A novel mutation in the P2Y12receptor and a function-reducing polymorphism in protease-activated receptor 1 in a patient with chronic bleeding

Evaluation of participants with suspected heritable platelet function disorders including recommendation and validation of a streamlined agonist panel

(2012) B. B. Dawood et al.   BLOOD

GPCR activation: a mutagenic spotlight on crystal structures

(2012) Edward C. Hulme   TRENDS IN PHARMACOLOGICAL SCIENCES

An intact PDZ motif is essential for correct P2Y12 purinoceptor traffic in human platelets

(2011) S. Nisar et al.   BLOOD

Identification and analysis of functionally important amino acids in human purinergic 12 receptor using a Saccharomyces cerevisiae expression system

(2011) Vita Ignatovica et al.   FEBS Journal

The Significance of G Protein-Coupled Receptor Crystallography for Drug Discovery

(2011) J. A. Salon et al.   PHARMACOLOGICAL REVIEWS

P2 receptors and platelet function

(2011) Béatrice Hechler et al.   Purinergic Signalling

Structural insights into adrenergic receptor function and pharmacology

(2011) Brian K. Kobilka   TRENDS IN PHARMACOLOGICAL SCIENCES

The platelet P2Y12 receptor for adenosine diphosphate: congenital and drug-induced defects

(2010) M. Cattaneo   BLOOD

Impact of the DRY Motif and the Missing "Ionic Lock" on Constitutive Activity and G-Protein Coupling of the Human Histamine H4 Receptor

(2010) E. H. Schneider et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Identification and characterization of a novel P2Y12 variant in a patient diagnosed with type 1 von Willebrand disease in the European MCMDM-1VWD study

(2009) M. E. Daly et al.   BLOOD

A novel thromboxane A2 receptor D304N variant that abrogates ligand binding in a patient with a bleeding diathesis

(2009) A. D. Mumford et al.   BLOOD

Ligand binding and micro-switches in 7TM receptor structures

(2009) Rie Nygaard et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Rapid resensitization of purinergic receptor function in human platelets

(2008) S. J. MUNDELL et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

G Protein–Coupled Receptor Sorting to Endosomes and Lysosomes

(2007) Adriano Marchese et al.   Annual Review of Pharmacology and Toxicology