Article
Oncology
Qian Wang, Meng Ru, Yaning Zhang, Tamara Kurbanova, Paolo Boffetta
Summary: The study suggests that higher dietary intake of phytoestrogens may reduce the risk of lung cancer in a Caucasian-dominant population, particularly among smokers, non-small cell histology, males, and females, with no significant linear trend observed. Further research is needed to confirm these findings and investigate the mechanisms of action and interactions with smoking and endogenous estrogens.
Article
Oncology
Santino S. Butler, Brandon A. Mahal, Javid J. Moslehi, Anju Nohria, Edward C. Dee, Rishi Makkar, Amanda Whitbeck, Janet Wangoe, Kent W. Mouw, Paul L. Nguyen, Vinayak Muralidhar
Summary: This study found that the use of ADT plus RT, compared with RT alone, does not increase the risk of cardiovascular mortality in men with radiation-managed prostate cancer, even among those with preexisting comorbidities and cardiovascular disease.
Article
Oncology
Susan R. Sturgeon, David A. Sela, Eva P. Browne, Jonah Einson, Asha Rani, Mohamed Halabi, Thomas Kania, Andrew Keezer, Raji Balasubramanian, Regina G. Ziegler, Catherine Schairer, Karl T. Kelsey, Kathleen F. Arcaro
Summary: Analysis of WBC DNA methylation in breast cancer cases and noncases revealed potential associations with breast cancer risk, although the specific patterns were not conclusively identified. Further research is needed to better understand the link between prediagnostic WBC DNA methylation marks and breast cancer.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2021)
Article
Nutrition & Dietetics
Jennifer M. Mongiovi, Jo L. Freudenheim, Kirsten B. Moysich, Susan E. McCann
Summary: This study found an association between higher glycemic index and glycemic load with a lower risk of ovarian cancer, but caution should be taken in interpreting the results as they may have been influenced by limitations such as lack of variability in dietary intake. Additional studies are needed to better understand the driving factors behind these associations.
JOURNAL OF NUTRITION
(2021)
Article
Nutrition & Dietetics
Jungeun Lim, Hyokyoung G. G. Hong, Stephanie J. Weinstein, Mary C. Playdon, Amanda J. Cross, Rachael Stolzenberg-Solomon, Neal D. Freedman, Jiaqi Huang, Demetrius Albanes
Summary: The effects of vitamin E supplementation on cancer and other chronic diseases are unclear. This study compared the serum metabolomic profile of different vitamin E dosages and found significant associations between vitamin E supplementation and various metabolites, including C-22 lactone sulfate and androgens. The study also discovered distinct responses in steroid hormone pathways based on vitamin E dosages. Further research is needed to better understand the biological effects of vitamin E in relation to cancer and other chronic diseases.
Article
Oncology
Lauren M. Hurwitz, Nadine Dogbe, Kathryn Hughes Barry, Stella Koutros, Sonja Berndt
Summary: This study found that obesity indirectly increases the risk of prostate cancer mortality by affecting the efficacy of prostate cancer screening. Higher BMI was negatively associated with prostate cancer incidence but positively associated with prostate cancer mortality. However, this association was not influenced by screening outcomes.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
(2023)
Article
Oncology
Guo-Chao Zhong, Qian Zhu, Dong Cai, Jie-Jun Hu, Xin Dai, Jian-Ping Gong, Wei-Ping Sun
Summary: This study found that high consumption of ultra-processed foods is associated with an increased risk of pancreatic cancer, with a stronger correlation observed in individuals under the age of 65. These findings suggest that reducing the intake of ultra-processed foods may be beneficial in decreasing the incidence of pancreatic cancer.
INTERNATIONAL JOURNAL OF CANCER
(2023)
Article
Endocrinology & Metabolism
Margaret Hoyt, Yiqing Song, Sujuan Gao, Jacquelynn O'Palka, Jianjun Zhang
Summary: Overweight in young adulthood and obesity in middle adulthood may contribute to an elevated risk of pancreatic cancer. However, there is no association between prediagnostic adulthood BMI trajectory and pancreatic cancer risk.
Article
Biochemistry & Molecular Biology
Kathleen M. McClain, Joshua N. Sampson, Jessica L. Petrick, Kaitlyn M. Mazzilli, Robert E. Gerszten, Clary B. Clish, Mark P. Purdue, Loren Lipworth, Steven C. Moore
Summary: This study found that six serum metabolites were associated with the risk of kidney cancer, and three of these metabolites had independent associations in the mutually adjusted model. These metabolites may point to new biological pathways relevant to kidney malignancy.
Article
Nutrition & Dietetics
Zongze Jiang, Huilin Chen, Ming Li, Wei Wang, Chuanwen Fan, Feiwu Long
Summary: In this study, moderate consumption of carrots was found to be associated with a lower incidence of colorectal cancer, while the association with dietary carrot and beta-carotene intake was not significant. Smoking status was found to modify the association between dietary carrot intake and colorectal cancer incidence.
FRONTIERS IN NUTRITION
(2022)
Article
Medicine, General & Internal
Holli A. Loomans-Kropp, Paul Pinsky, Asad Umar
Summary: The study found that aspirin use was not associated with a reduced risk of developing breast, bladder, esophageal, gastric, pancreatic, or uterine cancers in older individuals. However, it was linked to improved survival in bladder and breast cancer patients.
