Detecting cancers through tumor-activatable minicircles that lead to a detectable blood biomarker

Safety and efficacy of DNA vaccines

(2014) Sofia Stenler et al.   Human Vaccines & Immunotherapeutics

Micro-minicircle Gene Therapy: Implications of Size on Fermentation, Complexation, Shearing Resistance, and Expression

(2014) Sofia Stenler et al.   Molecular Therapy-Nucleic Acids

A nanoparticle formulation that selectively transfects metastatic tumors in mice

(2013) Jian Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Systemic delivery of a breast cancer-detecting adenovirus using targeted microbubbles

(2012) J M Warram et al.   CANCER GENE THERAPY

Why Your New Cancer Biomarker May Never Work: Recurrent Patterns and Remarkable Diversity in Biomarker Failures

(2012) S. E. Kern   CANCER RESEARCH

Mass-encoded synthetic biomarkers for multiplexed urinary monitoring of disease

(2012) Gabriel A Kwong et al.   NATURE BIOTECHNOLOGY

Single DermaVir Immunization: Dose-Dependent Expansion of Precursor/Memory T Cells against All HIV Antigens in HIV-1 Infected Individuals

(2012) Julianna Lisziewicz et al.   PLoS One

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Potent, tumor-specific gene expression in an orthotopic hepatoma rat model using a Survivin-targeted, amplifiable adenoviral vector

(2011) B-C Ahn et al.   GENE THERAPY

Cancer Screening by Systemic Administration of a Gene Delivery Vector Encoding Tumor-Selective Secretable Biomarker Expression

(2011) Andrew W. Browne et al.   PLoS One

Bioluminescence resonance energy transfer (BRET) imaging of protein-protein interactions within deep tissues of living subjects

(2011) A. Dragulescu-Andrasi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mathematical Model Identifies Blood Biomarker-Based Early Cancer Detection Strategies and Limitations

(2011) S. S. Hori et al.   Science Translational Medicine

Micro-NMR for Rapid Molecular Analysis of Human Tumor Samples

(2011) J. B. Haun et al.   Science Translational Medicine

Rationale and design of Enhanced Angiogenic Cell Therapy in Acute Myocardial Infarction (ENACT-AMI): The first randomized placebo-controlled trial of enhanced progenitor cell therapy for acute myocardial infarction

(2010) Monica Taljaard et al.   AMERICAN HEART JOURNAL

pFARs, Plasmids free of antibiotic resistance markers, display high-level transgene expression in muscle, skin and tumour cells

(2010) Corinne Marie et al.   JOURNAL OF GENE MEDICINE

Cancer Biomarkers: Can We Turn Recent Failures into Success?

(2010) E. P. Diamandis   JNCI-Journal of the National Cancer Institute

A Genetic Strategy for Combined Screening and Localized Imaging of Breast Cancer

(2010) Jason M. Warram et al.   MOLECULAR IMAGING AND BIOLOGY

A robust system for production of minicircle DNA vectors

(2010) Mark A Kay et al.   NATURE BIOTECHNOLOGY

Tumor-specific imaging through progression elevated gene-3 promoter-driven gene expression

(2010) Hyo-eun C Bhang et al.   NATURE MEDICINE

Cancer-Specific Transgene Expression Mediated by Systemic Injection of Nanoparticles

(2009) E. J. Chisholm et al.   CANCER RESEARCH

A Potent, Imaging Adenoviral Vector Driven by the Cancer-selective Mucin-1 Promoter That Targets Breast Cancer Metastasis

(2009) S. T. Huyn et al.   CLINICAL CANCER RESEARCH

Tumor regression after systemic administration of a novel tumor-targeted gene delivery system carrying a therapeutic plasmid DNA

(2009) Swati Koppu et al.   JOURNAL OF CONTROLLED RELEASE

A strategy for blood biomarker amplification and localization using ultrasound

(2009) A. L. D'Souza et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cancer gene therapy with targeted adenoviruses

(2008) Houria Bachtarzi et al.   Expert Opinion on Drug Delivery

Phase I/II Marker Lesion Study of Intravesical BC-819 DNA Plasmid in H19 Over Expressing Superficial Bladder Cancer Refractory to Bacillus Calmette-Guerin

(2008) Abraham Ami Sidi et al.   JOURNAL OF UROLOGY

Noninvasive Imaging of Therapeutic Gene Expression Using a Bidirectional Transcriptional Amplification Strategy

(2008) Sunetra Ray et al.   MOLECULAR THERAPY

The Immunogenicity of Adenovirus Vectors Limits the Multispecificity of CD8 T-cell Responses to Vector-encoded Transgenic Antigens

(2008) Reinhold Schirmbeck et al.   MOLECULAR THERAPY

Systemic Delivery of DNA or siRNA Mediated by Linear Polyethylenimine (L-PEI) Does Not Induce an Inflammatory Response

(2008) Marie-Elise Bonnet et al.   PHARMACEUTICAL RESEARCH

Evaluation of systemic and mucosal anti-HPV16 and anti-HPV18 antibody responses from vaccinated women

(2008) Troy J. Kemp et al.   VACCINE