Article
Chemistry, Physical
Pan Gao, Wei Pu, Pengchong Wei, Miqiu Kong
Summary: Research investigates the adhesion at nanoscale of PDMS-silica interface by establishing a molecular model. The results show that PDMS with 30 repeat units has the highest adhesion energy, but temperature has the greatest proportional change in adhesion energy. Increasing temperature within a certain range benefits adhesion energy improvement, along with the molecular weight or polarity of PDMS terminal group.
APPLIED SURFACE SCIENCE
(2022)
Article
Chemistry, Multidisciplinary
Liu Yang, Haijun Wang
Summary: As known, head loss has a significant impact on water transmission, especially under vibration conditions. This study investigated the mechanism of how vibrations affect head loss by measuring wettability and conducting Materials Studio simulations. Different pipeline materials showed varied effects on water drops, and the roughness of the pipelines influenced their wettability, leading to head loss. The molecular dynamic simulation results confirmed that the interaction energy between water drops and pipelines' surfaces was the main cause of head loss, which was affected by vibrations.
APPLIED SCIENCES-BASEL
(2022)
Review
Engineering, Multidisciplinary
Maciej Kozlik, Jan Harpula, Piotr J. Chuchra, Magdalena Nowak, Wojciech Wojakowski, Pawel Gasior
Summary: Drug-eluting stents (DES) have shown superior efficacy compared to bare metal stents and balloon angioplasty, and are now widely used in percutaneous revascularization procedures. The constant development of DES includes improvements in the stent platform design, materials used, coating techniques, and antiproliferative agents. Understanding the impact of different aspects of stents on clinical outcomes is crucial, given the vast number of available DES platforms. This review discusses the current status of coronary stents and the influence of stent material, strut design, and coating techniques on cardiovascular outcomes.
Article
Chemistry, Physical
In-Chul Yeh, Garrett M. Tow
Summary: Force field parameter sets for ammonium perchlorate were evaluated and compared with quantum mechanical calculations of surface energies. The parameter set with the best agreement was selected and used to study the interactions between AP surfaces and a polymer binder. The simulated interfacial energies agreed qualitatively with experimental observations, supporting the role of hydroxyl groups in the surface dependence of the AP-HTPB interfacial tension.
JOURNAL OF PHYSICAL CHEMISTRY C
(2023)
Article
Thermodynamics
Pujith Rajaguru Senapathy Vijayaratnam, John Arthur Reizes, Tracie Jacqueline Barber
Summary: The study aims to investigate the significance of drug transport from malapposed stent struts and whether a streamlined strut profile can mitigate adverse haemodynamics while enhancing drug uptake.
INTERNATIONAL JOURNAL OF NUMERICAL METHODS FOR HEAT & FLUID FLOW
(2022)
Review
Health Care Sciences & Services
Flavius-Alexandru Gherasie, Chioncel Valentin, Stefan-Sebastian Busnatu
Summary: In patients undergoing percutaneous coronary intervention, second-generation drug-eluting stents (DES) are the gold standard for revascularization. These stents reduce the need for repeat revascularizations compared to conventional stents. However, there are concerns about the risk of stent thrombosis and recoil in certain lesion types. Ultra-thin strut stents offer advantages such as improved deliverability and reduced thrombosis risk, but they may not be suitable for all lesions.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Engineering, Environmental
Pan Xu, Zhijie Shang, Guoxuan Li, Zhengrun Chen, Wanxiang Zhang
Summary: In this work, the simultaneous decarburization, desulfurization, and dehydration of biogas using ionic liquids (ILs) was proposed. Screening of 400 ILs composed of 20 cations and 20 anions was done based on the COSMO-RS model. The study found that 1,3-dimethylimidazolium methylsulfate [C1MIM][MeSO4] showed promising potential as an absorbent for the process. The research provided theoretical insights for the development of new ILs for biogas purification.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2023)
Article
Biochemistry & Molecular Biology
Mukesh Kumar, Robert J. Gaivin, Shenaz Khan, Yuriy Fedorov, Drew J. Adams, Weiyang Zhao, Hsueh-Yun Lee, Xinghong Dai, Chris G. Dealwis, Jeffrey R. Schelling
Summary: Diabetes is a major public health problem with end organ complications. This study aimed to identify potential inhibitors of FATP2 as a treatment for diabetes. By constructing a homology model and conducting virtual screening, 23 hits were selected from a diverse compound library. Two compounds showed high affinity inhibition of FATP2 and were further characterized. This study demonstrates the feasibility of using homology modeling and in silico screening to identify potential inhibitors of FATP2 for diabetes treatment.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Review
Engineering, Biomedical
Lili Tan, Xiangxiu Wang, Kungshan Yuan, Tieying Yin, Ruolin Du, Li Shen, Zhirong Zhu, Suhua Yu, Haijun Zhang, Guixue Wang
Summary: This review systematically analyzes the history, research hotspots, and emerging trends of drug-eluting stents (DES) in the last two decades from the perspective of structural and temporal dynamics. The results show that DES is still a hot field with extensive scientific collaborations, and there are active topics and emerging research subfields in different periods.
