Article
Pediatrics
Gavriela Maria Feketea, Ioana Corina Bocsan, Georgios Tsiros, Panagiota Voila, Luminita Aurelia Stanciu, Mihnea Zdrenghea
Summary: This study in Greece found a high prevalence of vitamin D deficiency/insufficiency among healthy children and adolescents, with significant seasonal variation. The use of sunscreen during summer months was associated with higher serum levels of 25(OH)D, suggesting the importance of vitamin D supplementation during months with lower sun exposure.
Article
Food Science & Technology
Ying Wu, Fang Wang, Aiguo Li, Jiangfang Gao, Bosheng Li, Huiming Sheng, Jun Ma, Xiang-Peng Liao
Summary: This study aims to describe the vitamin D status among healthy infants and children in Shanghai, China. The results show that low vitamin D status is common in this population, highlighting the importance of assessing 25(OH)D levels in individuals at risk for deficiency or excess.
FOOD SCIENCE & NUTRITION
(2023)
Article
Nutrition & Dietetics
Souzana E. Xyda, Kalliopi Kotsa, Argyrios Doumas, Emmanouil Papanastasiou, Alexandros A. Garyfallos, George Samoutis
Summary: The prevalence of vitamin D deficiency is paradoxically high in both Mediterranean countries, Greece and Cyprus, despite ample sunlight in the region. Only the month and gender were significantly associated with vitamin D levels.
Article
Nutrition & Dietetics
Elodie Chartron, Nelly Firmin, Celia Touraine, Angelique Chapelle, Eric Legouffe, Lobna Rifai, Stephane Pouderoux, Lise Roca, Veronique D'Hondt, William Jacot
Summary: The study investigated the safety and efficacy of high-dose oral vitamin D supplementation in correcting vitamin D deficiency in early breast cancer patients receiving adjuvant chemotherapy. Results showed that the supplementation was safe and efficient, although some patients experienced adverse reactions such as hypercalciuria.
Article
Pediatrics
Limin Yang, Miori Sato, Mayako Saito-Abe, Makoto Irahara, Minaho Nishizato, Hatoko Sasaki, Mizuho Konishi, Kazue Ishitsuka, Hidetoshi Mezawa, Kiwako Yamamoto-Hanada, Yukihiro Ohya
Summary: This study aimed to obtain epidemiological data on vitamin D levels for the pediatric population in Japan. The results showed that vitamin D deficiency and insufficiency are very common among 2-year-old Japanese children, with factors such as sex, season, and latitude affecting serum 25(OH) D concentrations.
Article
Nutrition & Dietetics
Faruk Ahmed, Hossein Khosravi-Boroujeni, Moududur Rahman Khan, Anjan Kumar Roy, Rubhana Raqib
Summary: This study found that hypovitaminosis D is highly prevalent among pregnant rural Bangladeshi women. Parity and gestational age are common risk factors for vitamin D deficiency and insufficiency, while a husband's occupation and anaemia status may predict vitamin D insufficiency. Younger age and sub-optimal vitamin A status are risk factors for vitamin D deficiency in this population.
Review
Endocrinology & Metabolism
Konstantina D. Vaitsi, Panagiotis Anagnostis, Stavroula Veneti, Theodosios S. Papavramidis, Dimitrios G. Goulis
Summary: Preoperative vitamin D deficiency is associated with an increased risk of transient hypoparathyroidism following thyroidectomy, especially for patients with severe deficiency. However, the risk of permanent hypoparathyroidism is only increased in cases with severe deficiency.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Review
Nutrition & Dietetics
Zaleha Md Isa, Norizzati Amsah, Norfazilah Ahmad
Summary: Vitamin D deficiency and insufficiency have negative effects on the outcome of Type 2 Diabetes Mellitus patients, including glycaemic control and the development of complications. Thus, screening for vitamin D levels in T2DM patients may be beneficial.
Article
Pediatrics
Huawei Wang, Yiming Du, Zhixin Wu, Haifeng Geng, Xueping Zhu, Xiaoli Zhu
Summary: This study investigated the status of serum vitamin D in hospitalized full-term neonates in eastern China. The study found that the prevalence of vitamin D insufficiency was 28.24%, and factors such as season of birth, gestational age, maternal health, and perinatal complications were associated with vitamin D levels.
