High dose lansoprazole combined with metronomic chemotherapy: a phase I/II study in companion animals with spontaneously occurring tumors

Escalation with overdose control using all toxicities and time to event toxicity data in cancer Phase I clinical trials

(2014) Zhengjia Chen et al.   Contemporary Clinical Trials

Exosome Release and Low pH Belong to a Framework of Resistance of Human Melanoma Cells to Cisplatin

(2014) Cristina Federici et al.   PLoS One

Combining low-dose or metronomic chemotherapy with anticancer vaccines

(2014) Heng Sheng Sow et al.   OncoImmunology

A dose-escalating phase I of imatinib mesylate with fixed dose of metronomic cyclophosphamide in targeted olid tumours

(2013) A Adenis et al.   BRITISH JOURNAL OF CANCER

Metronomic administration of chlorambucil for treatment of dogs with urinary bladder transitional cell carcinoma

(2013) Diane R. Schrempp et al.   JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION

Proton pump inhibitor chemosensitization in human osteosarcoma: from the bench to the patients’ bed

(2013) Stefano Ferrari et al.   Journal of Translational Medicine

A phase II trial of a multi-agent oral antiangiogenic (metronomic) regimen in children with recurrent or progressive cancer

(2013) Nathan J. Robison et al.   PEDIATRIC BLOOD & CANCER

Modulation of Microenvironment Acidity Reverses Anergy in Human and Murine Tumor-Infiltrating T Lymphocytes

(2012) A. Calcinotto et al.   CANCER RESEARCH

Systemic Buffers Inhibit Carcinogenesis in TRAMP Mice

(2012) Arig Ibrahim-Hashim et al.   JOURNAL OF UROLOGY

Clinical and Immunomodulatory Effects of Toceranib Combined with Low-Dose Cyclophosphamide in Dogs with Cancer

(2012) L. Mitchell et al.   JOURNAL OF VETERINARY INTERNAL MEDICINE

Bicarbonate and dichloroacetate: Evaluating pH altering therapies in a mouse model for metastatic breast cancer

(2011) Ian F Robey et al.   BMC CANCER

First-line metronomic chemotherapy in a metastatic model of spontaneous canine tumours: a pilot study

(2011) Veronica Marchetti et al.   INVESTIGATIONAL NEW DRUGS

Lansoprazole as a rescue agent in chemoresistant tumors: a phase I/II study in companion animals with spontaneously occurring tumors

(2011) Enrico P Spugnini et al.   Journal of Translational Medicine

Prospective trial of metronomic chlorambucil chemotherapy in dogs with naturally occurring cancer

(2011) T. N. Leach et al.   Veterinary and Comparative Oncology

Proton pump inhibitors as anti vacuolar-ATPases drugs: a novel anticancer strategy

(2010) Enrico P Spugnini et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Proton pump inhibitor-induced tumour cell death by inhibition of a detoxification mechanism

(2010) S. Fais   JOURNAL OF INTERNAL MEDICINE

Proton dynamics in cancer

(2010) Veronica Huber et al.   Journal of Translational Medicine

Bicarbonate Increases Tumor pH and Inhibits Spontaneous Metastases

(2009) I. F. Robey et al.   CANCER RESEARCH

Metronomic Therapy with Cyclophosphamide and Piroxicam Effectively Delays Tumor Recurrence in Dogs with Incompletely Resected Soft Tissue Sarcomas

(2009) R.E. Elmslie et al.   JOURNAL OF VETERINARY INTERNAL MEDICINE

Function, structure and regulation of the vacuolar (H+)-ATPases

(2008) Kevin C. Jefferies et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Structure and regulation of the vacuolar ATPases

(2008) Daniel J. Cipriano et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS