期刊
JOURNAL OF THE NEUROLOGICAL SCIENCES
卷 310, 期 1-2, 页码 202-207出版社
ELSEVIER
DOI: 10.1016/j.jns.2011.06.006
关键词
Parkinson's disease; Brain imaging; Dopamine; Subthalamic nucleus; Impulsivity; Impulse control disorders
资金
- Canadian Institutes of Health Research [64423] Funding Source: Medline
- CIHR [MOP 64423] Funding Source: Medline
In the last few years it has become clear that impulsivity is a complex behaviour composed of different domains and dependent on different neural networks. The proposed pathogenetic mechanisms for the emergence of impulsivity disorders in Parkinson's Disease (PD) can be broadly separated into three potentially interacting processes: the contribution of premorbid susceptibility to impulsivity, the contribution of the disease itself to the behaviour and the potential contribution of therapeutic agents. Growing evidence suggests that dopamine and the subthalamic nucleus are playing a certain role in the pathophysiology of different aspects of impulsivity. In this review, we summarise the main concepts defining various components of impulsivity both in healthy subjects and patients affected by PD. (C) 2011 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据