BIOACTIVE MATERIALS
(2023)
Article
Materials Science, Composites
Rui Chen, Jialin Zhang, Hongbo Chen, Gao Li, Jiqiang Hu, Hanqi Zhang, Bing Wang
Summary: Based on the demand in the aerospace field, we are researching the brittleness problem of phthalonitrile resin (PN75), a high-temperature resistant material. Combining molecular dynamics simulations with experiments has become a meaningful way to reduce research and development time and cost. Revealing microscale mechanisms through atomic simulations and providing guidance for experiments is one of the current scientific hotspots.
COMPOSITES SCIENCE AND TECHNOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Rafal Wolny, Ilona Kowalik, Rafal Januszek, Jacek Bil, Tomasz Figatowski, Marek Milewski, Brunon Tomasiewicz, Tomasz Walczak, Bruno Hrymniak, Piotr Desperak, Piotr Niezgoda, Magdalena Chudzik, Lukasz Kuzma, Pawel Kralisz, Fabrizio D'Ascenzo, Damian Hudziak, Milosz Jaguszewski, Krzysztof Reczuch, Jacek Kubica, Robert J. Gil, Slawomir Dobrzycki, Stanislaw Bartus, Mariusz Gasior, Andrzej Ochala, Adam Witkowski, Wojciech Wojakowski, Wojciech Wanha
Summary: Implantation of a thin-DES in patients with R-ISR is associated with a lower risk of repeated revascularization compared with angioplasty with a DEB. The risks of device-oriented adverse cardiac events and all-cause mortality were similar after thin-DES or DEB in both unadjusted and propensity score-matched cohorts.
KARDIOLOGIA POLSKA
(2022)
Article
Multidisciplinary Sciences
Amir Shamloo, Mohammad Ali Bakhtiari, Mahdi Tohidloo, Saeed Seifi
Summary: In this study, the motion regime of fullerene molecules on substrates with different shapes and temperatures was investigated using classical molecular dynamics method. It was found that different fullerene molecules exhibited different motion behaviors under specific conditions, with C-20, C-76, and C-80 molecules being the most suitable candidates in most cases. The concave geometry substrate demonstrated better performance in straight-line movement. However, C-72 molecule showed less favorable performance in terms of range of movement and diffusion coefficients.
SCIENTIFIC REPORTS
(2022)
Article
Engineering, Mechanical
Hongyun Cai, Caixia Zhang, Fuping Li, Mengmeng Liu, Tao Zhang, Hongyan Chu, Zhifeng Liu
Summary: Hydrophilic polymer coatings on artificial implants exhibit excellent tribological properties. The friction properties of polymer coatings are influenced by salt ion factors. By using atomic force microscopy (AFM) and molecular dynamics (MD) simulation, it was found that adjusting the cation radius in lubricants can change the adhesion between friction pairs and ultimately affect the magnitude of friction.
Article
Medicine, General & Internal
Na Xu, Lin Jiang, Yi Yao, Jingjing Xu, Ru Liu, Huanhuan Wang, Ying Song, Lijian Gao, Zhan Gao, Xueyan Zhao, Bo Xu, Yaling Han, Jinqing Yuan
Summary: This study compares the clinical outcomes of using biodegradable polymer drug-eluting stents (BP-DES) and durable polymer drug-eluting stents (DP-DES) in complex percutaneous coronary intervention (CPCI). The results show that both CPCI and non-CPCI patients have a risk of adverse events in the mid- to long-term, and the effects of BP-DES and DP-DES differ in CPCI patients.
