Article
Environmental Sciences
Fabio Jose Targino Moreira da Silva Junior, Joanna Damazio Nunes Ribeiro, Hugo Leandro Azevedo da Silva, Carla da Silva Carneiro, Edgar Francisco Oliveira de Jesus, Ubiratan Barbosa de Araujo, Stella Maris Lazzarini, Aline Ramos Souza, Julia Siqueira Simoes, Ricardo Tadeu Lopes, Marcelino Jose dos Anjos, Micheli da Silva Ferreira, Eliane Teixeira Marsico
Summary: This study analyzed the concentrations of multiple elements and total mercury in different organs and tissues of Amazonian manatees. The findings suggest that non-essential trace elements accumulate in the body of these animals, even in manatees kept in a conservation center. Differences were observed in the accumulation of elements in different organs and tissues.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Environmental Sciences
Wenqiang Lv, Tianli Zhan, Mahmoud A. Abdelhafiz, Xinbin Feng, Bo Meng
Summary: The study showed that the addition of biochar and sodium selenite-amended biochar can reduce MeHg generation in paddy soil and effectively mitigate MeHg accumulation in rice. The 5% BC + Se treatment had the most significant impact on reducing MeHg levels in rice grains.
ENVIRONMENTAL POLLUTION
(2021)
Article
Engineering, Environmental
Yuping Xiang, Ailing Zhu, Yingying Guo, Guangliang Liu, Baowei Chen, Bin He, Yong Liang, Yongguang Yin, Yong Cai, Guibin Jiang
Summary: Iron sulfide nanoparticles (FeSNp) have shown to significantly reduce the bioavailability of both Hg(II) and MeHg in aquatic environments, inhibiting MeHg production and integration into food webs, although there is a potential risk of release when the sorbed contaminants are oxidized, increasing exposure risk to aquatic organisms. These findings provide valuable information for the development of in situ Hg remediation systems.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Engineering, Environmental
Xiaoquan Liu, Yingjun Wang, Zheng Li, Yue Song, Yanbin Li, Yongguang Yin, Yong Cai
Summary: Riverine mercury is a major source of mercury in coastal oceans, and the Yellow River is the main contributor to mercury contamination in the Bohai Sea. Suspended particulate matter plays a dominant role in the transport of mercury in the river-estuary system. The study highlights distinct patterns in the distribution and transport of total mercury and methylmercury.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Pharmacology & Pharmacy
Xue Tian, Xiaoying Lin, Jiating Zhao, Liwei Cui, Yuxi Gao, Yong-Liang Yu, Bai Li, Yu-Feng Li
Summary: Mercury (Hg) is harmful to the environment and human health. This review paper summarizes the impacts of inorganic Hg (IHg) and methyl Hg (MeHg) on gut barriers and extraintestinal effects, shedding light on the importance of considering the gut as a target tissue for Hg exposure.
Article
Environmental Sciences
Miyuki Iwai-Shimada, Yayoi Kobayashi, Tomohiko Isobe, Shoji E. Nakayama, Makiko Sekiyama, Yu Taniguchi, Shin Yamazaki, Takehiro Michikawa, Masako Oda, Hiroshi Mitsubuchi, Masafumi Sanefuji, Shouichi Ohga, Nathan Mise, Akihiko Ikegami, Reiko Suga, Masayuki Shimono
Summary: Prenatal exposure to methylmercury can impact child development. This study compared two high-throughput methods for mercury speciation and found relatively good agreement between them. MeHg and IHg concentrations were determined in maternal and cord blood samples, highlighting the importance of analyzing different chemical forms for health effects.
Article
Environmental Sciences
Shaun T. Lancaster, Gabriela Peniche, Ali Alzahrani, Magdalena Blanz, Jason Newton, Mark A. Taggart, Warren T. Corns, Eva M. Krupp, Joerg Feldmann
Summary: Understanding the uptake and fate of mercury compounds in biota is crucial for understanding the global mercury cycling and its transfer through food chains. This study analyzed mercury concentrations in Scottish birds of prey and found the presence of mercury selenide nanoparticles in the liver of some golden eagles, which has not been observed in terrestrial birds of prey before. The study suggests that these nanoparticles may be formed as a detoxification mechanism or accumulated through foraging on stranded cetaceans or seabirds.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Environmental Sciences
Poul Bjerregaard, Lise Marianne Moller
Summary: The laboratory experiments showed that sea stars accumulated the highest concentrations of methylmercury and inorganic mercury in their digestive glands and pyloric caeca after being fed contaminated mussels for 49 days. Steady states were reached for both mercury forms in the sea stars during the 7-week feeding period, with concentrations approximately 1/2 and 1/4 of the levels found in the mussel food. Additionally, the sea stars eliminated inorganic mercury faster than methylmercury during a 140-day elimination period following the feeding period.
ENVIRONMENTAL POLLUTION
(2021)
Article
Medicine, General & Internal
Siu Chung Anson So, Man Fung Tsoi, Adrian Justin Cheung, Tommy Tsang Cheung, Bernard M. Y. Cheung
Summary: The study found that organic mercury levels in the blood of the US population, including children and pregnant women, increased significantly from 1999 to 2016. However, there was a steady decline in both blood inorganic mercury and urine mercury levels during the same period.
AMERICAN JOURNAL OF MEDICINE
(2021)
Article
Environmental Sciences
Tao Sun, Qing Xie, Chuxian Li, Jinyong Huang, Caipeng Yue, Xuejie Zhao, Dingyong Wang
Summary: Both inorganic and organic fertilizers increase the concentration of methylmercury (MeHg) in rice grains, but through different mechanisms. Inorganic fertilizers enhance mercury methylation by increasing the bioavailability of mercury and the relative amount of Hg-methylating microbes. In contrast, organic matter in organic fertilizers is the main driver for the increase in MeHg concentrations in rice grains and can also immobilize mercury in soil.
ENVIRONMENTAL POLLUTION
(2022)
Article
Chemistry, Multidisciplinary
Ying-Jie Li, Qi Lin, Zheng-Hua Zhang, Tai-Bao Wei, Bingbing Shi, Hong Yao, You-Ming Zhang
Summary: Numerous new methods have been developed for synthesizing novel nanomaterials with unique functions. One novel strategy involves forming fluorescent nanoparticles in situ, which can efficiently sense Hg2+ in living cells and separate Hg2+ from water.
Article
Environmental Sciences
Ting Sun, Zoe Lindo, Brian A. A. Branfireun
Summary: Climate change-driven ground warming will alter mercury cycling processes in high boreal and subarctic peatlands, particularly increasing MeHg production in subarctic peatlands. Increased soil temperature promotes microbial metabolism and organic matter turnover, resulting in higher concentrations of MeHg in the water.
FRONTIERS IN ENVIRONMENTAL SCIENCE
(2023)
Article
Environmental Sciences
J. Margaret Castellini, Lorrie D. Rea, Julie P. Avery, Todd M. O'Hara
Summary: Steller sea lions in Alaska exhibit elevated levels of mercury in their tissues, potentially impacting population recovery. The interactions between selenium and monomethylmercury may alleviate toxicity but can also lead to selenium deficiency. Tissue concentrations of mercury, selenium, and monomethylmercury vary across age cohorts, making interpretation challenging. Fetal and pup tissues are ideal for assessing mercury exposure related to maternal diet.
ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
(2022)
Article
Environmental Sciences
V Mangal, W. Y. Lam, H. Huang, E. J. S. Emilson, R. W. Mackereth, C. P. J. Mitchell
Summary: This study investigates the molecular composition of dissolved organic matter (DOM) and its relationship with mercury transport and transformations. High-resolution mass spectrometry is used to characterize DOM compound classes, DOM aromaticity, and the nominal oxygenation state of carbon across thirteen small boreal forest streams in central Canada. The results show significant differences in the abundance and classes of DOM compounds correlated with inorganic mercury and methylmercury concentrations across seasons and between mercury forms. Nitrogen and sulfur containing DOM compounds are most often positively correlated with inorganic mercury concentrations in late spring, while low-oxidized lignins are more important in fall. Low-oxidized lignins and hydrolysable tannins account for a large proportion of DOM-MeHg correlations, regardless of season. The study also reveals that the strongest correlations between inorganic mercury and DOM occur across a wide range of carbon oxygenation states, suggesting that DOM involved in inorganic mercury transport encompasses a wide range of polarities and thermodynamic stabilities. In contrast, DOM molecules exclusively correlated with MeHg concentrations have more positive carbon oxygenation states and aromatic qualities, indicating preferential transport of MeHg with more stable and aromatic DOM molecules. DOM molecules correlated with both inorganic mercury and MeHg concentrations are only found in late spring.
Article
Environmental Sciences
Hongxia Du, Pan Guo, Tao Wang, Ming Ma, Dingyong Wang
Summary: The bioaccumulation of MeHg in edible organisms living in the rice-based ecosystem was significantly higher than in paddy soils and rice roots, even though total Hg levels were higher in rice roots and grains. This indicates a potential elevated MeHg exposure risk through consumption, especially for local residents. The study highlights the importance of reducing the consumption of rice, eels, and loaches to mitigate MeHg exposure risks.
