Spatial stochastic modelling of the Hes1 gene regulatory network: intrinsic noise can explain heterogeneity in embryonic stem cell differentiation

URDME: a modular framework for stochastic simulation of reaction-transport processes in complex geometries

(2012) Brian Drawert et al.   BMC Systems Biology

Influence of the Nuclear Membrane, Active Transport, and Cell Shape on the Hes1 and p53–Mdm2 Pathways: Insights from Spatio-temporal Modelling

(2012) Marc Sturrock et al.   BULLETIN OF MATHEMATICAL BIOLOGY

Dancing on DNA: Kinetic Aspects of Search Processes on DNA

(2011) Anahita Tafvizi et al.   CHEMPHYSCHEM

A Spatio-Temporal Model of Notch Signalling in the Zebrafish Segmentation Clock: Conditions for Synchronised Oscillatory Dynamics

(2011) Alan J. Terry et al.   PLoS One

Hes1 Oscillations Contribute to Heterogeneous Differentiation Responses in Embryonic Stem Cells

(2011) Taeko Kobayashi et al.   Genes

Hes1 regulates embryonic stem cell differentiation by suppressing Notch signaling

(2010) Taeko Kobayashi et al.   GENES TO CELLS

Spatio-temporal modelling of the Hes1 and p53-Mdm2 intracellular signalling pathways

(2010) Marc Sturrock et al.   JOURNAL OF THEORETICAL BIOLOGY

A model of yeast cell-cycle regulation based on multisite phosphorylation

(2010) Debashis Barik et al.   Molecular Systems Biology

Spatio-temporal correlations can drastically change the response of a MAPK pathway

(2010) K. Takahashi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The cyclic gene Hes1 contributes to diverse differentiation responses of embryonic stem cells

(2009) T. Kobayashi et al.   GENES & DEVELOPMENT

Rapid and sustained nuclear–cytoplasmic ERK oscillations induced by epidermal growth factor

(2009) Harish Shankaran et al.   Molecular Systems Biology

Stochastic modelling for quantitative description of heterogeneous biological systems

(2009) Darren J. Wilkinson   NATURE REVIEWS GENETICS

Exploring the roles of noise in the eukaryotic cell cycle

(2009) S. Kar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Simulation of Stochastic Reaction-Diffusion Processes on Unstructured Meshes

(2009) Stefan Engblom et al.   SIAM JOURNAL ON SCIENTIFIC COMPUTING

Computational Models of the Notch Network Elucidate Mechanisms of Context-dependent Signaling

(2009) Smita Agrawal et al.   PLoS Computational Biology

Stochastic Simulation of Enzyme-Catalyzed Reactions with Disparate Timescales

(2008) Debashis Barik et al.   BIOPHYSICAL JOURNAL

The stochastic nature of biochemical networks

(2008) Vahid Shahrezaei et al.   CURRENT OPINION IN BIOTECHNOLOGY

Dissecting the dynamics of the Hes1 genetic oscillator

(2008) Hiroshi Momiji et al.   JOURNAL OF THEORETICAL BIOLOGY

Oscillations in Notch Signaling Regulate Maintenance of Neural Progenitors

(2008) Hiromi Shimojo et al.   NEURON

Control of the Reversibility of Cellular Quiescence by the Transcriptional Repressor HES1

(2008) L. Sang et al.   SCIENCE