Article
Acoustics
Douglas L. L. Miller, Chunyan Dou, Zhihong Dong
Summary: This study evaluated the dependency of pulmonary capillary hemorrhage (PCH) on frames per second (fps), on-screen mechanical index (MIOS), and thermal index (TI) in lung ultrasound imaging. The results showed that PCH increased at low fps, while there was minimal PCH at an MIOS setting of 0.5. Therefore, the study suggests some value for the use of the mechanical index as a predictive indicator of PCH.
JOURNAL OF ULTRASOUND IN MEDICINE
(2023)
Article
Acoustics
Yaxin Hu, Jianpeng Wei, Yuanyuan Shen, Siping Chen, Xin Chen
Summary: Emerging evidence has shown that cavitation creates bidirectional channels for drug delivery and biomarker release. This study reviews recent advancements in ultrasound and contrast agents, as well as details the cellular responses and vascular effects of cavitation. The article also highlights the current achievements in using cavitation for drug delivery and biomarker release, while acknowledging the challenges of precise induction and proposes methods for in-situ cavitation imaging and feedback control for clinical guidance.
ULTRASONICS SONOCHEMISTRY
(2023)
Review
Acoustics
Jacques S. Abramowicz, Srikar Adhikari, Eitan Dickman, Judy A. Estroff, Gerald R. Harris, Jason Nomura, Ronald H. Silverman, Lindsay A. Taylor, Richard G. Barr
Summary: Ocular ultrasound is essential for evaluating the eye and orbit, but caution must be taken due to their sensitivity to the thermal and mechanical effects of ultrasound. It is important to use dedicated ocular settings during B-mode imaging, and to adjust settings to reduce acoustic output in Doppler modes to comply with FDA recommendations.
JOURNAL OF ULTRASOUND IN MEDICINE
(2022)
Article
Acoustics
Jafar Fatahi Asl, Zahra Farzanegan, Marziyeh Tahmasbi, Shadab Moradi Birgani, Mehrnaz Malekzade, Hamid Yazdaninejad
Summary: The study aimed to assess the scan duration, TI, and MI as measures of acoustic output during ultrasound studies. The results indicated that the reported ultrasound scans were safe.
JOURNAL OF ULTRASOUND IN MEDICINE
(2021)
Article
Acoustics
Hao Xue, Weifeng Yu, Zhonghua Liu, Peizhong Liu
Summary: In this study, a lightweight target detection network is proposed for early pregnancy fetal facial ultrasound standard plane recognition and quality assessment. The clinical control protocol and the YOLOv4 target detection algorithm are utilized to accurately identify standard planes, providing essential information for disease diagnosis.
JOURNAL OF ULTRASOUND IN MEDICINE
(2023)
Article
Computer Science, Interdisciplinary Applications
Jacopo Dapueto, Luca Zini, Francesca Odone
Summary: In clinical practice, the selection of ultrasound standard planes (SPs) is subjective and inconsistent. This paper proposes a method for automatic identification of SPs on a portable ultrasound system with limited computational power. The deep learning methodology uses knowledge distillation to transfer knowledge from a well-performing teacher network to a smaller student network.
MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING
(2023)
Article
Acoustics
Maciej Piskunowicz, Anush Sridharan, Laura Poznick, Elizabeth Silvestro, Misun Hwang
Summary: Increasing the mechanical index (MI) during contrast-enhanced ultrasound (CEUS) examinations can improve contrast-to-tissue ratio and image quality, as the default MI set by the manufacturer is often suboptimal.
JOURNAL OF ULTRASOUND IN MEDICINE
(2021)
Article
Acoustics
Douglas L. Miller, Chunyan Dou, Krishnan Raghavendran, Zhihong Dong
Summary: This study found that the presence of hemorrhagic shock significantly reduces the occurrence of lung ultrasound-induced pulmonary capillary hemorrhage.
JOURNAL OF ULTRASOUND IN MEDICINE
(2021)
Article
Computer Science, Information Systems
Juncheng Guo, Guanghua Tan, Fan Wu, Huaxuan Wen, Kenli Li
Summary: A novel detection framework is proposed to improve the efficiency and accuracy of ultrasound standard plane detection. By utilizing both coarse-to-fine detection strategy and multi-task learning mechanism, the proposed method achieves better performance in prenatal fetal growth parameter measurement and disease diagnosis. The workload of sonographers in prenatal screening can be reduced effectively.
IEEE JOURNAL OF BIOMEDICAL AND HEALTH INFORMATICS
(2023)
Article
Automation & Control Systems
Bin Pu, Kenli Li, Shengli Li, Ningbo Zhu
Summary: An automatic fetal ultrasound standard plane recognition model based on deep learning is proposed in this article for intelligent medical care in the IIoT environment. The model deployed in the HPC center consists of CNN and RNN components to learn spatial and temporal features of ultrasound videos, achieving precise localization and tracking of fetal organs. Feature fusion strategies such as CNN fusion and RNN fusion are introduced to improve the accuracy and robustness of the model, as demonstrated through extensive experiments on over 1000 ultrasound videos.