CHINESE MEDICAL JOURNAL
(2023)
Article
Engineering, Chemical
Pan Xu, Zhijie Shang, Guoxuan Li, Wanxiang Zhang, Zhengrun Chen
Summary: In this study, the simultaneous decarburization, desulfurization, and dehydration of biogas were achieved using a quaternary ammonium salt-based deep eutectic solvent (DES). Screening of 100 DESs composed of different hydrogen bond acceptors and donors showed that TEAC, TEAB, TEG, and BDO-based DESs were the most promising absorbents. These DESs exhibited excellent selective absorption performance for CO2. Molecular surface electrostatic potential (ESP) analysis and independent gradient model based on Hirshfeld partition (IGMH) analysis revealed the separation mechanism of DESs. The results provide theoretical insights for the development of new DESs for biomethane purification.
SEPARATION AND PURIFICATION TECHNOLOGY
(2023)
Article
Construction & Building Technology
Jessica A. Rosewitz, Habibeh Ashouri Choshali, Nima Rahbar
CEMENT & CONCRETE COMPOSITES
(2019)
Article
Engineering, Biomedical
Sina Askarinejad, Joshua E. Johnson, Nima Rahbar, Karen L. Troy
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2019)
Article
Biophysics
Zachary E. Goldblatt, Habibeh Ashouri Choshali, Heather A. Cirka, Vivian Liang, Qi Wen, Dannel McCollum, Nima Rahbar, Kristen L. Billiar
BIOPHYSICAL JOURNAL
(2020)
Article
Construction & Building Technology
Shuai Wang, Rajib B. Mallick, Nima Rahbar
CONSTRUCTION AND BUILDING MATERIALS
(2020)
Article
Engineering, Biomedical
Emmanuel O. Onche, Salifu T. Azeko, John D. Obayemi, Oluwaseun K. Oyewole, Nneka B. Ekwe, Nima Rahbar, Winston O. Soboyejo
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2020)
Article
Engineering, Multidisciplinary
Sina Askarinejad, Faezeh Shalchy, Nima Rahbar
Summary: Nacre's exceptional mechanical properties are attributed to its multilayered structure, nanoscale features, and the role of interfaces. Understanding the interphase properties is crucial for enhancing material toughness.
COMPOSITES PART B-ENGINEERING
(2021)
Article
Nanoscience & Nanotechnology
T. Bond, A. Badmos, R. A. Ahmed, J. D. Obayemi, A. Salifu, N. Rahbar, W. O. Soboyejo
Summary: This paper presents a study on the indentation size effects in structural metals/alloys at the micron scale, including 6061 aluminum alloy, titanium, and Ti-6Al-4V. The size dependence of indentation hardness is explained using strain gradient plasticity theories. The study compares the resulting material length scales with microstructures and previously reported values, and discusses the implications of the results for plasticity and hardness modeling at the micron scale.
MATERIALS SCIENCE AND ENGINEERING A-STRUCTURAL MATERIALS PROPERTIES MICROSTRUCTURE AND PROCESSING
(2022)
Article
Biophysics
Habibeh Ashouri Choshali, Kristen L. Billiar, Nima Rahbar
Summary: In this study, the stress fields within cells were investigated using computational and experimental methods, revealing the presence of anisotropy. It was found that substantial stress concentration occurs in the central region, contradicting the assumption of uniform anisotropy. A more realistic non-uniform anisotropy model was introduced based on experimental observations, effectively eliminating stress concentration. The study provides a physics-based mechanism to explain the low alignment of stress fibers in cells and potentially explains certain biological phenomena.
BIOMECHANICS AND MODELING IN MECHANOBIOLOGY
(2022)
Article
Engineering, Biomedical
Alycia Abbott, Mattea E. Gravina, Mobin Vandadi, Nima Rahbar, Jeannine M. Coburn
Summary: This study explored the impact of modifying lyophilization primary drying parameters on the properties of protein-based porous scaffolds. It was found that changing the drying duration and temperature can result in scaffolds with tunable properties. Additionally, the use of different concentrations of the protein solution led to different effects on in vitro cell culturing.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
(2023)
Article
Materials Science, Biomaterials
Mobin Vandadi, Kenan P. Fears, Manoj K. Kolel-Veetil, Nima Rahbar
Summary: Biomaterials serve as an important inspiration for the development of strong and tough materials. A novel class of nanomaterials, synthesized through side-chain to-side-chain polymerization of cyclic beta-peptide rings, exhibits outstanding mechanical properties. Molecular dynamics simulations reveal that polymerized peptides can withstand stress and have high strain-to-failure values, compared to brittle behavior of unpolymerized peptides. Additionally, the strength of cyclic peptides is higher in water than in a vacuum.
