4.4 Article

Parameter inference for an individual based model of chytridiomycosis in frogs

期刊

JOURNAL OF THEORETICAL BIOLOGY
卷 277, 期 1, 页码 90-98

出版社

ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
DOI: 10.1016/j.jtbi.2011.02.010

关键词

Chytridiomycosis; Individual based model; Agent based model; Parameter inference; Bayesian inference

资金

  1. NSF [EF-0723563]

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Individual based models (IBMs) and Agent based models (ABMs) have become widely used tools to understand complex biological systems. However, general methods of parameter inference for IBMs are not available. In this paper we show that it is possible to address this problem with a traditional likelihood-based approach, using an example of an IBM developed to describe the spread of chytridiomycosis in a population of frogs as a case study. We show that if the IBM satisfies certain criteria we can find the likelihood (or posterior) analytically, and use standard computational techniques, such as MCMC, for parameter inference. (C) 2011 Elsevier Ltd. All rights reserved.

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