FRONTIERS IN PEDIATRICS
(2022)
Review
Neurosciences
Michela Barichella, Federica Garri, Serena Caronni, Carlotta Bolliri, Luciano Zocchi, Maria Carmela Macchione, Valentina Ferri, Daniela Calandrella, Gianni Pezzoli
Summary: Parkinson's disease is a neurodegenerative disorder characterized by motor symptoms and various non-motor symptoms. Recent research has suggested a potential correlation between vitamin D and Parkinson's disease, although the mechanisms and efficacy are still unclear.
Article
Nutrition & Dietetics
Ting-Yi Wang, Hung-Wei Wang, Ming-Yan Jiang
Summary: This study investigated the prevalence of vitamin D deficiency and its association with mortality risk among non-institutional middle-aged and older adults in the United States. The results showed that nearly 20% of the study population were vitamin D deficient and vitamin D deficiency was associated with increased mortality risk.
FRONTIERS IN NUTRITION
(2023)
Article
Nutrition & Dietetics
Maria Minter, Hanna Augustin, Jenny van Odijk, Lowie E. G. W. Vanfleteren
Summary: This study aimed to assess vitamin D status and determinants of vitamin D insufficiency in patients with COPD in Southwestern Sweden. The results showed that vitamin D insufficiency is common in patients with COPD and is related to male gender, smoking habits, lack of supplements containing vitamin D, and the winter season for blood sampling.
Article
Nutrition & Dietetics
Kuo-Chuan Hung, Sheng-Hsiang Yang, Chia-Yu Chang, Li-Kai Wang, Yao-Tsung Lin, Chia-Hung Yu, Min-Hsiang Chuang, Jen-Yin Chen
Summary: A meta-analysis of 16 observational studies revealed a negative association between serum vitamin D levels and the risk of VTE. This association remained significant in subgroup analyses and in the presence of neurological diseases. Individuals with vitamin D deficiency had an increased risk of VTE compared to those with normal levels.
Article
Nutrition & Dietetics
Simon Hsu, David K. Prince, Kayleen Williams, Norrina B. Allen, Gregory L. Burke, Andrew N. Hoofnagle, Xiaohui Li, Kiang J. Liu, Robyn L. McClelland, Erin D. Michos, Bruce M. Psaty, Steven J. Shea, Kenneth M. Rice, Jerome Rotter, David Siscovick, Russell P. Tracy, Karol E. Watson, Bryan R. Kestenbaum, Ian H. de Boer
Summary: The study found that only participants with a baseline 25(OH)D level below 20 ng/mL had a significant reduction in parathyroid hormone (PTH) with vitamin D supplementation.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2022)
Article
Nutrition & Dietetics
Tomozumi Takatani, Yuzuka Kunii, Mamoru Satoh, Akifumi Eguchi, Midori Yamamoto, Kenichi Sakurai, Rieko Takatani, Fumio Nomura, Naoki Shimojo, Chisato Mori
Summary: The correlation between maternal vitamin D concentrations and birth outcomes is conflicting. This study found that the maternal vitamin D metabolite ratio, specifically VMR2, is associated with neonatal anthropometric data regardless of 25(OH)D concentrations. Accurate measurement of vitamin D metabolites can help understand the effects of vitamin D on birth outcomes.
Article
Clinical Neurology
Nejat Mahdieh, Ameneh Sharifi, Ali Rabbani, Mahmoudreza Ashrafi, Ali Reza Tavasoli, Reza Shervin Badv, Joshua L. Bonkowsky, Bahareh Rabbani
Summary: The study investigated the genotype-phenotype spectrum of MLD patients in Iran, identifying several novel disease-causing variants and highlighting the presence of alternative causes for leukodystrophy in some individuals. The most frequent alleles among Iranian MLD patients were c.931 G > A (p.Gly311Ser) and c.465 + 1 G > A variants, with five mutations appearing to be specific to this population. Population screening for these variants could help reduce the disease burden in this region.