ACS BIOMATERIALS SCIENCE & ENGINEERING
(2023)
Article
Materials Science, Biomaterials
Mobin Vandadi, Kenan P. Fears, Manoj K. Kolel-Veetil, Nima Rahbar
Summary: Biomaterials serve as an important inspiration for the development of strong and tough materials, leading to the recent development of improved synthetic materials. Through the side-chain-to-side-chain polymerization of cyclic beta-peptide rings, a new class of nanomaterials with exceptional mechanical properties has been introduced. Molecular dynamics simulations are used to explore the mechanics of this polymerization process and demonstrate the differences in strength between polymerized and unpolymerized cyclic peptides. The simulations are conducted in both aqueous and vacuum environments to investigate the influence of water on the mechanical properties. The results reveal that unpolymerized peptides behave as brittle materials, while polymerized ones exhibit a significant strain-to-failure after initial failure. Moreover, the strength of cyclic peptides is higher in water compared to a vacuum.
ACS BIOMATERIALS SCIENCE & ENGINEERING
(2023)
Article
Chemistry, Multidisciplinary
Shuai Wang, Suzanne Scarlata, Nima Rahbar
Summary: The article describes a method that allows for the rapid curing of enzymatic construction materials under ambient conditions using low-power lasers and the incorporation of nanoparticles, supporting on-site manufacturing capability for construction materials.
CELL REPORTS PHYSICAL SCIENCE
(2022)
Article
Materials Science, Multidisciplinary
Shuai Wang, Suzanne F. Scarlata, Nima Rahbar
Summary: This paper introduces a novel method to create a negative-emission enzymatic construction material (ECM) with self-healing capabilities, by catalyzing the condensation of CO2 and water to form calcium carbonate crystals. The resulting ECM has high strength and modulus, providing a new direction for developing environmentally friendly and low-cost construction materials.
Editorial Material
Materials Science, Multidisciplinary
Nima Rahbar
Article
Materials Science, Multidisciplinary
Daniel R. Williams, Daniel J. Nurco, Nima Rahbar, Kristie J. Koski
Article
Engineering, Biomedical
Xinyao Zhu, Yifan Liu, Jing Ye, Wei Xu, Xuexia Zhao, Tianyan Liu
Summary: This study reveals the adverse effect of acid on dentin in terms of degradation of its fracture toughness. The peritubular dentin plays a significant role in enhancing the dentin's fracture resistance capability. The findings highlight the importance of structural integrity for dentin.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2024)
Article
Engineering, Biomedical
Priya Ranganathan, Vijayakumari Sugumaran, Bargavi Purushothaman, Ajay Rakkesh Rajendran, Balakumar Subramanian
Summary: The study aims to design and fabricate an ultra-easier multi-functional biomedical polymeric scaffold loaded with unique equimolar Ca:P phasic bioactive glass material. The results showed that the G:BG (1:2) ratio is the more appropriate composition for enhanced bio-mineralization and higher surface area. The scaffold can induce mitogenesis in osteoblast cells for hard tissue regeneration and rapid collagen secretion in fibroblast cells for soft tissue regeneration.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2024)
Article
Engineering, Biomedical
Ziad Guerfi, Oum keltoum Kribaa, Hanane Djouama
Summary: Hydroxyapatite, a biocompatible and bioactive ceramic material, has been widely studied in fields such as orthopedics and plastic surgery. The use of computational tools, especially density functional theory, has become increasingly important in research. In this study, Hydroxyapatite was synthesized using the double decomposition method and quantum mechanical computations were performed using density functional theory. The experimental and computational results confirmed the successful synthesis of Hydroxyapatite and showed good agreement in spectroscopic characterizations.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2024)
Article
Engineering, Biomedical
Sally AbdulHussain Kadhum, Nassier A. Nassir
Summary: In this research, porous composites were successfully prepared and reinforced for bone scaffold applications. The functional groups, pore structure, and composition distribution of the materials were characterized using techniques such as FTIR, Atomic Force Microscopy (AFM), and Scanning Electron Microscopy (SEM).