IEEE TRANSACTIONS ON INDUSTRIAL INFORMATICS
(2021)
Article
Acoustics
Louise M. Steele, Troy J. Kotsch, Catherine A. Legge, Delores J. Smith
Summary: Ultrasound is widely used in medical procedures and research, with potential bioeffects on animals such as altered survival, movement, reproduction, development, and learning. Exposing C. elegans to ultrasound resulted in reduced movement, fecundity, and survival, which could be prevented by polyvinyl alcohol, indicating cavitation as the main mechanism of damage. This study lays a foundation for further exploring ultrasound's bioeffects at the cellular and molecular levels using C. elegans as a model organism.
ULTRASOUND IN MEDICINE AND BIOLOGY
(2021)
Article
Medicine, General & Internal
Jing Qiu, Yanhui Ru, Yang Gao, Jie Shen
Summary: The feasibility and value of prenatal ultrasound for the diagnosis of microtia were explored by analyzing the ultrasound features, associated anomalies, and genetic abnormalities of 81 fetuses with congenital microtia. Among the cases, there were missed diagnoses and misdiagnoses on prenatal ultrasound, and microtia was often accompanied by congenital defects of other organs and structures. Prenatal ultrasound diagnosis of microtia and associated anomalies is of important clinical significance.
FRONTIERS IN MEDICINE
(2023)
Article
Acoustics
Douglas L. Miller, Chunyan Dou, Krishnan Raghavendran, Zhihong Dong
Summary: The induction of pulmonary capillary hemorrhage by lung ultrasound is influenced by physical exposure parameters, physiological conditions, and drug treatment. Xylazine and clonidine tend to increase susceptibility to lung ultrasound-induced PCH, with higher sensitivity in spontaneously hypertensive rats compared to normotensive rats and regardless of mean systemic blood pressure levels.
ULTRASOUND IN MEDICINE AND BIOLOGY
(2021)
Article
Endocrinology & Metabolism
Dakshita Jagota, Hannah George, Melissa Walker, Anjana Ravi Chandran, Natasha Milligan, Shiri Shinar, Clare L. Whitehead, Sebastian R. Hobson, Lena Serghides, W. Tony Parks, Ahmet A. Baschat, Christopher K. Macgowan, John G. Sled, John C. Kingdom, Lindsay S. Cahill
Summary: The study showed that in healthy pregnancies, Doppler ultrasound parameters for some vessels are dependent on fetal sex, while for others they are not. Further research is needed to understand the physiological mechanisms behind these sex differences and their relevance for disease processes in pregnancy.
BIOLOGY OF SEX DIFFERENCES
(2021)
Article
Acoustics
Priya S. Balasubramanian, Amit Lal
Summary: This study investigates the effects of gigahertz ultrasound and electrical stimulus on the morphology, functionality, and viability of neural cells. Results show that gigahertz ultrasound and electrical stimulus can alter cell morphology and excite neural cells.
IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL
(2022)
Editorial Material
Acoustics
Jacques S. Abramowicz
JOURNAL OF ULTRASOUND IN MEDICINE
(2020)
Article
Computer Science, Hardware & Architecture
Brendan L. West, Jian Zhou, Ronald G. Dreslinski, Oliver D. Kripfgans, J. Brian Fowlkes, Chaitali Chakrabarti, Thomas F. Wenisch
IEEE TRANSACTIONS ON COMPUTERS
(2020)
Article
Urology & Nephrology
Kourosh Kalayeh, J. Brian Fowlkes, William W. Schultz, Bryan S. Sack
Summary: Our study confirms the importance of the UVJ length-to-diameter ratio in preventing reflux. As the bladder volume increases, the UVJ length-to-diameter ratio decreases, leading to UVJ closure and an increase in flow resistance. The surgical implementation based on this observation results in an overestimation of the required tunnel length-to-diameter ratio.
NEUROUROLOGY AND URODYNAMICS
(2021)
Review
Radiology, Nuclear Medicine & Medical Imaging
Jacques S. Abramowicz
Summary: Diagnostic ultrasound (DUS) has evolved rapidly in obstetrical practice, from A mode to three-dimensional/four-dimensional ultrasound, with the application of artificial intelligence expected to further advance the technology. New visualization methods, expanded training approaches, and improvements in workflow and ergonomics may be seen in the future.
Article
Computer Science, Hardware & Architecture
Jian Zhou, Sumit K. Mandal, Brendan L. West, Siyuan Wei, Umit Y. Ogras, Oliver D. Kripfgans, J. Brian Fowlkes, Thomas F. Wenisch, Chaitali Chakrabarti
Summary: 3-D ultrasound imaging offers advantages over 2-D for more accurate tumor and cyst analysis, but 3-D systems face challenges with data processing speed for power-constrained portable systems. Synthetic aperture sequential beamforming (SASB) resolves this by splitting computation into two stages.