CLINICAL NEUROLOGY AND NEUROSURGERY
(2021)
Review
Mycology
Hamid Eshaghi, Leila Moradi, Parvaneh Adimi, Mohammad Gharagozlou, Masoud Movahedi, Nima Parvaneh
Summary: Invasive Rasamsonia spp. infections are rare and often associated with chronic granulomatous disease (CGD). We reported a case of pulmonary and possible cerebral infection caused by Rasamsonia argillacea in a CGD girl who did not receive primary antifungal prophylaxis, resulting in a fatal outcome despite antifungal therapy and surgical interventions. A literature review on reported invasive Rasamsonia spp. infections in the context of CGD was also conducted.
JOURNAL DE MYCOLOGIE MEDICALE
(2021)
Article
Multidisciplinary Sciences
Nejat Mahdieh, Mahdieh Soveizi, Ali Reza Tavasoli, Ali Rabbani, Mahmoud Reza Ashrafi, Alfried Kohlschuetter, Bahareh Rabbani
Summary: This study evaluated the genetic spectrum of leukodystrophies and leukoencephalopathies in Iran, identifying 35 different types of genetic disorders. Genetic analysis at earlier stages of the disease can reduce uncertainty, costs, and provide basis for genetic counseling and family planning.
SCIENTIFIC REPORTS
(2021)
Article
Pediatrics
Shima Mahmoudi, Bahareh Yaghmaei, Meisam Sharifzadeh Ekbatani, Babak Pourakbari, Amene Navaeian, Nima Parvaneh, Mohammad Taghi Haghi Ashtiani, Setareh Mamishi
Summary: This study described lymphocyte subsets in pediatric patients with mild/moderate or severe COVID-19. Results showed that patients with severe disease had lower lymphocyte counts, higher CD8(+) T cell count, lower CD4(+) T cell percentage, and a lower CD4(+)/CD8(+) T cell ratio compared to those with mild/moderate disease. The study suggested that a decrease in CD4(+)/CD8(+) ratio may serve as a useful metric in analyzing immune responses in severe COVID-19 patients, but further research with larger sample sizes is recommended.
FRONTIERS IN PEDIATRICS
(2021)
Article
Genetics & Heredity
Bahareh Rabbani, Mohammadrafi Khorgami, Mohammad Dalili, Nasrin Zamani, Nejat Mahdieh, Michael H. Gollob
Summary: TRDN mutations can lead to CPVT, but may present with LQTS on ECG. Two cases of sudden cardiac death due to TRDN mutations provide further insight into this rare inherited arrhythmia syndrome. The average age of onset for patients is 30 months, with adrenergic-mediated cardiac events being the main manifestation.
AMERICAN JOURNAL OF MEDICAL GENETICS PART A
(2021)
Article
Clinical Neurology
Katayoun Heshmatzad, Mahya Haghi Panah, Ali Reza Tavasoli, Mahmoud Reza Ashrafi, Nejat Mahdieh, Bahareh Rabbani
Summary: This study conducted a comprehensive analysis of Infantile AxD caused by GFAP mutations, highlighting that seizure is the most common clinical symptom, with most variants located in specific domains of the protein, and four common variants responsible for nearly half of the patients.
CLINICAL NEUROLOGY AND NEUROSURGERY
(2021)
Review
Developmental Biology
Sima Binaafar, Masoud Garshasbi, Ali Reza Tavasoli, Reza Shervin Badv, Seyyed Mohammad Mahdi Hosseiny, Debopam Samanta, Bahareh Rabbani, Nejat Mahdieh
Summary: The study focused on patients with nonsyndromic early-onset epileptic encephalopathy (NSEOEE) and reported 2 novel cases from Iran. Through genetic and phenotypic analysis, significant impact of KCTD7 gene mutations on NSEOEE was identified, emphasizing the importance of careful consideration in data analysis. The study also highlighted the diverse geographical distribution and potential therapeutic opportunities for KCTD7-related NSEOEE.
