Article
Nutrition & Dietetics
Anja M. Sedlmeier, Sebastian E. Baumeister, Andrea Weber, Beate Fischer, Barbara Thorand, Till Ittermann, Marcus Doerr, Stephan B. Felix, Henry Voelzke, Annette Peters, Michael F. Leitzmann
Summary: The study indicates that fat mass and fat-free mass show opposing associations with mortality risk. Excess fat mass is related to increased mortality risk, while fat-free mass is protective against mortality risk.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2021)
Article
Endocrinology & Metabolism
Zhijun Ying, Chi Pang Wen, Huakang Tu, Wanlu Li, Sai Pan, Yizhan Li, Yihong Luo, Zecheng Zhu, Min Yang, Zhenya Song, David Ta-Wei Chu, Xifeng Wu
Summary: The study found that both excessively high and low fat mass index (FMI) and fat-free mass index (FFMI) are associated with increased all-cause mortality in the Chinese population. The associations between FMI, FFMI, and the risk of death varied across subgroups and causes of death.
Article
Public, Environmental & Occupational Health
Mie Agermose Gram, Anja Olsen, Zorana Jovanovic Andersen, Anne Tjonneland, Lene Mellemkjaer
Summary: This study examined the association between body fat mass, fat-free mass, and other anthropometric measures and breast cancer in postmenopausal women according to use of hormone replacement therapy (HRT). Among postmenopausal women who never used HRT, a higher body fat mass index (BFMI) was associated with breast cancer in women aged 65 years or older. There was no statistically significant association between any of the body composition measures and breast cancer incidence in ever-users of HRT.
ANNALS OF EPIDEMIOLOGY
(2023)
Article
Immunology
X. J. Lee, A. J. Stewardson, L. J. Worth, N. Graves, T. M. Wozniak
Summary: The study found that Escherichia coli urinary tract infections had the most significant impact on hospital length of stay among the 5 studied pathogens, and that antimicrobial-resistant infections resulted in higher healthcare costs for patients infected with third-generation cephalosporin or methicillin-resistant strains.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Endocrinology & Metabolism
Shelley M. Vanderhout, Charles D. G. Keown-Stoneman, Catherine S. Birken, Deborah L. O'Connor, Kevin E. Thorpe, Jonathon L. Maguire
Summary: This study found that compared to reduced fat (0.1-2%) milk, consumption of whole milk was associated with lower zBMI and lower risk of overweight and obesity.
INTERNATIONAL JOURNAL OF OBESITY
(2021)
Article
Geriatrics & Gerontology
Tiberiu A. Pana, Sheng Hui Kioh, Samuel R. Neal, Maw Pin Tan, Sumaiyah Mat, Alireza Moayyeri, Robert N. Luben, Nicholas J. Wareham, Kay-Tee Khaw, Phyo K. Myint
Summary: This cohort study aimed to determine the association between body fat percentage (BF%), incident fractures and calcaneal broadband ultrasound attenuation (BUA). The results showed that higher BF% is associated with lower risk of fractures in women, while increasing BF% >23% is associated with higher risk of hip fractures in men.
Article
Public, Environmental & Occupational Health
Scott Waterfield, Tom G. Richardson, George Davey Smith, Linda M. O'Keeffe, Joshua A. Bell
Summary: This study found that genetic variants are more strongly associated with adiposity than with lean mass. Sex-specific childhood genetic risk scores have a larger impact on obesity, while the impact of adulthood genetic risk scores is smaller.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Medicine, General & Internal
Seo Hee Ko, Sang Jun Park, Na Young Kim, Woohyuk Jeon, Dong Ah Shin, Shin Hyung Kim
Summary: Preoperative handgrip strength was found to be associated with length of hospital stay and patient outcomes after lumbar fusion surgery, with patients in the low handgrip strength group experiencing longer hospital stay and a higher incidence of postoperative complications.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Multidisciplinary Sciences
Yuan-Liang Zheng, Ri-Sheng Huang, Xiao-Yong Liang
Summary: The study aims to investigate the association between postoperative length of stay (LOS) after lobectomy and operative adverse events, and to identify the best predictors and risk factors associated with prolonged LOS. The risk factors associated with prolonged LOS after lobectomy include age >= 60 years old, being a current smoker, having an ASA classification of 2 or higher, and having stage IIIA disease. Prolonged LOS after lobectomy is significantly associated with various operative adverse events.
Article
Pharmacology & Pharmacy
Masato Takase, Tomohiro Nakamura, Naho Tsuchiya, Mana Kogure, Fumi Itabashi, Akira Narita, Takumi Hirata, Naoki Nakaya, Yohei Hamanaka, Junichi Sugawara, Kichiya Suzuki, Nobuo Fuse, Akira Uruno, Eiichi N. Kodama, Shinichi Kuriyama, Ichiro Tsuji, Shigeo Kure, Atsushi Hozawa
Summary: This study found that a higher body fat percentage is associated with hypertension, even in non-obese individuals. Reducing both FMI and FFMI may play an important role in preventing hypertension. However, the relationship between FFMI and hypertension in the lowest FMI group might be weak for men.
CLINICAL AND EXPERIMENTAL HYPERTENSION
(2021)
Article
Physiology
Agnieszka Chwalczynska, Aureliusz Kosendiak, Krzysztof Andrzej Sobiech, Waldemar Andrzejewski
Summary: The study aimed to personalize the classification of body weight using the fat-fat-free (FFF) index and to develop classification standards for the FFF index for young men. The researchers examined 1,642 adolescents and analyzed their body composition using body composition analyzers. The study found that the FFF index is a better evaluation method compared to BMI and fat mass. New classification standards for the FFF index were proposed based on sexual development and physiological changes. The use of the FFF index in assessing body weight can be beneficial for preventing overweight and obesity.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Medicine, General & Internal
Darren Troeman, Derek Hazard, Leen Timbermont, Surbhi Malhotra-Kumar, Cornelis van Werkhoven, Martin Wolkewitz, Alexey Ruzin, Herman Goossens, Marc Bonten, Stephan Harbarth, Frangiscos Sifakis, Jan Kluytmans, Jelle Vlaeminck, Tuba Vilken, Basil Britto Xavier, Christine Lammens, Marjolein van Esschoten, Fleur Paling, Claudia Recanatini, Frank Coenjaerts, Bret Sellman, Christine Tkaczyk, Susanne Weber, Miquel Bart Ekkelenkamp, Lijckle van der Laan, Bastiaan Vierhout, Elodie Couve-Deacon, Miruna David, David Chadwick, Martin Llewelyn, Andrew Ustianowski, Antony Bateman, Damian Mawer, Biljana Carevic, Sonja Konstantinovic, Zorana Djordjevic, Maria Dolores del Toro-Lopez, Juan Pablo Horcajada Gallego, Dolores Escudero, Miquel Pujol Rojo, Julian Torre-Cisneros, Francesco Castelli, Giuseppe Nardi, Pamela Barbadoro, Mait Altmets, Piret Mitt, Adrian Todor, Serban-Ion Bubenek-Turconi, Dan Corneci, Dorel Sandesc, Valeriu Gheorghita, Radim Brat, Ivo Hanke, Jan Neumann, Tomas Tomas, Wim Laffut, Anne-Marie van den Abeele
Summary: This multicenter cohort study evaluated surgical patients from 33 hospitals in 10 European countries and found that carriage of Staphylococcus aureus was associated with an increased risk of postoperative S aureus infections. Preoperative S aureus colonization, nonremovable implants, undergoing mastectomy or neurosurgery, and body mass index were independently associated with S aureus infections.
Article
Surgery
Akikazu Yago, Yu Ohkura, Masaki Ueno, Kentoku Fujisawa, Yusuke Ogawa, Hayato Shimoyama, Masayuki Urabe, Shusuke Haruta, Harushi Udagawa
Summary: Fat-free mass index (FFMI) is an important prognostic factor for patients undergoing esophagectomy, with no correlation with other nutritional factors.