ENVIRONMENTAL POLLUTION
(2021)
Article
Pharmacology & Pharmacy
Claudia S. Oliveira, Lucy Joshee, Rudolfs K. Zalups, Maria E. Pereira, Christy C. Bridges
Article
Pharmacology & Pharmacy
Christy C. Bridges, Rudolfs K. Zalups, Lucy Joshee
TOXICOLOGY AND APPLIED PHARMACOLOGY
(2015)
Review
Toxicology
Christy C. Bridges, Rudolfs K. Zalups
ARCHIVES OF TOXICOLOGY
(2017)
Article
Geriatrics & Gerontology
Claudia S. Oliveira, Lucy Joshee, Rudolfs K. Zalups, Christy C. Bridges
EXPERIMENTAL GERONTOLOGY
(2016)
Review
Biochemistry & Molecular Biology
Sarah E. Orr, Christy C. Bridges
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2017)
Article
Biochemistry & Molecular Biology
Sarah E. Orr, Renee C. Franklin, Hannah S. George, Sanya Nijhara, Lucy Joshee, Christy C. Bridges
BIOLOGICAL TRACE ELEMENT RESEARCH
(2018)
Article
Environmental Sciences
Sarah E. Orr, Lucy Joshee, Jennifer Barkin, Christy C. Bridges
JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES
(2018)
Article
Environmental Sciences
Kristen G. Williams, Kayla T. Patel, Julie M. Stausmire, Christy Bridges, Mary W. Mathis, Jennifer L. Barkin
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2018)
Article
Environmental Sciences
Sarah E. Orr, Mary C. Barnes, Hannah S. George, Lucy Joshee, Byunggwon Jeon, Austin Scircle, Oscar Black, James V. Cizdziel, Betsy E. Smith, Christy C. Bridges
JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES
(2018)
Article
Toxicology
Sarah E. Orr, Mary C. Barnes, Lucy Joshee, Olga Uchakina, Robert J. McKallip, Christy C. Bridges
TOXICOLOGY LETTERS
(2019)
Article
Biochemistry & Molecular Biology
Sarah E. Orr, Hannah S. George, Mary C. Barnes, Taylor N. Mathis, Lucy Joshee, Jennifer Barkin, Adam M. Kiefer, Caryn S. Seney, Christy C. Bridges
BIOLOGICAL TRACE ELEMENT RESEARCH
(2020)
Article
Biochemistry & Molecular Biology
Srividya Ganapathy, Elisa R. Farrell, Simran Vaghela, Lucy Joshee, Earl G. Ford, Olga Uchakina, Robert J. McKallip, Jennifer L. Barkin, Christy C. Bridges
Summary: This study assessed the transport of MeHg into placental syncytiotrophoblasts and characterized the mechanisms by which it exerts toxic effects. MeHg compounds were found to be transported into cells primarily by sodium-independent amino acid carriers and organic anion transporters. MeHg altered mitochondrial function and viability, decreased mitophagy and autophagy, and increased oxidative stress. Exposure to higher concentrations of MeHg inhibited the ability of cells to protect against MeHg-induced injury.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Toxicology
Delon W. Barfuss, John T. Buchanan, Lucy Joshee, Elizabeth H. Pittman, Nigel D' Souza, Kayla E. Matta, Ryan T. Brownlee, Christy C. Bridges
Summary: This study demonstrates that circulating Hg-albumin complexes are taken up by hepatocytes and processed to form GSH-Hg-GSH, which is then exported back into blood via MRP3 and MRP5. These findings are significant for understanding the excretion mechanism of Hg in the body.
TOXICOLOGY LETTERS
(2022)
Review
Biochemistry & Molecular Biology
Manish Mishra, Larry Nichols, Aditi A. Dave, Elizabeth H. Pittman, John P. Cheek, Anasalea J. Caroland, Purva Lotwala, James Drummond, Christy C. Bridges
Summary: Chronic kidney disease is a common condition with major risk factors including diabetes, hypertension, and obesity. This disease leads to the loss of functional nephrons and cellular injury, with remaining nephrons undergoing changes to compensate. However, these changes can contribute to additional injury and disease progression.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Claudia Oliveira, Lucy Joshee, Christy C. Bridges
BIOLOGICAL TRACE ELEMENT RESEARCH
(2018)