DEVELOPMENTAL NEUROSCIENCE
(2021)
Article
Immunology
Anna-Lena Neehus, Kunihiko Moriya, Alejandro Nieto-Patlan, Tom Le Voyer, Romain Levy, Ahmet Ozen, Elif Karakoc-Aydiner, Safa Baris, Alisan Yildiran, Engin Altundag, Manon Roynard, Kathrin Haake, Melanie Migaud, Karim Dorgham, Guy Gorochov, Laurent Abel, Nico Lachmann, Figen Dogu, Sule Haskologlu, Erdal Ince, Jamel El-Benna, Gulbu Uzel, Ayca Kiykim, Kaan Boztug, Marion R. Roderick, Mohammad Shahrooei, Paul A. Brogan, Hassan Abolhassani, Gonca Hancioglu, Nima Parvaneh, Alexandre Belot, Aydan Ikinciogullari, Jean-Laurent Casanova, Anne Puel, Jacinta Bustamante
Summary: Patients with autosomal recessive protein kinase C delta deficiency exhibit childhood-onset autoimmunity and recurrent infections similar to chronic granulomatous disease (CGD) patients, possibly due to impaired NADPH oxidase activity.
JOURNAL OF EXPERIMENTAL MEDICINE
(2021)
Article
Immunology
Mahdieh Vahedi, Nima Parvaneh, Saeedeh Vahedi, Mohammad Shahrooei, Vahid Ziaee
Summary: This study reported a case of a 1-year-old boy with recurrent urticarial rash and joint pain and swelling, with a missense mutation c.G1060 T (p.A354S) in exon 5 of the NLRP3 gene detected by whole exome sequencing. The novel variant in the NLRP3 gene has not been reported previously.
CASE REPORTS IN IMMUNOLOGY
(2021)
Article
Gastroenterology & Hepatology
Zahra Goudarzi, Abdollah Poursamad, Iman Karimzadeh, Nahid Jallaly, Khosro Keshavarz, Seyed Moayed Alavian
Summary: The study evaluated the cost-effectiveness of three medication regimens for HCV genotype 1 patients in Iran. Results indicated that VEL/SOF regimen was the most cost-effective strategy, followed by LDV/SOF and DCV/SOF.
Article
Dermatology
Hassan Vahidnezhad, Leila Youssefian, Amir Hossein Saeidian, Vahid Ziaee, Hamidreza Mahmoudi, Nima Parvaneh, Bahar Ashjaei, Soroush Shahrokh, Kambiz Kamyab Hesari, Mohammadsadegh Soltani Zangbar, Mehdi Yousefi, Sirous Zeinali, Jouni Uitto
Summary: This case series study identified a new form of possible autosomal recessive PAAND in a consanguineous family with 2 affected children and confirmed the association of a biallelic MEFV variation with the disease through genetic analysis. Treatment with colchicine and low-dose prednisolone under genotype guidance showed positive response.
Review
Microbiology
Mohammadreza Pourkarim, Shahnaz Nayebzadeh, Seyed Moayed Alavian, Seyyed Hassan Hataminasab
Summary: New technologies supported by the internet have brought significant changes to various scientific disciplines, including the healthcare sector. Innovative digital marketing strategies that utilize social media and user data have improved diagnostic, prophylaxis, and treatment services in healthcare. The use of social media and mobile health apps during the COVID-19 pandemic has demonstrated the importance of these platforms in local and global health policies.
Correction
Clinical Neurology
Bahareh Rabbani, Mohammad Kazem Bakhshandeh, Mohammad Reza Navaeifar, Ali Abbaskhanian, Mahdieh Soveizi, Shahpour Geravandpoor, Nejat Mahdieh
JOURNAL OF CLINICAL NEUROSCIENCE
(2022)
Article
Gastroenterology & Hepatology
Mousa Imani, Heidar Sharafi, Akram Sadeh, Rezvan Kakavand-Ghalehnoei, Seyed Moayed Alavian, Akbar Fotouhi
Summary: This study investigated the prevalence of HBV and HCV serum markers in people with severe mental illnesses in Tehran, Iran, and found that HCV infection was more common in this population. Therefore, preventive, diagnostic, and therapeutic interventions for HCV infection are necessary for people with severe mental illnesses in Iran.
Article
Endocrinology & Metabolism
Parisa Nikasa, Bahareh Rabbani, Mohammad Saeid Hejazi, Ata Firouzi, Hossein Baharvand, Mehdi Totonchi, Nejat Mahdieh
CLINICAL PEDIATRIC ENDOCRINOLOGY
(2021)
