期刊
JOURNAL OF THORACIC ONCOLOGY
卷 4, 期 4, 页码 444-447出版社
ELSEVIER SCIENCE INC
DOI: 10.1097/JTO.0b013e31819d6f91
关键词
MET pathway; Therapeutic target; Thoracic tumorigenesis
资金
- NCI NIH HHS [R01 CA129501-01A1, R01 CA100750, R01 CA125541-03, R01 CA125541, R01 CA129501, R01 CA100750-05A1] Funding Source: Medline
- NHLBI NIH HHS [P01 HL058064-130009, P01 HL058064] Funding Source: Medline
Dysregulation of mesenchymal-epithelial transition factor receptor tyrosine kinase pathway leads to cell proliferation, protection from apoptosis, angiogenesis, invasion, and metastasis. It can be dysregulated through overexpression, constitutive activation, gene amplification, ligand-dependent activation or mutation. New drugs targeting various mesenchymal-epithelial transition factor pathways are being investigated with promising results.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据