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Synthesis and antimicrobial activity of a new series of 1,4-dihydropyridine derivatives

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SERBIAN CHEMICAL SOC
DOI: 10.2298/JSC091127003K

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1,4-dihydropyridine; thiosemicarbazide; condensation; antimicrobial activity

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  1. State Government of Tamil Nadu

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A series of 1,4-dihydropyridine derivatives (1a-g) were prepared from Hantzsch syntheses. The compounds 1a-g were reacted with thiosemicarbazide to give the new series of compounds 2a-g. IR, H-1-NMR, C-13-NMR, mass spectral and elemental analysis confirmed the synthesized compounds. The synthesized compounds were also screened for their antimicrobial activity.

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