

(2010) Debra A. Schaumberg   ARCHIVES OF OPHTHALMOLOGY

Antioxidant or neurotrophic factor treatment preserves function in a mouse model of neovascularization-associated oxidative stress

(2009) Michael I. Dorrell et al.   JOURNAL OF CLINICAL INVESTIGATION

Simultaneous Analyses of Vitreous Levels of 27 Cytokines in Eyes with Retinopathy of Prematurity

(2009) Tatsuhiko Sato et al.   OPHTHALMOLOGY

The nuclear receptor RORα exerts a bi-directional regulation of IL-6 in resting and reactive astrocytes

(2009) Nathalie Journiac et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aging, age-related macular degeneration, and the response-to-retention of apolipoprotein B-containing lipoproteins

(2009) Christine A. Curcio et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Convergence of linkage, gene expression and association data demonstrates the influence of the RAR-related orphan receptor alpha (RORA) gene on neovascular AMD: A systems biology based approach

(2009) Alexandra C. Silveira et al.   VISION RESEARCH

T Helper 17 Lineage Differentiation Is Programmed by Orphan Nuclear Receptors RORα and RORγ

(2008) Xuexian O. Yang et al.   IMMUNITY

Retinoic acid receptor-related orphan receptor α regulates a subset of cone genes during mouse retinal development

(2008) Hiroki Fujieda et al.   JOURNAL OF NEUROCHEMISTRY