CBR antimicrobials inhibit RNA polymerase via at least two bridge-helix cap-mediated effects on nucleotide addition

The Ratcheted and Ratchetable Structural States of RNA Polymerase Underlie Multiple Transcriptional Functions

(2015) Shun-ichi Sekine et al.   MOLECULAR CELL

Coliphage HK022 Nun protein inhibits RNA polymerase translocation

(2014) C. L. Vitiello et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CBR antimicrobials alter coupling between the bridge helix and the β subunit in RNA polymerase

(2014) Anssi M. Malinen et al.   Nature Communications

Transcription inhibition by the depsipeptide antibiotic salinamide A

(2014) David Degen et al.   eLife

X-ray Crystal Structure ofEscherichia coliRNA Polymerase σ70Holoenzyme

(2013) Katsuhiko S. Murakami   JOURNAL OF BIOLOGICAL CHEMISTRY

Control of Transcriptional Fidelity by Active Center Tuning as Derived from RNA Polymerase Endonuclease Reaction

(2013) Ekaterina Sosunova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cys-Pair Reporters Detect a Constrained Trigger Loop in a Paused RNA Polymerase

(2013) Dhananjaya Nayak et al.   MOLECULAR CELL

The Mechanism of E. coli RNA Polymerase Regulation by ppGpp Is Suggested by the Structure of their Complex

(2013) Yuhong Zuo et al.   MOLECULAR CELL

Interplay between the trigger loop and the F loop during RNA polymerase catalysis

(2013) Nataliya Miropolskaya et al.   NUCLEIC ACIDS RESEARCH

Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of  70 domain 1.1

(2013) B. Bae et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A grid-enabled web service for low-resolution crystal structure refinement

(2012) Daniel J. O'Donovan et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Active site opening and closure control translocation of multisubunit RNA polymerase

(2012) Anssi M. Malinen et al.   NUCLEIC ACIDS RESEARCH

Interaction of RNA Polymerase II Fork Loop 2 with Downstream Non-template DNA Regulates Transcription Elongation

(2011) Maria L. Kireeva et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activity Map of theEscherichia coliRNA Polymerase Bridge Helix

(2011) Milija Jovanovic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tackling antibiotic resistance

(2011) Karen Bush et al.   NATURE REVIEWS MICROBIOLOGY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

The nucleotide addition cycle of RNA polymerase is controlled by two molecular hinges in the Bridge Helix domain

(2010) Robert OJ Weinzierl   BMC BIOLOGY

Stepwise mechanism for transcription fidelity

(2010) Yulia Yuzenkova et al.   BMC BIOLOGY

The bridge helix coordinates movements of modules in RNA polymerase

(2010) Pyae P Hein et al.   BMC BIOLOGY

Super-resolution biomolecular crystallography with low-resolution data

(2010) Gunnar F. Schröder et al.   NATURE

Central role of the RNA polymerase trigger loop in intrinsic RNA hydrolysis

(2010) Y. Yuzenkova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

electronic Ligand Builder and Optimization Workbench(eLBOW): a tool for ligand coordinate and restraint generation

(2009) Nigel W. Moriarty et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

4-Bromo-N-phenylbenzamidoxime

(2009) Mihaela Cibian et al.   ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE

Mutational studies of archaeal RNA polymerase and analysis of hybrid RNA polymerases

(2009) Michael Thomm et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Molecular Evolution of Multisubunit RNA Polymerases: Structural Analysis

(2009) William J. Lane et al.   JOURNAL OF MOLECULAR BIOLOGY

Structural Basis of Transcription: Mismatch-Specific Fidelity Mechanisms and Paused RNA Polymerase II with Frayed RNA

(2009) Jasmin F. Sydow et al.   MOLECULAR CELL

Allosteric control of catalysis by the F loop of RNA polymerase

(2009) Nataliya Miropolskaya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Basis of Transcription: Backtracked RNA Polymerase II at 3.4 Angstrom Resolution

(2009) D. Wang et al.   SCIENCE

The RNA Polymerase “Switch Region” Is a Target for Inhibitors

(2008) Jayanta Mukhopadhyay et al.   CELL

Transcription inactivation through local refolding of the RNA polymerase structure

(2008) Georgiy A. Belogurov et al.   NATURE

Rifamycins do not function by allosteric modulation of binding of Mg2+ to the RNA polymerase active center

(2008) A. Feklistov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA