Article
Medicine, General & Internal
Mi Jin Kim, Jae Suk Baek, Jung A. Kim, Seul Gi Cha, Jeong Jin Yu
Summary: Preoperative cerebral and abdominal regional oxygen saturations in neonates with critical congenital heart disease vary according to cardiac diagnosis. Severe atrioventricular valvar regurgitation patients have the lowest ScO2 levels. ScO2 tends to decrease gradually over time, suggesting a higher risk of hypoxic brain injury with longer time to surgery.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Anesthesiology
L. Meng, Y. Sun, X. Zhao, D. M. Meng, Z. Liu, D. C. Adams, D. L. Mcdonagh, M. Rasmussen
Summary: A systematic review was conducted on the effects of phenylephrine on blood pressure, cardiac output, cerebral blood flow, and cerebral tissue oxygen saturation. The results showed that phenylephrine increases blood pressure while decreasing cardiac output. Although it increases cerebral blood flow, it decreases cerebral tissue oxygen saturation. The effects of the drug on cardiac output, cerebral blood flow, and cerebral tissue oxygen saturation are closely related to the magnitude of the changes in blood pressure induced by phenylephrine. There is no significant difference in the effects of phenylephrine between awake and anesthetized humans.
Article
Pediatrics
Petra Lemmers, Daniel Vijlbrief, Manon Benders, Thomas Alderliesten, Moniek Veldhuis, Wim Baerts, Corine Koopman-Esseboom, Floris Groenendaal, Frank van Bel
Summary: This study investigated the relationship between the duration of patency of the ductus arteriosus (PDA), cerebral oxygenation, magnetic resonance imaging-determined brain growth, and neurodevelopmental outcome in preterm infants. The results showed that a prolonged duration of PDA was associated with reduced cerebellar growth and suboptimal neurodevelopmental outcome at the age of 2 years.
JOURNAL OF PEDIATRICS
(2023)
Article
Medicine, General & Internal
Melinda Matyas, Mihaela Iancu, Monica Hasmasanu, Anca Man, Gabriela Zaharie
Summary: This study revealed that IVH, inotrope support, and episodes of apnea can lead to a decreased cerebral oxygen saturation in preterm newborns.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Biotechnology & Applied Microbiology
Yoo Hwan Kim, Seung-Ho Paik, Youngmin Kim, Jaechul Yoon, Yong Suk Cho, Dohern Kym, Jun Hur, Wook Chun, Beop-Min Kim, Byung-Jo Kim
Summary: This study assessed the burn extent and depth in patients with burns using a custom-built 36-channel functional near-infrared spectroscopy system. Hemodynamic tissue signals measured during fNIRS showed significant differences between different burn categories, indicating that functional near-infrared spectroscopy can help with the early judgment of burn extent and depth by reflecting differences in the oxygen saturation levels in the skin.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
George M. Hoffman, Robert A. Niebler, John P. Scott, Rebecca A. Bertrandt, Martin K. Wakeham, Nathan E. Thompson, Nancy S. Ghanayem, Eckehard A. Stuth, Michael E. Mitchell, Ronald K. Woods, Viktor Hraska, Kathleen A. Mussatto, James S. Tweddell
Summary: This study identified interventions associated with low-CO state occupancy and transition through bivariate analysis of hemodynamic states. Maintaining or increasing inodilator and hemoglobin levels were found to improve hemodynamic conditions and predict successful transitions from the low-CO state in the future.
ANNALS OF THORACIC SURGERY
(2021)
Article
Pediatrics
Ena Suppan, Gerhard Pichler, Corinna Binder-Heschl, Bernhard Schwaberger, Berndt Urlesberger
Summary: Near-infrared spectroscopy (NIRS) measurement of regional cerebral tissue oxygen saturation (rcStO2) in neonatology has attracted great interest. Studies have demonstrated its feasibility in the delivery room and neonatal intensive care unit, and reference ranges for different gestational ages, modes of delivery, and devices have been published. However, interpreting the absolute values and trends of rcStO2 remains challenging, which limits its routine use.
FRONTIERS IN PEDIATRICS
(2022)
Article
Multidisciplinary Sciences
Tim Hermans, Katherine Carkeek, Anneleen Dereymaeker, Katrien Jansen, Gunnar Naulaers, Sabine Van Huffel, Maarten De Vos
Summary: In neonates with hypoxic ischemic encephalopathy, the use of wavelet coherence between EEG power and rSO2 is a promising method for assessing neurovascular coupling. However, fluctuations in SpO2 limit the reliability of previous methods. To address this issue, partial wavelet coherence is proposed to eliminate the influence of SpO2. Furthermore, the study investigates the additional value of novel NVC biomarkers compared to traditional EEG and NIRS biomarkers for identifying brain injury.
SCIENTIFIC REPORTS
(2023)
Article
Pediatrics
Jingjing Zhao, Rong Wu, Wei Liu, Manman Li, Wei Wang, Lihua Li
Summary: This study aimed to assess the effects of the change of mechanical ventilator mode on cerebral oxygen saturation (SrO2) level in neonates by using near-infrared spectroscopy (NIRS). The results showed that SrO2 level increased after the change of ventilation mode, with the most prominent increase observed at 10 minutes after the change to noninvasive ventilation.
Article
Anesthesiology
Li Zhang, Lu Liu, Zhiqiu Zhong, Hengfang Jin, Jian Jia, Lingzhong Meng, Xuming Mo, Xiaohua Shi
Summary: Suboptimal tissue perfusion and oxygenation may lead to perioperative complications in neonates and infants undergoing complicated aortic coarctation repair. Monitoring cerebral and somatic tissue oxygen saturation during surgery revealed distinct patterns influenced by selective cerebral perfusion, impacting their correlation with mean arterial pressure and partial pressure of arterial blood carbon dioxide. Further research is needed to determine the outcome impact of combined tissue oxygen saturation monitoring.
BMC ANESTHESIOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Marioli Carrasco-Quiroz, Maria del Alamo-Sanza, Ana Maria Martinez-Gil, Rosario Sanchez-Gomez, Victor Martinez-Martinez, Ignacio Nevares
Summary: This study investigates the effect of different levels of oxygen saturation on the final characteristics of wines made from Tempranillo and Garnacha grape extracts. Controlled oxygen saturation levels were used to simulate possible oxidation before bottling. The results demonstrate the relationship between the oxidation state of wine and changes in its chemical composition, and provide insight into the impact of oxygen consumption before bottling on wines subjected to high and single doses of oxygen.
Article
Multidisciplinary Sciences
Jonas B. Fischer, Lisa Kobayashi Frisk, Felix Scholkmann, Raquel Delgado-Mederos, Mercedes Mayos, Turgut Durduran
Summary: The study found that wearing masks can lead to small but significant changes in cerebral hemodynamics, comparable to those seen during daily life activities. This research provides a basis for larger studies on the effects of mask wearing in different populations and situations.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Pediatrics
Siv Steinsmo Odegard, Hans Torp, Turid Follestad, Martin Leth-Olsen, Ragnhild Stoen, Siri Ann Nyrnes
Summary: This study evaluated the normal cerebral blood flow in healthy neonates using a novel Doppler ultrasound system. The results showed a decrease in arterial low frequency oscillations (LFO) during the first 2 days of life, while venous LFO did not change significantly. These findings may represent normal physiological changes related to the transitional period.
FRONTIERS IN PEDIATRICS
(2022)
Review
Geriatrics & Gerontology
Ke-qiang He, Sheng Wang, Wei Zhang, Qiang Liu, Xiao-qing Chai
Summary: Current evidence shows that patients with postoperative delirium have lower cerebral oxygen saturation (ScO2), and desaturation of ScO2 may increase the incidence of postoperative delirium, indicating the role of ScO2 in underlying pathological mechanisms. However, insignificant differences were detected in baseline/lowest ScO2 value during intraoperative and postoperative periods. Additionally, there were no statistically significant associations for intraoperative and postoperative low ScO2 effect on postoperative delirium risk.
AGING CLINICAL AND EXPERIMENTAL RESEARCH
(2022)
Article
Surgery
Sara J. Kuik, Martin van der Heide, Janneke L. M. Bruggink, Arend F. Bos, A. A. Eduard Verhagen, Elisabeth M. W. Kooi, Jan B. F. Hulscher
Summary: Measuring r(int)SO(2), but not r(c)SO(2), seems to be helpful in estimating the survival rate of preterm infants after surgery for NEC. The levels of r(int)SO(2), C-reactive protein, lactate, and fraction of inspired oxygen differed significantly between survivors and non-survivors. Only r(int)SO(2) remained significant in the multiple regression model.