WORLD JOURNAL OF SURGERY
(2022)
Article
Health Care Sciences & Services
Swapnil Patel, Abbas Alshami, Steven Douedi, Natasha Campbell, Mohammad Hossain, Arman Mushtaq, Dana Tarina, Brett Sealove, David Kountz, Kim Carpenter, Ellen Angelo, Vito Buccellato, Kenneth Sable, Elliot Frank, Arif Asif
Summary: JSUMC implemented a series of interventions, such as root cause analysis and obstacle interventions, which successfully reduced hospital length of stay and saved medical costs.
Article
Cardiac & Cardiovascular Systems
Marguerite Paille, Thomas Senage, Jean-Christian Roussel, Thibaut Manigold, Matthieu Piccoli, Guillaume Chapelet, Thierry Le Tourneau, Matilde Karakachoff, Gilles Berrut, Laure de Decker, Anne Sophie Boureau
Summary: This study examined the association between preoperative CGA and hospital LOS after combined cardiac surgery, finding significant differences in LOS and ICU LOS between the CGA and non-CGA groups. Multivariable analysis revealed significant associations between hospital LOS and CGA, renal function, mitral replacement, and complications. Prospective studies are needed to validate the use of systematic preoperative CGA in improving postoperative outcomes for vulnerable patients undergoing cardiac surgery in an aging population.
ANNALS OF THORACIC SURGERY
(2021)
Article
Clinical Neurology
Haryadi Prasetya, Lucas A. Ramos, Thabiso Epema, Kilian M. Treurniet, Bart J. Emmer, Ido R. van den Wijngaard, Guang Zhang, Manon Kappelhof, Olvert A. Berkhemer, Albert J. Yoo, Yvo B. E. W. M. Roos, Robert J. van Oostenbrugge, Diederik W. J. Dippel, Wim H. van Zwam, Aad van der Lugt, Bas A. J. M. de Mol, Charles B. L. M. Majoie, Ed van Bavel, Henk A. Marquering
Summary: The study introduces a semi-automated quantitative reperfusion measure, qTICI, which provides a similar prognostic value for functional outcome compared to eTICI score. It was found that in adjusted regression analyses, both qTICI and eTICI were independently associated with functional outcome.
INTERNATIONAL JOURNAL OF STROKE
(2021)
Article
Cardiac & Cardiovascular Systems
Hatem Al-Farra, Ameen Abu-Hanna, Bas A. J. M. de Mol, W. J. ter Burg, Saskia Houterman, Jose P. S. Henriques, Anita C. J. Ravelli
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2020)
Review
Cardiac & Cardiovascular Systems
Eric Wierda, Cathelijne Dickhoff, Martin Louis Handoko, Liane Oosterom, Wouter Emmanuel Kok, Y. de Rover, B. A. J. M. de Mol, Loek van Heerebeek, Jutta Maria Schroeder-Tanka
Review
Cardiac & Cardiovascular Systems
E. Wierda, D. van Veghel, A. Hirsch, B. A. J. M. de Mol
NETHERLANDS HEART JOURNAL
(2020)
Article
Primary Health Care
Idar Mappangara, Andriany Qanitha, Cuno S. P. M. Uiterwaal, Jose P. S. Henriques, Bastianus A. J. M. de Mol
BMC FAMILY PRACTICE
(2020)
Article
Cardiac & Cardiovascular Systems
Theodor Fischlein, Bart Meuris, Thierry Folliguet, Kavous Hakim-Meibodi, Martin Misfeld, Thierry Carrel, Marian Zembala, Elisa Cerutti, Federico M. Asch, Axel Haverich
Summary: This study reports the midterm clinical outcomes of a self-expandable sutureless aortic valve. The results show that this technology is associated with low mortality and morbidity rates, and good hemodynamic performance.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2022)
Article
Biology
Ricardo R. Lopes, Hidde Bleijendaal, Lucas A. Ramos, Tom E. Verstraelen, Ahmad S. Amin, Arthur A. M. Wilde, Yigal M. Pinto, Bas A. J. M. de Mol, Henk A. Marquering
Summary: This study utilized transfer learning for ECG-based detection of PLN gene mutation, demonstrating that this method can improve the accuracy and efficiency of rare disease detection models.
COMPUTERS IN BIOLOGY AND MEDICINE
(2021)
Article
Medicine, General & Internal
Ben Swinkels, Jurrien ten Berg, Johannes Kelder, Freddy Vermeulen, Wim Jan van Boven, Bas de Mol
Summary: Impaired left ventricular function, severe prosthesis-patient mismatch, and increased aortic cross-clamp time were found to be independent predictors of decreased long-term survival after aortic valve replacement. Patients with a mechanical prosthesis had a higher risk of major bleeding events, and younger age did not protect patients with a mechanical prosthesis against major bleeding events.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Medicine, General & Internal
Riccardo Cocchieri, Bertus van de Wetering, Marco Stijnen, Robert Riezebos, Bastian de Mol
Summary: The article highlights the importance of reducing procedure-related patient injury and discomfort in minimally invasive cardiac surgery (MICS) through innovation and collaboration across bio-medical engineering sub-specialties. It emphasizes the need for focused interaction between engineers, industry, and surgeons to address unmet patient or professional needs. Additionally, the use of training and simulation models is crucial for safe and effective use of novel techniques in MICS.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Medicine, General & Internal
Sarah W. E. Baalman, Ricardo R. Lopes, Lucas A. Ramos, Jolien Neefs, Antoine H. G. Driessen, WimJan P. van Boven, Bas A. J. M. de Mol, Henk A. Marquering, Joris R. de Groot
Summary: Thoracoscopic surgical ablation for atrial fibrillation has been proven effective, and machine learning techniques were used in this study to investigate how baseline characteristics can predict AF recurrence. Multiple ML models were trained and variable selection significantly improved model performance, especially in predicting AF recurrence in younger patients.
Article
Cardiac & Cardiovascular Systems
Hatem Al-Farra, Anita C. J. Ravelli, Jose P. S. Henriques, Saskia Houterman, Bas A. J. M. de Mol, Ameen Abu-Hanna
Summary: A new mortality prediction model (MPM) for transcatheter aortic valve implantation (TAVI) was developed and validated in this study. The model showed good discrimination and calibration, outperforming the currently available models. It can provide valuable information for preprocedural risk assessment and patient counseling.
CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS
(2022)
Article
Cardiac & Cardiovascular Systems
Marco Mamprin, Ricardo R. Lopes, Jo M. Zelis, Pim A. L. Tonino, Martijn S. van Mourik, Marije M. Vis, Svitlana Zinger, Bas A. J. M. de Mol, Peter H. N. de With
Summary: Machine learning models were used to improve risk stratification for TAVI patients, with a dedicated exchange protocol demonstrating the robustness of the models across different centers. The models developed with larger datasets showed similar or higher prediction accuracy during external validation, suggesting the potential for broader application in different clinical scenarios.
JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE
(2021)
Article
Cardiac & Cardiovascular Systems
Hatem Al-Farra, Bas A. J. M. de Mol, Anita C. J. Ravelli, W. J. P. P. ter Burg, Saskia Houterman, Jose P. S. Henriques, Ameen Abu-Hanna
Summary: This study updated and internally validated the FRANCE-2 and ACC-TAVI models using a recent TAVI cohort from the Netherlands Heart Registration. The updated models showed improved performance, with internal validation results better than external validation studies, and ACC-TAVI outperformed FRANCE-2 in temporal validation.
IJC HEART & VASCULATURE
(2021)
Article
Medicine, Research & Experimental
Noemi Vanerio, Marco Stijnen, Bas A. J. M. de Mol, Linda M. Kock
ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION
(2020)
Article
Cardiac & Cardiovascular Systems
Ben M. Swinkels, Jurrien M. Ten Berg, Johannes C. Kelder, Freddy E. Vermeulen, Wim Jan Van Boven, Bas A. de Mol
Summary: This study found that longer aortic cross-clamp time was independently associated with decreased late survival in patients with severe aortic stenosis after isolated aortic valve replacement. Longer cardiopulmonary bypass time was not found to have a similar association.
INTERACTIVE CARDIOVASCULAR AND THORACIC SURGERY
(2021)