Article
Nutrition & Dietetics
Robert Thomas, Basma Greef, Alex McConnachie, Bethany Stanley, Madeleine Williams
Summary: The study found a small positive association between drinking tea and a reduced risk of prostate cancer among tea drinkers, but this does not support starting to drink tea for men who did not previously drink tea to reduce the risk. Further research is needed to determine whether tea is justified for future prospective nutritional intervention studies investigating prostate cancer prevention.
BRITISH JOURNAL OF NUTRITION
(2022)
Article
Urology & Nephrology
Kendrick Yim, Chaoran Ma, Sigrid Carlsson, Hans Lilja, Lorelei Mucci, Kathryn Penney, Adam S. Kibel, Scott Eggener, Mark A. Preston
Summary: Adding percent free PSA to total PSA improved prediction of clinically significant prostate cancer and fatal prostate cancer. Free PSA can be used to stratify risk in screening and reduce unnecessary prostate biopsies.
JOURNAL OF UROLOGY
(2023)
Article
Oncology
Kenechukwu Chudy-Onwugaje, Wen-Yi Huang, L. Joseph Su, Mark P. Purdue, Christine C. Johnson, Lingxiao Wang, Hormuzd A. Katki, Kathryn Hughes Barry, Sonja I. Berndt
Summary: In this study, a beneficial role for both aspirin and ibuprofen in preventing advanced adenoma and curbing progression to recurrence and cancer among older adults was observed during long-term follow-up.
Article
Multidisciplinary Sciences
James P. Long, Yu Shen
Summary: Breast cancer research has shown the prognostic significance of cancer detection method, and this study investigates this phenomenon in the lung component of the PLCO screening trial. The results suggest that lung cancer detection method has independent prognostic value exceeding that of commonly used variables in lung cancer prognostic models.
SCIENTIFIC REPORTS
(2023)
Article
Hematology
Mark P. Purdue, Qing Lan, Otoniel Martinez-Maza, Martin M. Oken, William Hocking, Wen-Yi Huang, Dalsu Baris, Betty Conde, Nathaniel Rothman
Article
Oncology
Mark P. Purdue, Qing Lan, Rachel Bagni, William G. Hocking, Dalsu Baris, Douglas J. Reding, Nathaniel Rothman
Article
Medicine, General & Internal
Martin M. Oken, Willam G. Hocking, Paul A. Kvale, Gerald L. Andriole, Saundra S. Buys, Timothy R. Church, E. David Crawford, Mona N. Fouad, Claudine Isaacs, Douglas J. Reding, Joel L. Weissfeld, Lance A. Yokochi, Barbara O'Brien, Lawrence R. Ragard, Joshua M. Rathmell, Thomas L. Riley, Patrick Wright, Neil Caparaso, Ping Hu, Grant Izmirlian, Paul F. Pinsky, Philip C. Prorok, Barnett S. Kramer, Anthony B. Miller, John K. Gohagan, Christine D. Berg
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2011)
Article
Oncology
C. Martin Tammemagi, Paul F. Pinsky, Neil E. Caporaso, Paul A. Kvale, William G. Hocking, Timothy R. Church, Thomas L. Riley, John Commins, Martin M. Oken, Christine D. Berg, Philip C. Prorok
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
(2011)
Article
Oncology
William G. Hocking, Martin C. Tammemagi, John Commins, Martin M. Oken, Paul A. Kvale, Ping Hu, Lawrence R. Ragard, Tom L. Riley, Paul Pinsky, Thomas M. Beck, Philip C. Prorok
Article
Medicine, General & Internal
Martin C. Tammemaegi, Hormuzd A. Katki, William G. Hocking, Timothy R. Church, Neil Caporaso, Paul A. Kvale, Anil K. Chaturvedi, Gerard A. Silvestri, Tom L. Riley, John Commins, Christine D. Berg
NEW ENGLAND JOURNAL OF MEDICINE
(2013)
Article
Radiology, Nuclear Medicine & Medical Imaging
Constantine A. Gatsonis
Article
Medicine, General & Internal
Sreelatha Chalasani, Mark Hennick, William Hocking, Gene Shaw, Benjamin Lawler
CLINICAL MEDICINE & RESEARCH
(2013)
Article
Oncology
C. Martin Tammemagi, Matthew T. Freedman, Timothy R. Church, Martin M. Oken, William G. Hocking, Paul A. Kvale, Ping Hu, Thomas L. Riley, Lawrence R. Ragard, Philip C. Prorok, Christine D. Berg
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2007)
Article
Cardiac & Cardiovascular Systems
HS Vats, WG Hocking, SH Rezkalla
NATURE CLINICAL PRACTICE CARDIOVASCULAR MEDICINE
(2006)
Article
Oncology
MM Oken, PM Marcus, P Hu, TM Beck, W Hocking, PA Kvale, J Cordes, TL Riley, SD Winslow, S Peace, DL Levin, PC Prorok, JK Gohagan
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
(2005)
Article
Oncology
JK Gohagan, PM Marcus, RM Fagerstrom, PF Pinsky, BS Kramer, PC Prorok, S Ascher, W Bailey, B Brewer, T Church, D Engelhard, M Ford, M Fouad, M Freedman, E Gelmann, D Gierada, W Hocking, S Inampudi, B Irons, CC Johnson, A Jones, G Kucera, P Kvale, K Lappe, W Manor, A Moore, H Nath, S Neff, M Oken, M Plunkett, H Price, D Reding, T Riley, M Schwartz, D Spizarny, R Yoffie, C Zylak