期刊
JOURNAL OF THE ROYAL SOCIETY INTERFACE
卷 6, 期 -, 页码 S671-S678出版社
ROYAL SOC
DOI: 10.1098/rsif.2009.0190.focus
关键词
bacteria; lipopolysaccharide; reflectivity; Monte Carlo simulation
资金
- German Science Foundation [Ta 259/6]
- State Baden-Wurttemberg
- DAAD
- Advanced Foods and Materials Network of Centres of Excellence (AFMNet-NCE)
- Atlantic Innovation Fund
Lipopolysaccharide (LPS) monolayers deposited on planar, hydrophobic substrates were used as a defined model of outer membranes of Pseudomonas aeruginosa strain dps 89. To investigate the influence of ions on the (out-of-plane) monolayer structure, we measured specular X-ray reflectivity at high energy (22 keV) to ensure transmission through water. Electron density profiles were reconstructed from the reflectivity curves, and they indicate that the presence of Ca(2+) ions induces a significant change in the conformation of the charged polysaccharide head groups (O-side chains). Monte Carlo simulations based on a minimal computer model of LPS molecules allow for the modelling of 100 or more molecules over 10(-3) s and theoretically explained the tendency found by experiments.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据