IEEE TRANSACTIONS ON VERY LARGE SCALE INTEGRATION (VLSI) SYSTEMS
(2021)
Article
Engineering, Biomedical
Leidan Huang, Carole Quesada, Mitra Aliabouzar, J. Brian Fowlkes, Renny T. Franceschi, Zheng Liu, Andrew J. Putnam, Mario L. Fabiilli
Summary: Vascularization following tissue implantation is crucial for viability, and the ability to spatially control this process using acoustically responsive scaffolds has been demonstrated in this study. The study found that spatially-defined patterns of acoustic droplet vaporization can elicit spatially-defined patterns of angiogenesis.
ACTA BIOMATERIALIA
(2021)
Letter
Acoustics
Jacques S. Abramowicz
JOURNAL OF ULTRASOUND IN MEDICINE
(2022)
Article
Multidisciplinary Sciences
Elizabeth A. Paris, Janice M. Bahr, Pincas Bitterman, Sanjib Basu, Jacques S. Abramowicz, Animesh Barua
Summary: The study found that tumors in the oviductal fimbria of hens exhibit similarities to ovarian high grade serous carcinoma (HGSC) in patients, expressing similar markers. This suggests that tumors in the oviductal fimbria of hens may serve as a preclinical model for studying various aspects of spontaneous ovarian HGSC in women, including early detection.
Article
Environmental Sciences
Rick Tinker, Jacques Abramowicz, Efthymios Karabetsos, Sigurour Magnusson, Rudiger Matthes, Mirjana Moser, Shengli Niu, John O'Hagan, Emilie van Deventer
Summary: Currently, there is no coherent and overarching framework for health protection from non-ionising radiation (NIR). The World Health Organization's international framework aims to promote a globally consistent approach for NIR protection and provide guidance to governments on achieving effective protection, especially in the context of rapidly developing new technologies.
JOURNAL OF RADIOLOGICAL PROTECTION
(2022)
Review
Acoustics
Kenneth B. Bader, Inder Raj S. Makin, Jacques S. Abramowicz
Summary: Aesthetic ultrasound is utilized for fat reduction and skin improvement, with various technologies available or in development. Recommendations for safe and effective use of aesthetic ultrasound are provided.
JOURNAL OF ULTRASOUND IN MEDICINE
(2022)
Article
Acoustics
Roni Yoeli-Bik, Ernst Lengyel, Kathryn A. Mills, Jacques S. Abramowicz
Summary: Adnexal lesions are common in women and most of them are benign, requiring a conservative approach. Transvaginal ultrasound plays a key role in evaluating the risk of malignancy, but recognizing the acoustic shadow is a difficult skill to master and its usefulness may be underestimated.
JOURNAL OF ULTRASOUND IN MEDICINE
(2023)
Review
Radiology, Nuclear Medicine & Medical Imaging
David T. Fetzer, Ivan M. Rosado-Mendez, Michael Wang, Michelle L. Robbin, Arinc Ozturk, Keith A. Wear, Juvenal Ormachea, Timothy A. Stiles, J. Brian Fowlkes, Timothy J. Hall, Anthony E. Samir
Summary: Excessive liver fat is the most common cause of chronic liver disease worldwide and is a significant risk factor for cirrhosis and associated complications. This article discusses the efforts of AIUM and RSNA QIBA in developing clinical and technical validation standards for quantitative biomarkers of liver steatosis.
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
J. Brian Fowlkes
Article
Mechanics
Kourosh Kalayeh, Haotian Xie, J. Brian Fowlkes, Bryan S. Sack, William W. Schultz
Summary: For the first time, this study takes into account the longitudinal motion of the walls during peristalsis in a distensible tube and its effect on backward flow, or peristaltic reflux. Using an analytical model based on lubrication theory, the study models peristalsis as a two-dimensional infinite sinusoidal wavetrain. The study develops an objective function to find optimal peristalsis conditions with high mechanical pumping efficiency and low reflux. The results show that optimal wall longitudinal motion significantly limits reflux during peristalsis, in agreement with clinical observations of ureteral peristalsis.
JOURNAL OF FLUID MECHANICS
(2023)
Article
Physics, Applied
Mitra Aliabouzar, Bachir A. Abeid, Oliver D. Kripfgans, J. Brian Fowlkes, Jonathan B. Estrada, Mario L. Fabiilli
Summary: Phase-shift droplets generated a range of bioeffects via the mechanism of acoustic droplet vaporization (ADV), which could be applied in therapeutic and diagnostic ultrasound. This study visualized ADV-induced mechanics and sonoporation in fibrin-based hydrogels using ultra-high-speed microscopy, confocal microscopy, and focused ultrasound. The results showed that fibrin gels containing perfluoropentane (PFP) droplets exhibited significantly higher radial expansion, expansion velocity, induced strain, and displacement of tracer particles compared to gels containing perfluorohexane (PFH) or perfluorooctane (PFO) droplets. Cell membrane permeabilization was dependent on the distance between the droplet and cell, decreasing rapidly with increasing distance. The hyper-local region of influence by an ADV bubble correlated inversely with the boiling point of the phase-shift droplets. These findings provide insights for the development of optimal approaches for therapeutic applications of ADV.
APPLIED PHYSICS LETTERS
(2023)