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2024)
Article
Engineering, Biomedical
Veronika Geiger, Felicitas Mayinger, Moritz Hoffmann, Marcel Reymus, Bogna Stawarczyk
Summary: The study investigated the mechanical properties of four additively manufactured denture base resins in different measurement environments, and found that the measurement environment impacts the strength and fracture toughness of the materials.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2024)
Article
Engineering, Biomedical
Junxiao Wang, Amatjan Sawut, Rena Simayi, Huijun Song, Xueying Jiao
Summary: The development of cost-effective and eco-friendly conductive hydrogels with excellent mechanical properties, self-healing capabilities, and non-toxicity is of great significance in the field of biosensors.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2024)
Article
Engineering, Biomedical
Yijun Zhou, Lisa Ho, Ayan Samanta, Philip Procter, Cecilia Persson
Summary: In this study, soft, non-setting biomaterials based on Hyalectin gels and different morphological parameters of hydroxyapatite (HA) particles were evaluated as potential augmentation materials for orthopaedic implant fixation. The results showed that constructs reinforced with irregularly shaped nano-HA particles and spherically shaped micro-HA particles had significantly higher pull-out force compared to the control group.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2024)
Article
Engineering, Biomedical
Mehdi Jahandardoost, Donald Ricci, Abbas S. Milani, Mohsen Jahandardoost, Dana Grecov
Summary: Tubular flow diverters are important for treating cerebral aneurysms. A new design called VR-eCLIPs has been developed to cover the neck of challenging bifurcation aneurysms. A finite element model has been used to simulate the implantation processes of VR-eCLIPs and assess potential plastic deformation.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2024)
Article
Engineering, Biomedical
Marek Traczynski, Adam Patalas, Katarzyna Roslan, Marcin Suszynski, Rafa l Talar
Summary: This article evaluates the forces acting on intravenous needles during insertion into the skin and selects the most suitable model for future research. The experimental results show that needle size, insertion angle, and insertion speed have an influence on the measured force values.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2024)
Article
Engineering, Biomedical
Chester Jar, Andrew Archibald, Monica Gibson, Lindsey Westover
Summary: This study evaluates the ASIST technique for assessing the stability of dental implants. The results show that the ASIST technique can reliably measure the interfacial stiffness of dental implants, which is not significantly influenced by different abutment types. This method may provide an improved non-invasive way to measure the stability of dental implants.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2024)
Article
Engineering, Biomedical
Ali Kamali, Kaveh Laksari
Summary: In this paper, a UNet-based neural network model (El-UNet) is developed to infer the spatial distributions of mechanical parameters. The El-UNet shows superior performance in terms of accuracy and computational cost compared to other neural network models. A self-adaptive spatial loss weighting approach is proposed, which achieves the most accurate reconstructions in equal computation times.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2024)
Article
Engineering, Biomedical
Chunyan Yu, Yanju Lu, Jinhui Pang, Lu Li
Summary: In this study, a safe and effective hemostatic composite sponge was developed by combining chitosan and hydroxypropylmethylcellulose (HPMC). The sponge exhibited excellent flexibility and rapid hemostatic ability in vitro. In vivo assessments showed that the sponge had the shortest clotting time and minimal blood loss.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2024)
Article
Engineering, Biomedical
Zhongliang Yu, Lin Yu, Junjie Liu
Summary: The study proposes incorporating functionally graded tablets into nacreous composites to enhance both stiffness and damping properties. Analytical formulae and numerical experiments demonstrate the effectiveness of this design, surpassing existing homogeneous composites in performance.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2024)
Article
Engineering, Biomedical
Marc Graham, Sandra Klinge
Summary: This study investigates the macroscopic diffusion behavior of heterogeneous gels using a homogenization method in a finite element framework. Two materials, calcifying PDMA and PAAm, were studied, and the results show that the diffusivity of PDMA has a strong nonlinear dependence on the solute molecule radius.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2024)
Article
Engineering, Biomedical
Abdur-Rasheed Alao
Summary: This study aimed to find the optimal sandblasting parameters for roughening YTZP surfaces. Through experimental and statistical analysis, the best setting was found to be IA = 45 degrees, AP = 110 μm, ST = 20 s, and P = 400 kPa, which resulted in the maximum surface roughness, phase transformation, and shear bond strength.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2024)
